Dealing with constant fatigue, tremors, and general weakness... any ideas?

Maybe someone else has dealt with this—I’d really value your perspective

I can't even put a name to what I'm going through—the doctors are just as clueless as I am

It all kicked off three weeks ago. Every single day, I was hit with this crushing exhaustion. Then, last Saturday around 5:30 AM, I was seized by these violent tremors—shaking fits that lasted nearly two hours—followed by this unbearable restlessness, like I was trying to crawl out of my own skin. After that comes the weakness... total physical collapse. I couldn't talk, couldn't walk, couldn't even hold a glass. It stayed that way for two weeks. My family was terrified—I couldn't even make it to the doctor on my own; they practically had to carry me. That Saturday, when I could finally stand, I went to the local ER. The doctor there looked completely baffled—claimed she'd never seen anything like this happen to someone my age—and I'm only 25. She gave me some Xanax to calm down, but it did absolutely nothing

As things spiraled, I tried a different hospital, but the doctor there wouldn't even examine me properly—just kept asking pointless questions I didn't have the strength to answer. The worst part? When I asked for blood work, she told me they don't do blood tests on weekends and claimed it wouldn't show anything anyway, then just sent me home. Since then, it's been hell for two weeks straight, and I still have no answers. My primary care physician finally ordered some tests, but given how long the wait times are here in the States... I've already been to the ER twice, only to be given sedatives and an IV, only to come home and find everything right back where it started. It’s been over two weeks before I could even get out of bed, and now these tremors hit every night around 2:30 AM for about an hour—and they happen at the exact same time during the day too
When I try to explain this to medical staff, they just stare at me blankly—and I'm at a complete loss
To top it off, my blood work is perfect—couldn't be better—and my thyroid levels are totally normal
Sorry for the long vent—but if anyone has experienced something similar or has any thoughts
Thanks

Michelle Williams44 said:Maybe someone else has dealt with something similar, or maybe not, but I’d really love to get your take on this.

I don't even know how to put a name to what I'm going through—even the doctors are completely stumped.

It all really kicked off about three weeks ago. Every single day, I was just completely wiped out—this crushing, bone-deep exhaustion. Then, last Saturday morning around 5:30 AM, it hit me like a freight train: these massive, violent tremors that lasted anywhere from an hour to two full hours. Once the shaking stopped, this unbearable restlessness took over, like my skin was too tight and I just wanted to jump right out of it. After that initial chaos, everything collapsed into total weakness. I’m talking "can't even hold a glass of water" weak. I couldn't walk, I couldn't talk—nothing. For two weeks straight, it was like that. My family was absolutely frantic; I couldn't even make it to the doctor's office on my own because they practically had to carry me there. That Saturday, when I finally had enough strength to stand on my own two feet, I made it to the ER at the local clinic. The doctor there looked completely baffled. She told me straight up that in her entire career, she had never seen anything like this happen to someone so young—I'm only 25. She prescribed me some Xanax to try and calm things down, but honestly? It didn't do a damn thing for me.

Things just kept spiraling downward. I ended up at this new hospital, and honestly, the doctor there was useless. She wouldn't even bother giving me a proper exam; she just kept firing off these nonsensical questions that I couldn't even answer. But the absolute kicker? I actually asked her to run a blood test, and she had the nerve to tell me they don't draw blood on the weekends anyway, claiming it wouldn't show anything useful regardless. Then she basically just kicked me out and sent me home. That was the start of a two-week descent into hell. I still have no idea what is actually wrong with me. When I finally saw my primary care physician, she ordered some tests, but knowing how much you have to wait for specialists and labs in this country, it’s going to take forever. To make matters worse, I’ve already been to the ER twice. Both times, all they did was pump me full of sedatives and an IV drip, only for me to get back home and feel exactly the same. It’s been over two weeks before I could even pull myself out of bed, and now I’m dealing with these tremors. They hit me around 2:00 or 3:00 in the morning and last for about an hour, and then they come back at the exact same time every single day.
Every time I sit down in a doctor's office and lay out exactly what I'm going through, they just stare at me with this blank, pale expression like I’ve started speaking a foreign language. It’s incredibly frustrating. I walk out of there feeling more lost than when I walked in, left wondering how the hell I'm supposed to navigate this on my own.
So what if my blood work came back perfect? It’s flawless, I guess. My thyroid levels are right where they should be, too. What’s the catch?
Sorry if this turned into a bit of a novel, but I’d love to hear if anyone else has dealt with something similar or what your take is on all this.
Thanks.

If this happens to you again, get yourself straight to the neurology ER. It’s entirely possible you're looking at some kind of neurological disorder here.

So, let me get this straight—how many doctors have you actually seen up to this point? Four?
And yet, you don't have a single scrap of medical documentation or a lab report to show for it?

Have you had unprotected sex recently, or perhaps come into contact with someone else's blood in some way?
If so, please go get tested for HIV and hepatitis.
That being said, I really don't want to scare you; honestly, I suspect your symptoms don't quite align with those specific illnesses.
If that isn't the case, you might be dealing with something psychological or nerve-related. Stress can wreak havoc on both your physical and mental health in ways you wouldn't believe—I've certainly been there myself.
Take a moment to reflect on what’s been happening in your life lately and what might be weighing on your subconscious. Around age 25, people often hit a breaking point because it's such a difficult time to navigate all the stress, expectations, and heavy responsibilities we're expected to shoulder. It makes you wish you could just pack up, move out to the Rocky Mountains, and herd sheep instead of dealing with all this pressure.

If your primary care physician isn't taking the initiative, you should definitely go ahead and request that referral to a psychiatrist yourself!
It really could be anything at this point—neurological issues, endocrine imbalances, and so on—but I have found that most people presenting with these specific symptoms, or similar conditions, are actually dealing with anxiety. I’ve also noticed that when people visit the ER, the staff almost always asks about stress levels and such, and the reality is that these physical manifestations don't necessarily have to be triggered by a specific, immediate situation.

So, how are things looking now? I went through something remarkably similar last year—or at least, I thought it was tied to the antibiotics I was taking, which was a first for me. My doctor had me on two capsules at a time, and I vividly remember waking up in the middle of the night feeling... well, forgive my choice of words, but it felt like being a junkie going through withdrawal on day one. Just this overwhelming sense of weakness and total helplessness; I could barely pull myself out of bed. When I finally made it to my parents, they told me I looked deathly pale, and then I was hit by this uncontrollable shaking spell. We were completely lost—the panic and restlessness were so intense that we ended up calling 911. The nurse on the line basically brushed me off, suggesting I was just coming down with something and to check my temperature... but how could she not see? I didn't have a fever; I was shaking from pure physical depletion. Since things didn't escalate further, I decided not to head to the ER and instead grabbed some Gatorade with extra sugar. Within fifteen minutes, I started feeling better. After that, I lowered my dosage and went straight to get blood work done. It turned out I have an iron deficiency—something I've been dealing with for a decade now—and nothing else. I started taking multivitamins, and that helped significantly. Thankfully, it hasn't happened like that again; I still deal with bouts of fatigue, but none of those shaking fits. Personally, I suspect stress played a massive role. Between everything happening over the last few years and the grind of college, it all just builds up, doesn't it? You might want to consider some multivitamins, plus maybe getting your thyroid and ovarian hormones checked out. And perhaps seeing a psychologist—even just for a few sessions to figure out how to manage your time, slow down, and maybe find some light recreation. A one-hour walk, rollerblading, or cycling—anything you enjoy that isn't physically punishing. For me, nothing worked better than the coast, swimming, and that salt air... now that I'm back in the city, it feels like the whole cycle is starting all over again.

Honestly, I’m dying to know how that all wrapped up.😛

I guess I know those symptoms a little too well myself, unfortunately... for me, it’s always been mostly about the anxiety.

Stumbled onto this thread, read the opening post, and my first thought was—anxiety. Just pure anxiety.

Then I kept reading the rest, seeing how everyone’s test results came back clean, and honestly? It just confirmed what I already suspected.