MAOI experiences

Has anyone here actually tried MAOI antidepressants? If so, how did they work for you—what were the pros and cons?

Thanks!

Not really, but from what I gather, doctors usually save MAOI for when other antidepressants just don't cut it—mostly because you can develop a dependency on the enzyme itself, plus the side effects can be a total nightmare. You should probably dig around online if you want the deep dive.

Anyway, try to stick with something else before jumping to an MAOI, if you even have the option.

So far, I’ve cycled through Prozac (portal), Faverin, Zoloft, Aurorix, St. John's Wort—I've even tried some antipsychotics like Zyprexa and Risperdal—but honestly, nothing has made a dent. From what I can tell at this point, the only things left that might actually work are Parnate or Nardil (MAOI). It's true they're usually considered a last resort, but for me, they really are the final option since I've tried so much stuff and nothing has worked.

Look, if you just hop on Google and search "MAO inhibitors," you'll get a massive pile of links. Here's one that actually mentions those two specific ones you were asking about...

Hopefully this helps (link and info on MAO inhibitors)