Grace Smith said:It’s the same old story... this is really a question for a hematologist, which is such an incredibly narrow subspecialty that it is practically impossible to provide a real answer unless you actually are one. I will attempt to weigh in based on what I can gather from my textbooks.
From what I can gather—assuming I haven't completely misread the tests—it seems they ran this specifically to determine which type of Non-Hodgkin lymphoma we are looking at, given the suspicion of chronic lymphocytic leukemia (CLL). Personally, I find those CD8 levels (cytotoxic lymphocytes) to be far too high, as are the NK cells...
In cases of chronic lymphocytic leukemia (CLL), you look for B-lymphocytes expressing markers like CD19, CD20, and CD23 (though CD22 can show up too), alongside the simultaneous expression of the CD5 marker; normally, CD5 is found on T-lymphocytes, but in CLL, it manifests on the B-lymphocytes...
Since your results show those specific markers on the B-lymphocytes (CD19, 20, and 22), I suspect that, based on those findings alone, one could actually substantiate a diagnosis of CLL.
The only thing giving me pause is the T-lymphocyte finding... and again, I must emphasize how difficult this is to answer without knowing the clinical suspicion that prompted the test in the first place. Those details are absolutely vital for interpreting any result, and since I am neither a hematologist nor an internist, but merely an enthusiastic student, I am essentially just feeling my way through the dark and offering mere hunches.
Please, feel free to jump in if anyone has further information or wishes to correct me, as I certainly had to consult several texts before putting this together.
I missed this response until now, and by then, I hadn't even had the chance to see how the original poster was doing, but I would kindly ask that people exercise much more caution when addressing such highly specific questions; please refrain from making any serious diagnoses based solely on laboratory reports.