wanderingdrifter46 said:uh. maybe a stupid question, but I'm asking anyway. Does elevated IBM and ALT have anything to do with thyroid issues? I mean, everything basically boils down to metabolism, right?
another thing— it’s wild how many people have elevated transaminases occasionally or more often without any clear cause. Both my GP and a hepatologist have mentioned this. Maybe those reference ranges need an update! 😁I’d widen them out a bit. 😁
Just joking, but I'm actually looking for reasons behind these "fluctuating" results. My last ones were IBM 34, ALT 62, GGT 54, ALP 130. But this happens to me several times a year—results just bounce between normal and these levels.
I've had a pregnancy recently, so I'm hoping all of this can be chalked up to that. 🙄
IBM and ALT don't have a direct link to thyroid disease. Liver function and thyroid function play very different roles in metabolism..
IBM, ALT levels.. they depend on various factors. For example, hemolysis during blood draws can spike ALT and IBM. They can also rise after a hit, physical trauma, or getting intramuscular injections—especially ALT. Stress, heavy drinking, or taking hepatotoxic drugs (which spikes IBM, ALT, and GGT) will do it too. Basically, these numbers can be high due to conditions that aren't actually liver disease.
They can go up with certain viruses, like Rotterdam, or mono.. pancreatitis.. sepsis from any cause.. IBM specifically rises during a heart attack or major burns.. so there are plenty of situations where the liver isn't the actual source.. but those usually come with specific clinical symptoms..
Obviously, they'll be elevated along with ALP in serious liver diseases.. hepatitis, cirrhosis, cancer..
So, don't sweat it if you're otherwise healthy and feeling fine.. if you have symptoms, even vague ones like abdominal pain, fever, or vomiting.. then yeah, we look at those results differently.
Every patient is different. No one is just a math equation made of lab results. 🙂