Need advice: Muscle twitching and spasms

Hey there! What's up?
Hope it’s not a huge deal that I’m starting this thread! If it is, please feel free to move it to the right spot—I honestly scoured the whole forum and just couldn't find a specific topic for this issue.

I've been dealing with this one issue for about 20 days now, and it's really starting to bug me!
Alright, let me give you the quick rundown of what's going on.

My calves were killing me in both legs, so we had to take a total break from working out!
So, I decided to go all out for a week—I tried taking a double dose of magnesium along with my full daily serving of Vitamin B12!

So, the first issue didn't actually clear up, and now I’ve got a whole new situation on my hands. My quads are starting to twitch—just these little, painless spasms in both legs. On top of that, the pain in my calves hasn't budged at all; it's still there in both legs.

I’ve been experimenting with this combo for about ten days now. I started out with magnesium and 100% B12, then decided to throw in Vitamin B1, B6, and Calcium at a full 100% dose. It’s been a solid run!

So, I’ve been dealing with this for about 20 to 25 days now, and honestly, it’s still going strong. On top of the constant pain in my calves, I’m getting these muscle twitches in my quads every 5 to 10 minutes. But get this—now it’s spreading to my arms too! I'm talking triceps and biceps on both sides. It's definitely leveling up.

I’ve been slamming B1, B6, B12, Vitamin C, Vitamin D, Magnesium, and Calcium at like 100 to 200% of my daily value for 20 days straight now!

Nothing’s worked so far. I finally managed to get an appointment with an orthopedist, but I'm stuck waiting a whole month!

Should I go for an EMG, an EEG, or what? I could always just head to a private clinic to get things sorted out quickly. Does anyone have any solid recommendations for a good specialist?

Thanks a million!

EMG, brain magnets, and get your B12, Vitamin D, and ANA checked.

Sean Ward4 said:Get an EMG, a brain MRI, and check your B12, Vitamin D, and Ann levels.

Thanks a million,

I actually had a brain MRI about a year ago because of some dizziness, and I'm not totally sure if I need to redo it now given what's happening, especially since my results were fine back then. But I'll definitely get the rest of those tests done!

Taylor Doyle76 said:Thanks a lot,

I had an MRI because of dizziness about a year ago. I'm not sure if I should redo it now given this situation, though the results were fine back then. I'll get the rest done.

As for supplements, just stick to a basic multivitamin. It’s unlikely you have a deficiency; it's much more likely you're dealing with anxiety.
Was the MRI completely clear? If so—you don't need another one!

Sean Ward4 said:Stick to a basic multivitamin if you’re going to take anything. It’s super unlikely you have a major deficiency, but there’s a huge chance this is just anxiety.
Was your MRI totally clear? If it was—then you’re good!

It was totally clear. Had a brain MRI about 11 months ago.

I honestly don't think I'm deficient since I've always eaten tons of fruits and veggies, plus my supplements.

Can anxiety really cause cramping in all those different spots?

Today, like, my back is vibrating, my elbow is acting up, even my ear feels like it's pulsing, and I get these weird tingling sensations near the veins in my legs—kind of a dull ache after a spasm—in my calf and near the Achilles.

I just can't wrap my head around how anxiety could trigger all of that at once.

P.S. I'm heading in tomorrow to get an Ann test.

If you're dealing with muscle twitching and that tingling, pins-and-needles sensation, it’s likely just Benign Fasciculation Syndrome—provided your MRI and EMG results come back clean. There's a tiny chance it could be related to a tick bite, but I guess the odds are maybe 1 in 100.

Severe anxiety, or Psychosomatics, can cause all sorts of crazy symptoms, but I suppose nobody is ever 100% certain about that either.

Ann is looking into those inflammatory autoimmune diseases, which aren't necessarily bad right away, and the rheumatoid factor too. You should get the RF tested. It's not much...

You really need to get an EMG done immediately to rule out the worst-case scenario. If the EMG comes back clear, then you can start taking things slow...
Those inflamed leaves are a major red flag.
Go see Dr. Miller at Mayo Clinic for the EMG.
Sean Ward4 gave some solid advice there.

Look, you should probably just put all of that behind you.
I am also part of the Boy Scouts of America.
Please stop harping on about all those minerals and vitamins.
When you're getting lab work done, you want the results to be crystal clear—not skewed by whatever you happened to be drinking or doing the night before.

I see you've suggested getting an MRI and an EMG done.
So, we're looking at RF and Ann.
Did they happen to run an EEG as well?

I’m not entirely sure why someone would suggest running a rheumatoid factor test in this specific case—everyone has their own logic, I suppose. While an RF test is most commonly positive in patients with rheumatoid arthritis rather than other autoimmune disorders, there's really no harm in doing it. It's just one more piece of the puzzle.
If you're already planning to spend some money on labs, there are actually much more useful tests to run than just RF. It’s like choosing the right tools for a job; starting with things like potassium, CK, LDH, and CRP would give you a far more complete picture.

I honestly don't quite get the frantic rush over this. Just go ahead and schedule that MRI or EMG and get it done—no need to stress!

I honestly don't get why everyone treats magnesium like it's some kind of magic cure-all for muscle cramps.
I experienced those exact same symptoms when my potassium levels were running low.
That doesn't necessarily mean you're dealing with a deficiency in magnesium, potassium, or anything else.
It seems like everyone here lacks a bit of foresight.

Go join the Boy Scouts of America.
Why is that?
The Boy Scouts of America sent me for blood work, but if they don't include potassium in the panel, I might just have to pay the extra $4 at the lab myself.

Stop obsessing over everything you're consuming.
It looks like you’re taking pretty high doses of just about everything. If you check the label, it actually mentions that excessive vitamin intake can cause temporary neuropathy—which sounds exactly like those symptoms you're describing that fade once you stop. It feels a bit like you're treating Neurobion like candy, taking it without a prescription or any medical guidance.
Unless you’re buying these things just because everyone else is raving about them, there isn't much point. It’s easy to assume someone is having a great time just because they're partaking, but that doesn't mean it's working for you. For instance, some people take steroids and deal with side effects like moon face or irregular cycles, but if it keeps their primary condition under control, they consider it a fair trade-off. In those cases, managing the disease takes priority over the side effects. However, if you're taking something without a medical necessity, you should probably just stop. Don't let the advertisements do your thinking for you; use your own judgment and look out for your own well-being.

Look, if you’re already footing the bill for all those MRIs, EMGs, EEGs, rheumatoid factor tests, and antinuclear antibody screenings—seriously, though?—then you might as well go ahead and cover the CK, LDH, and SSEP tests too.
You could also include the anti-ds-DNA and the DNA profile, along with cryoglobulins.
It’s probably best to go ahead with the lumbar puncture and the CSF analysis too. Better safe than sorry.
Oh, right—I also need to have a muscle biopsy and a skin biopsy done, just to rule out anything like lupus.

We've pretty much covered all the bases now.

Yes, I have a bit of a sarcastic streak.

Go join the Boy Scouts of America.
Could you please describe the symptoms you're experiencing? It helps to think of it like giving a mechanic a clear report on how a car is running—the more specific the details, the easier it is to figure out what's going on.
Cut out all those heavy doses of everything else, unless you were just taking some magnesium because you thought you were running low.

If your doctor doesn't order it, just pay out of pocket for a blood test to check your potassium levels. If those numbers look good, then go ahead and schedule that appointment with the neurologist.

Even after that, you should follow up with any additional tests your doctor recommends. If they don't provide a specific roadmap, just reach out and share your report; then we can all jump in and offer our personal insights on the best next steps to take.

Anything else is just a waste of effort, love, and time.

Brenda Alvarez24 said:Look, you should probably just forget everything that was written there.
I’m actually part of the Boy Scouts of America too!
Dude, seriously, quit obsessing over all those vitamins and minerals!
Look, when you're getting some lab work done, you want those results to be crystal clear. You don't want them messed up because you were out partying or drinking something that masks what's actually going on. You want the real deal, not some skewed data just because you did something stupid beforehand!

I see you're suggesting I go get an MRI and an EMG!
So, we're looking at RF and Ann.
Did they run an EEG too?

I honestly don't get why someone would bother ordering a rheumatoid factor test—it's a bit of a mystery to me, but hey, to each their own! If you're suspecting rheumatoid arthritis, then yeah, an RF test is usually positive in those cases, whereas it shows up way less often in other autoimmune issues. But look, I'll say it again: there's absolutely nothing wrong with running an RF test. It's not like it's going to hurt anyone!
Look, if you’re already burning through cash on labs, there are way better things to prioritize than just RF. You gotta get those potassium, CK, LDH, and CRP levels checked first to get a real baseline!

I honestly don't get the hype behind all this madness. Just go get your MRI, an EMG, and whatever else they're asking for already! Seriously, stop stalling and just hurry up!

I honestly don't get why everyone treats magnesium like it's some kind of holy grail for fixing muscle cramps.
I totally went through those exact same symptoms when my potassium levels were running low!
It doesn't necessarily mean you're running low on magnesium, potassium, or anything else like that!
Nobody around here has any foresight!

Just go join the Boy Scouts of America!
Why though?
So, the Boy Scouts of America sent me in for some blood work... if they don't include the potassium levels, I might just lose it and demand my money back right there in the lab!

Seriously, stop whining about everything you’re eating!
You’re out here popping massive doses of everything under the sun! It’s literally written right there in the instructions that mega-dosing certain vitamins can trigger temporary neuropathy—which sounds exactly like those symptoms you're describing that eventually clear up once you stop. It feels like you’re just treating Neurobion like candy, taking it totally uncontrolled without even a doctor's note or a prescription!
Look, if you're just buying stuff on your own because everyone else is doing it and they seem fine, then hey, maybe you think you’ll feel great too... but that's a trap. I mean, yeah, some people take steroids and end up dealing with things like moon face or messed up cycles, but as long as their underlying condition is under control, they're happy. In those cases, a side effect feels like a small price to pay to actually manage the disease. But that's when there's a medical reason! If you're just taking things for no reason at all? Just stop. Seriously. And quit falling for every single advertisement you see. You've got a brain—use it! Start thinking for yourself as an individual instead of just following the crowd.

Look, if you’re already dropping cash on all those MRIs, EMGs, EEGs, rheumatoid factor tests, and anti-nuclear antibody panels (seriously, though??!), then you might as well go all in and pay for the CK, LDH, and SSEP too!
You can totally go for the anti-ds-DNA and the DNA profile too. Oh, and don't forget about cryoglobulins!
They should definitely be looking into a lumbar puncture and a CSF analysis too. Better safe than sorry!
Oh, and they're doing a muscle biopsy too. Plus a skin biopsy—just to make sure we aren't looking at something like lupus.

Alright, we've pretty much covered just about everything!

Yeah, I'm definitely sarcastic.

Go join the Boy Scouts of America.
So, give me the lowdown! What exactly are you feeling? Lay out all those symptoms for me.
Cut out all that extra nonsense from the equation! Unless you were actually popping magnesium because you felt like you were running low, just drop the rest of it.

Look, if your doctor won't even bother sending over a referral, just bite the bullet and pay out of pocket for a blood test to check your potassium levels. If that comes back totally fine, then go ahead and book that appointment with the neurologist!

And once that's all wrapped up, you'll move on to whatever other tests the doctor puts on your plate. If they don't give you any specific direction, just hit us up and drop your report here! We'll all jump in and share our own personal experiences so we can shower you with advice on exactly what you should do next.

Anything else is just a total waste of your energy, your heart, and your precious time!

Hey there! What's up?

Sorry I missed the message earlier! I was out on the road and couldn't get to my phone. I finally got some bloodwork done, and while my potassium levels were off the charts, my magnesium, B12, and Vitamin D came back within range. The thing is, even though I’ve been slamming 300% of my RDA for B12, it's still just sitting right in the middle of the pack. And don't even get me started on Vitamin D—it's incredibly low. This is despite the fact that I spent half the summer soaking up the sun at the beach without a shirt on and was even taking two different types of supplements! Even my magnesium is just mediocre, which is wild considering I’ve been hitting 400% of my RDA with supplements at times. Just weird, honestly!

So, after all that, I've got my Carotid Doppler and EMG scheduled—just waiting on the actual appointments now! Also, my doctor put me on some heavy-duty Vitamin D drops, 14,000 IU, so I'm taking those every single day.

Just saw this message, so I’m heading back out to get my potassium levels checked again.

P.S. I've been on Lipitor for years now, and someone mentioned it can cause all sorts of issues after taking it long-term.