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High Androstenedione Levels

Started by Jamie Price5 · · 👁 5 views · 7 replies

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Participants Jamie Price5Frank Hughes56Jamie Johnson6Karen Nelson71Scott Patel53Jason Nelson64
Jamie Price5 Jamie Price5 NewcomerOP
2 messages
joined Apr 2008
#1 ·
My androstenedione is through the roof at 90 ng/mol, and my 17-OH progesterone is sitting at 280 ng/mol. My 17-ketosteroids are also way up.
I don’t have any symptoms, except for the fact that my period has completely stopped.
LH and free testosterone are slightly elevated too.
Does anyone have a clue what this could be? I can't get an appointment with an endocrinologist for a while, so I'd really appreciate some insight.
Thanks!!
Frank Hughes56 Frank Hughes56 Member
42 messages
joined Aug 2009
#2 ·
Could it be PCOS?
Jamie Johnson6 Jamie Johnson6 Member
37 messages
joined Mar 2003
#3 ·
What day of your cycle are we looking at? I’m fairly certain you were testing your progesterone and everything else on the same day, right? It was actually quite similar for me—I was sitting at a 17... but after going through some treatments, things finally leveled out and returned to normal.
Time to run to the endocrinologist.
Jamie Price5 Jamie Price5 NewcomerOP
2 messages
joined Apr 2008
#4 ·
They aren't polycystic... I just had my ultrasound done.
As for the tests, I did everything on day 21. I was actually supposed to go on day 3, but I didn't get my referral in time. Plus, my periods are rarely even consistent, so I just went when I could.
Yeah... I'm going to see an endocrinologist as soon as possible.
What kind of meds were you on?
Jamie Johnson6 Jamie Johnson6 Member
37 messages
joined Mar 2003
#5 ·
Jamie Price5 said:It isn't necessarily PCOS... I just had my ultrasound done...
And I actually did all those tests on day 21; they were supposed to be done on day 3, but I didn't get my referral in time, and since my periods are so irregular, I just went whenever I could.
Yeah... I'm definitely going to see an endocrinologist as soon as possible.
What kind of treatment were you on?

In my experience, you really ought to have everything tested between days 3 and 5, except for progesterone. Even though some labs list values based on the cycle, I ended up repeating everything because I made that exact mistake once myself. I completely understand the struggle of trying to schedule testing when your cycle is unpredictable; you try to time everything perfectly, but then the timing shifts, the results end up being off... Honestly, I might even suggest doing that ultrasound again. I remember one OBGYN couldn't see anything at all during my scan, yet two others told me I was a textbook case.

I honestly haven't a clue what else could cause those specific results, other than PCOS—though I don't believe I ever had those "ketosteroid" tests checked.

My own treatment plan was for PCOS, and I only took unknown for my blood sugar levels—I didn't even need the birth control pills, and everything eventually leveled out. You'll find out more from your doctor, as I'm sure they'll want to run additional panels. Just a bit of advice: try to secure your referrals early so you can go exactly on the day they recommend (my endocrinologist prefers day 5, while my OBGYN wants me there by day 3). I tend to be quite proactive about it; I usually prepare everything ahead of time or even pull a few extra tests myself when I arrive at the clinic, otherwise, I feel like nothing ever gets scheduled properly.
Karen Nelson71 Karen Nelson71 Newcomer
4 messages
joined Sep 2009
#6 ·
I probably missed the boat on this thread...
but maybe my experience can help someone out here.
I had the exact same lab results. They sent me on a wild goose chase through endless tests...

It turned out I actually have CAH (congenital adrenal hyperplasia).
I've been on corticosteroids for over a year now, which is the standard treatment for this condition, and everything has stabilized perfectly. My cycle is regular again—it used to be incredibly irregular, happening only once every six months.

The bottom line is... if anyone else is dealing with extremely elevated 17-OHP levels, I strongly suggest you go see Dr. unknown in New York City immediately.
Scott Patel53 Scott Patel53 Member
32 messages
joined Apr 2007
#7 ·
Where in New York City can I get 17 OHP done? thanks
Jason Nelson64 Jason Nelson64 Newcomer
6 messages
joined Nov 2009
#8 ·
Hannah Ward86 said:Where in NYC can I get my 17-OHP tested? Thanks.

Look, I need to have mine drawn next week. I usually go to the Mayo Clinic for all my hormone panels, so I can ask around for you...

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