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Sinersul side effects: what to expect while taking antibiotics?

Started by Walter Smith8 · · 👁 4 views · 20 replies

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Participants Walter Smith8coppernomad24northernviper392Chris Morgan67Gerald Kern77Joshua Gray4redbadger26Andrew Anderson6ruggedfalcon2swiftscout8Joshua Bennett4Sam Murphy
Walter Smith8 Walter Smith8 Active MemberOP
72 messages
joined Nov 2007
#1 ·
So, I started taking Sinersul for some inflammation... and for the last three days—basically since I started—I've been dealing with these brutal headaches, dizzy spells, and nausea. The insert says these are "common side effects" and that I should give my doctor a heads-up.

The first two days were manageable, I guess, but last night was a total disaster—I almost passed out because I felt so incredibly weak...

Should I just quit taking it or push through? I really can't get a hold of my doctor right now...

Has anyone else gone through this kind of thing?
coppernomad24 coppernomad24 Member
22 messages
joined Feb 2006
#2 ·
lol, I’m just allergic to penicillin, so I don't touch
those kinds of antibiotics
coppernomad24 coppernomad24 Member
22 messages
joined Feb 2006
#3 ·
Look, I’m just going to give you some straight-up common sense advice: stop doing this RIGHT NOW.
You aren't going to drop dead instantly, but sticking with this could seriously mess you up in ways you aren't prepared for.
Just call the local ER or an on-call doctor and get some actual professional guidance.
northernviper392 northernviper392 Member
13 messages
joined Jan 2005
#4 ·
About a year and a half ago, I found out the hard way that I’m actually allergic to Sinersul.
Mine was a pretty intense reaction, too—I broke out in a rash all over my body. I stopped taking it that very same day and went straight to see my doctor.
From what I’ve heard, plenty of people have issues with Sinersul, so if you ask me, you should probably check in with a medical professional. It’s just not worth playing games with your health.
Chris Morgan67 Chris Morgan67 Member
49 messages
joined Jul 2007
#5 ·
SINERSUL IS EVIL

I have no idea who else is being prescribed this antibiotic. Last time I took it, I ended up with a horrific bladder infection; I spent a week in the hospital crying every time I had to use the restroom...
And I’m not even allergic to penicillin... It’s just that whenever I take Augmentin or Cipro, I end up with a yeast infection.

But my doctor just put me on some penicillin-based antibiotics from Klavax, and I haven't had any issues with Candida at all...
Stop asking about it online and just go see your doctor!!!!
Gerald Kern77 Gerald Kern77 Active Member
56 messages
joined Dec 2011
#6 ·
northernviper392 said:I found out about my allergy to Sinersul about eighteen months ago.
My reaction was—well, let's just say it was intense—I broke out in a rash all over. I quit taking it immediately and went straight to my doctor.
I've heard quite a few people can't tolerate Sinersul, so both you and I should probably listen to the experts here; it's best not to gamble with this stuff.

I developed an allergy to Sinersul twenty years ago... though it wasn't limited to just that—it extends to anything containing sulfonamides. The first time, it was just nausea and a rash; the second time, I couldn't breathe. I ended up in the ER, where they warned me that next time, I might not make it in fast enough. My medical records explicitly state "CAVE SULFONAMIDES," a warning I reiterate to every physician I encounter—since so many medications, even simple burn creams, contain sulfonamides.
Walter Smith8 Walter Smith8 Active MemberOP
72 messages
joined Nov 2007
#7 ·
Thanks for the input, everyone!

I actually called up my local pharmacy, and the pharmacist there told me that it shouldn't be happening because of Sinersul 😕 but if I'm really feeling suspicious about it, I should just quit taking it.

Plus, the little pamphlet says this kind of thing is totally expected 🙄

Now that I'm thinking back—it’s all a bit fuzzy—but I feel like I had similar issues when I was on Sinersul years ago (though at the time, I honestly thought it was just an adverse reaction to Sumamed 😵 ).
Joshua Gray4 Joshua Gray4 Newcomer
4 messages
joined Apr 2006
#8 ·
Well, I had such a dreadful allergic reaction after taking some Sinersul. It was quite a sight, really—this terrible redness and itching spread all over my body, and my eyes and lips even started swelling up, which was just awful 😲
I ended up needing two different antihistamine injections, which, let me tell you, was a rather chilling experience...
It turns out I’m also allergic to Sumamed, though my doctor mentioned that it’s incredibly rare since Sumamed is generally considered such an excellent medication. She explained that they actually belong to the same class of drugs.
Walter Smith8 Walter Smith8 Active MemberOP
72 messages
joined Nov 2007
#9 ·
Like I said, I finally kicked the habit yesterday... and honestly? I feel amazing. 🎉

The only thing keeping me up at night is this inflammation, though. I couldn't get a hold of my doctor over the phone today to figure out how to wrap up this whole treatment—fingers crossed the bacteria doesn't decide to throw a massive party in my system before Monday rolls around. 😢
Gerald Kern77 Gerald Kern77 Active Member
56 messages
joined Dec 2011
#10 ·
Joshua Gray4 said:I had a terrible reaction after taking Sinersul—horrible redness and itching everywhere, plus my eyes and lips swelled up. It was quite a nightmare. 😲
I ended up needing two anti-allergy injections—not exactly a fun afternoon.
I'm also allergic to Sumamed, though my doctor mentioned that’s extremely rare since Sumamed is considered such a reliable medication. Apparently, they belong to the same drug class.

Sumamed is azithromycin.
Sinersul is sulfamethoxazole and trimethoprim... based on the medical literature, they aren't even in the same class.

I have severe allergies to sulfonamides, yet I take Sumamed without any issues at all.
redbadger26 redbadger26 Newcomer
8 messages
joined Jun 2007
#11 ·
Chris Morgan67 said:SINERSUL IS EVIL

I have no idea who else is being prescribed this antibiotic. The last time I took it, I ended up with a hellish bladder infection and spent a week crying in the hospital because I couldn't even make it to the restroom without agony!
And it isn't like I'm allergic to penicillin... the only things that trigger yeast infections for me are Klavax or Augmentin.

But my doctor just put me on some Klavax penicillin antibiotics recently and I didn't get any candidiasis at all.
Stop posting about this and just go see your doctor!!!!

Just a small side note—Augmentin and Klavax are actually the exact same medication, just amoxicillin and clavulanic acid produced by different manufacturers. 🙂
Andrew Anderson6 Andrew Anderson6 Active Member
90 messages
joined Dec 2002
#12 ·
blonde_hair said:nah, I'm just allergic to penicillin so I don't touch
those kinds of antibiotics


Sinersul is a sulfonamide—so it's actually the go-to choice for anyone with a penicillin allergy!

Basically:

sulfonamides are one thing
penicillin is totally different

It’s all super individual, though. Hard to say if Sinersul is "good" or "bad" since everyone reacts differently—personally, I can take almost anything, but Amoxicillin makes me break out in hives, so I steer clear of that.

@Walter Smith8 - if you're getting side effects that heavy, I'd hit up a doctor and ask for an alternative. Stopping an antibiotic course after only three days isn't smart either; if you don't finish the whole prescription, you risk building up resistant bacteria, and then you're stuck with something that won't even work when you actually need it.
ruggedfalcon2 ruggedfalcon2 Active Member
64 messages
joined Jun 2005
#13 ·
I haven't gone through the entire thread yet, but listen up—Sinersul isn't some kind of magic cure-all... ☕
Andrew Anderson6 Andrew Anderson6 Active Member
90 messages
joined Dec 2002
#14 ·
ruggedfalcon2 said:Haven't really dug through the whole thread yet—but listen up, kids—Sinersul isn't exactly an antibiotic. ☕

I'm sorry, I didn't quite catch that. You only sent "je"—is there something you wanted to talk about? 🙂

So, Sinersul is an antibiotic—but just to be clear, it’s definitely not a penicillin-type one.
Gerald Kern77 Gerald Kern77 Active Member
56 messages
joined Dec 2011
#15 ·
Sinersul (a sulfonamide) is an antimicrobial—but it is NOT an antibiotic!

Copied from www.pharmacology.com.

"Antimicrobials are drugs used to treat and prevent bacterial infections.

Broadly speaking, we categorize antimicrobials into antibiotics and other chemotherapeutic agents—which includes sulfonamides, trimethoprim, and fluoroquinolones. Unlike antibiotics, sulfonamides, trimethoprim, and fluoroquinolones are entirely synthetic drugs; they simply don't exist in nature. Antibiotics, by contrast, are either natural products or structural derivatives of those natural substances.
ruggedfalcon2 ruggedfalcon2 Active Member
64 messages
joined Jun 2005
#16 ·
Andrew Anderson6 said:is 🙂

Sinersul IS an antibiotic, but it's NOT a penicillin-based one

🙂 Your knowledge is pretty thin here...👎 maybe try picking up a book or two.☕
ruggedfalcon2 ruggedfalcon2 Active Member
64 messages
joined Jun 2005
#17 ·
Blue said:Sulfonamides are antimicrobials, but they aren't actually antibiotics!

Copied from www.mayoclinic.org.

"Antimicrobials are drugs used to treat and prevent bacterial infections.

Broadly speaking, we categorize antimicrobials into antibiotics and other chemotherapeutic agents—which includes things like sulfonamides, trimethoprim, and fluoroquinolones. The distinction is that sulfonamides, trimethoprim, and fluoroquinolones are entirely synthetic drugs; you won't find them in nature. Antibiotics, on the other hand, are either natural products or derivatives that have been structurally modified from natural sources."

👍 ☕
swiftscout8 swiftscout8 Active Member
87 messages
joined Apr 2007
#18 ·
Look, I had a rough time with Doxycycline. Honestly, I’d probably react the same way to any tetracycline.

The first capsule didn't seem to do much damage. But about 15 or 20 minutes after the second one, the nausea hit me. It was bad... just nasty. Things settled down after that. Then came the third dose—again, maybe 15 to 20 minutes in—and my stomach just started revolting. Diarrhea, nausea, the whole bit. I stopped taking them after the third dose. Everything went back to normal pretty quickly.

It's not an allergy to tetracyclines, but they definitely wreck my stomach. There are all these warnings everywhere... take it with food, don't take it with milk, watch out for this or that. But what if I have to take it at 5:00 AM? What am I supposed to eat at five in the morning just to buffer a pill?
Chris Morgan67 Chris Morgan67 Member
49 messages
joined Jul 2007
#19 ·
salt grain said:Just a quick heads-up—Klavocin and Augmentin are actually the same thing, just amoxicillin and clavulanic acid from different manufacturers. 🙂

I figured as much, since I've ended up with another yeast infection...👎
Joshua Bennett4 Joshua Bennett4 Active Member
53 messages
joined Sep 2008
#20 ·
I've been allergic to penicillin my whole life. I actually took Sinersul once back when I was about 16 and felt totally fine. But then, when I tried it again around age 20, my tongue swelled up and turned white after just one pill... My doctor told me straight up that I'm allergic and made sure to note it in my medical records... So, there you go ☕

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