I went ahead and read through the first post and typed out all those values... but honestly, I’m sitting here wondering if I’m actually going to get an answer at all?!
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Drew Nguyen47 said:Hey everyone,
I was wondering if anyone here knows a bit more about blood work than I do, because I'm a total novice and could use a little help 😁 making sense of my recent results. Basically, my creatinine came back a bit low—it’s at 59, when the typical range is usually between 63 and 107 umol/L—and my ALP is also slightly down at 41, instead of the usual 54 to 119 U/L. I'm 30 years old 😍. From what I've been digging up online, both of these markers might suggest my body is feeling a little run down, maybe due to some vitamin deficiencies or something similar in my diet. Does anyone have any idea what might cause these numbers to dip like this, or maybe some advice on how I can get them back where they should be? 🤷 Thanks in advance! 🙏
Regarding that low creatinine level, it might be a good idea to go ahead with a urinalysis and maybe an ultrasound of your kidneys just to be safe... though honestly, those numbers aren't actually that far off from the normal range.
As for the ALP, or alkaline phosphatase, that value is actually made up of several different parts—things coming from your bones, your liver, and even your intestines. When you see that single "total" number on a lab report, it's really just the sum of all those pieces.
So, you'd really need to look closer at your lab report to see which specific type of alkaline phosphatase is showing the decrease! If there happens to be an issue with your kidneys... it's entirely possible that the drop is being driven by the bone-related component.
Take care!
LATEST LAB RESULTS FROM MAY 2012
PARATHYROID HORMONE 24 ...ref range 15-65
CALCIUM 2.46... ref range 2.14-2.53
PHOSPHATE 0.99...ref range 0.79-1.42
24-HOUR URINARY CALCIUM 7.3...ref range 2.5-6.2
URINARY PHOSPHATE 19.4...ref range 12.9-42
24-HOUR URINE VOLUME 2200...ref range 600-1600
BONE-SPECIFIC ALKALINE PHOSPHATASE 50...ref range 11.6-29.6
VITAMIN D 50...ref range above 75
OSTEOASCALCIN 26.9...ref range 11-43
BETA-CROSSLAPS 0.251...ref range up to 0.57
PARATHYROID HORMONE (FROM 2010) WAS HIGH—10.2...ref range 1.10-7.30
INORGANIC PHOSPHATE (SEPTEMBER 2011) WAS HIGH—1.47...ref range 0.79-1.42
DEXA SCAN NORMAL
MEDICAL HISTORY:
Dealing with bone-related issues for about 3 years now.
It all started with this strange sensitivity and a burning sensation right along my ribs. Then, my costal cartilage—you know, where the ribs meet the sternum—started thickening up. There are days when the stinging in that spot is so intense I can barely stand the feeling of clothes touching my skin. On top of that, I sometimes get this nagging discomfort and a burning sensation in my hand joints.
My bone-specific alkaline phosphatase seems to be on a steady climb over the last three years (ref range up to 29.6)... it was at 32, then bumped to 38, and now it’s sitting at 50!
I still don't have an official diagnosis. One doctor suggested it might just be a Vitamin D deficiency (which was measured at 50 back in May).
Honestly, it feels a bit hard to wrap my head around the idea that a minor Vitamin D shortage could be responsible for three years of constant symptoms and this creeping rise in my alkaline phosphatase levels. Does that really sound right to you guys?
Is this upward trend in alkaline phosphatase something I should be worried about?
PLEASE LET ME KNOW WHAT YOU THINK... WHAT SHOULD MY NEXT STEPS BE?
THANK YOU ALL SO MUCH IN ADVANCE!
PARATHYROID HORMONE 24 ...ref range 15-65
CALCIUM 2.46... ref range 2.14-2.53
PHOSPHATE 0.99...ref range 0.79-1.42
24-HOUR URINARY CALCIUM 7.3...ref range 2.5-6.2
URINARY PHOSPHATE 19.4...ref range 12.9-42
24-HOUR URINE VOLUME 2200...ref range 600-1600
BONE-SPECIFIC ALKALINE PHOSPHATASE 50...ref range 11.6-29.6
VITAMIN D 50...ref range above 75
OSTEOASCALCIN 26.9...ref range 11-43
BETA-CROSSLAPS 0.251...ref range up to 0.57
PARATHYROID HORMONE (FROM 2010) WAS HIGH—10.2...ref range 1.10-7.30
INORGANIC PHOSPHATE (SEPTEMBER 2011) WAS HIGH—1.47...ref range 0.79-1.42
DEXA SCAN NORMAL
MEDICAL HISTORY:
Dealing with bone-related issues for about 3 years now.
It all started with this strange sensitivity and a burning sensation right along my ribs. Then, my costal cartilage—you know, where the ribs meet the sternum—started thickening up. There are days when the stinging in that spot is so intense I can barely stand the feeling of clothes touching my skin. On top of that, I sometimes get this nagging discomfort and a burning sensation in my hand joints.
My bone-specific alkaline phosphatase seems to be on a steady climb over the last three years (ref range up to 29.6)... it was at 32, then bumped to 38, and now it’s sitting at 50!
I still don't have an official diagnosis. One doctor suggested it might just be a Vitamin D deficiency (which was measured at 50 back in May).
Honestly, it feels a bit hard to wrap my head around the idea that a minor Vitamin D shortage could be responsible for three years of constant symptoms and this creeping rise in my alkaline phosphatase levels. Does that really sound right to you guys?
Is this upward trend in alkaline phosphatase something I should be worried about?
PLEASE LET ME KNOW WHAT YOU THINK... WHAT SHOULD MY NEXT STEPS BE?
THANK YOU ALL SO MUCH IN ADVANCE!
I’m 27 years old and I've been dealing with some pretty frustrating bone issues for the last 2 or 3 years now.
It all started with this weird sensitivity and a burning sensation right in my ribs—that was actually the very first sign. Since then, things have progressed to a thickening around my sternum and this intense, burning feeling where my ribs meet the breastbone.
Every once in a while, I also get that same burning sensation deep in my arm bones.
I’ve ended up running several different rounds of tests because I wanted to be absolutely sure about everything, so I’ll just list the specific values that haven't been looking quite right lately:
PARATHYROID HORMONE IS NORMAL (it was only slightly elevated one single time)
ALKALINE PHOSPHATASE IN BONES IS RISING... over a few months, it jumped from 32 up to 50 (ref range is 11.6-29.6)
VITAMIN D IS LOW (ref range is above 75... mine was at 50 when tested 5 months ago)
URINARY CALCIUM IS HIGH (ref range is 2.5-6.2... mine came back at 7.3)
BLOOD CALCIUM IS WITHIN NORMAL LIMITS (though it was elevated just once)
BLOOD PHOSPHORUS (sometimes slightly high, sometimes normal)
OSTEOCALCIN IS WITHIN NORMAL LIMITS
BETA CROSSLAPS ARE WITHIN NORMAL LIMITS
24-HOUR URINE VOLUME IS HIGH (ref range is 600-1600, mine was 2200)
THYROID HORMONES ARE NORMAL
BONE DENSITY SCAN (DEXA) IS WITHIN NORMAL LIMITS
TOTAL PROTEINS ARE WITHIN NORMAL LIMITS
Looking at my symptoms and these lab results... do you think it’s possible that the high alkaline phosphatase in my bones and that burning pain in my rib and sternum area could be caused by my Vitamin D deficiency (which was sitting at 50 back in month 5)?
Also, is there anything else you think I should be getting checked out?
It all started with this weird sensitivity and a burning sensation right in my ribs—that was actually the very first sign. Since then, things have progressed to a thickening around my sternum and this intense, burning feeling where my ribs meet the breastbone.
Every once in a while, I also get that same burning sensation deep in my arm bones.
I’ve ended up running several different rounds of tests because I wanted to be absolutely sure about everything, so I’ll just list the specific values that haven't been looking quite right lately:
PARATHYROID HORMONE IS NORMAL (it was only slightly elevated one single time)
ALKALINE PHOSPHATASE IN BONES IS RISING... over a few months, it jumped from 32 up to 50 (ref range is 11.6-29.6)
VITAMIN D IS LOW (ref range is above 75... mine was at 50 when tested 5 months ago)
URINARY CALCIUM IS HIGH (ref range is 2.5-6.2... mine came back at 7.3)
BLOOD CALCIUM IS WITHIN NORMAL LIMITS (though it was elevated just once)
BLOOD PHOSPHORUS (sometimes slightly high, sometimes normal)
OSTEOCALCIN IS WITHIN NORMAL LIMITS
BETA CROSSLAPS ARE WITHIN NORMAL LIMITS
24-HOUR URINE VOLUME IS HIGH (ref range is 600-1600, mine was 2200)
THYROID HORMONES ARE NORMAL
BONE DENSITY SCAN (DEXA) IS WITHIN NORMAL LIMITS
TOTAL PROTEINS ARE WITHIN NORMAL LIMITS
Looking at my symptoms and these lab results... do you think it’s possible that the high alkaline phosphatase in my bones and that burning pain in my rib and sternum area could be caused by my Vitamin D deficiency (which was sitting at 50 back in month 5)?
Also, is there anything else you think I should be getting checked out?