Anyone have experience with Crespin gel injections?

Hey everyone,

Anyone here actually tried Crespin gel injections? My doctor’s pitching it for osteoporosis and cartilage repair—basically saying it helps rebuild things. It’s pretty new on the market here, so my insurance won't touch it. One syringe gets you $500 and lasts about 6-8 months. There's also a $2,500 version meant to last a year, but I can't find much solid info online. Don't really wanna buy a pig in a poke, especially since it's a massive chunk of change...

If anyone has some advice or has dealt with this stuff before, hit me up 🙂

Anyway, enjoy being mobile while you still can (my knees have officially quit on me ^_^)

I had my first Crespin gel injection in my left knee exactly 10 days ago. I'm 42—diagnosed with patellofemoral chondromalacia. The injection itself didn't hurt at all, despite what the doctor warned me to expect. Within two hours, the leg swelled up, though there was no pain (probably because the knee wasn't actively inflamed at the time). That swelling—or rather, the tightness—started to subside after about 3 or 4 days.
After that, I started feeling some relief in terms of better mobility. My doctor mentioned the effects would kick in around the 10-day mark, and it looks like he was right. I can put weight on it now, though I'm still playing it safe until I know for sure. I'll keep everyone posted as things progress.

Three months ago, I was out running regularly—now my knee is completely shot. To make matters worse, three days ago the other knee started acting up too. I’m waddling around like a duck, and even basic stuff—like just stepping into a bathtub—is a massive struggle.

Looks like running is officially off the table for me.

Unfortunately, about a month and a half after getting the injection, I have to say it’s had little to no effect on my left knee. My right one calmed down slightly, so I started using electrostimulation on my quads—along with some specific non-invasive exercises and riding a stationary bike with the seat cranked up super high and very low resistance (since I'm 6'3", if you can believe it). I'm still fighting an uphill battle just to regain mobility. So far, the electrostimulation has actually been the most helpful thing because it really helped reduce the stiffness in my legs. For anyone interested, check out this site:
http://www.viviangrisogono.com/index...knee&Itemid=69

From what my doctors have told me so far, there's basically no benefit here. When you're dealing with patellar chondromalacia, you really have to fight your own battles—figuring out your limits and adjusting, or honestly, completely overhauling your entire lifestyle.

It’s been nearly three months since my Crespin gel injection, and if I had to pinpoint a win—it’s that my knee hasn't flared up again during this window. In the meantime, an MRI picked up a little blister on my patellar cartilage (Grade 1-2 chondromalacia—which can be pretty painful, and clearly, the gel isn't a magic fix for that). Still, by strengthening the muscles, I’m finding I can lean on my left leg more, and it feels like my body is slowly patching up that little injury on its own. What used to be a sharp pain whenever I walked down stairs has mellowed out into a duller, less intense ache. My doctor just tells me to stay patient. As for my other knee, it calmed down quickly—maybe ten days—and felt fine for a while, but now it’s starting to act up again. Dealing with chondromalacia seems to be a bit of a waiting game...

Bumping this thread. Has anyone had any recent experience with this? My mom is 75, and her doctor is recommending this gel for her knee osteoarthritis. He even brought up the possibility of surgery. Apparently, when looking into this stuff over in Germany, they hadn't even heard of it.

I’m gonna ask this again because I really need some insight: has anyone actually had good luck using Grespin gel? It comes in injection form. I’ve got a 75-year-old in my life, and her orthopedic surgeon told her to go pick some up and bring them back so he can inject them directly into her aching knees. He’s claiming it’ll basically regrow the cartilage and kill off the pain.
The price tag on this stuff is roughly $280 here in the States. From what I hear, you’d be paying pretty much the same amount over in Germany, too.
I’d really appreciate it if anyone who’s actually used this stuff could give me the lowdown. Is it legit, or am I just throwing money down the drain?
Thanks in advance!

Taylor Robinson8 said:I want to ask again: has anyone actually had a positive experience with Gillette gel? It’s being released as an injectable treatment. An orthopedic surgeon recommended it for a 75-year-old woman, advising her to purchase it and bring it to his office so he can inject it directly into her painful knees. He claims it will regenerate the cartilage and stop the pain altogether.
The price for this stuff here is roughly $280. I’ve heard the cost in Germany is about the same.
I would truly appreciate it if any actual users of this product could explain whether there is any real benefit here, as I don't want to throw money down the drain.
Thank you in advance

It is often claimed that Crespin gel, which is hyaluronic acid-based, can assist with advanced degenerative osteoarthritis involving joint pain and limited range of motion. Essentially, it acts as a lubricant to grease the joints, which may provide temporary pain relief and improved mobility for a specific window of time. However, the claim that it will "regenerate" cartilage is simply false. Cartilage regeneration is a massive global challenge in medical science; while significant research is ongoing and some progress has been made, it is far beyond the capabilities of Crespin gel.