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Lab results - looking for opinions [PLEASE READ 1ST POST]

Started by vividsailor7 · · 👁 44 views · 3.9K replies

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Kevin Garcia12 Kevin Garcia12 Active Member
52 messages
joined Jun 2010
#501 ·
Sure enough
Amy Torres6 Amy Torres6 Newcomer
4 messages
joined Feb 2011
#502 ·
So, I'm looking at my discharge papers from the hospital here.
........labor was induced because the CTG looked sketchy, then they had to go in for a C-section since things weren't progressing. Also, the amniotic fluid was meconium-stained. ABS: pH 7.266, B.E. -12.9
I'm trying to figure out what that bolded part actually means?
Thanks for the help
Kevin Garcia12 Kevin Garcia12 Active Member
52 messages
joined Jun 2010
#503 ·
Amy Torres6 said:So, I'm looking at my discharge papers from the hospital after giving birth, and there's this note written on them...
So, the labor ended up being induced because the CTG looked pretty sketchy and pre-pathological... then everything just went south and we had to finish things via C-section since progress completely stalled out. To top it all off, the amniotic fluid was meconium-stained... So, looking at my latest labs... the blood gas results just came back and they aren't exactly what I was hoping to see. My pH is sitting at 7.266, and the base excess is down at -12.9... which definitely feels like things are a bit out of whack on the metabolic side...
I was wondering... what exactly is that bolded part supposed to mean?...
Thanks for getting back to me...

It’s most likely an ABS analysis from the baby's umbilical cord blood, which would probably point toward moderate acidemia in this situation, but since there isn't any specific info on where exactly that sample was pulled from, we're really just left with speculation... 🤷

TheChloee's said:I'm not entirely sure where else to dump this, so I really hope you guys don't mind me popping in here... Anyway, a buddy of mine just got his PET/CT results back and he's telling me this:
There’s absolutely no sign of abnormal glucose metabolism in the retroperitoneal lymphadenopathy area that would clearly point to any malignant activity... and I don't see any pathological metabolism in the other lymph node basins either, nor in the spleen or the bone marrow...
Since there's no sign of significant lymphadenopathy, we really need to dig deeper and evaluate those nodes further... It’s possible we could be looking at a low-grade lymphoma, especially since the PET scan didn't show any metabolic glucose activity elsewhere in the body that would point toward an active malignancy...
So, looking at this conclusion, he’s got swollen lymph nodes all over his body, and the report actually specifies the size and shows them in the images; now, keep in mind his grandmother had leukemia, and then last year he suddenly came down with a pulmonary embolism and that's when everything just started spiraling downhill... only for the doctors at the local county hospital to insist for two whole months that nothing was wrong, eventually sending him home with nothing but some Advil and Tylenol, while meanwhile the thrombosis took hold of his leg and now he's stuck on crutches... they ended up having to go out and get their own testing done because, obviously, he clearly wasn't getting any real help...

So, what's the actual question here...?
Amy Torres6 Amy Torres6 Newcomer
4 messages
joined Feb 2011
#504 ·
Kevin Garcia12 said:It’s probably an ABG analysis from the baby's umbilical cord blood—which, in this specific scenario, would likely point to moderate acidosis. But honestly, since they don't explicitly state where that sample was pulled from, we're all just playing the guessing game here... 🤷

The sample is umbilical cord blood. So, what exactly is acidosis, and what does it actually mean when this happens during a C-section? What was the trigger for the acidosis? Was it hypoxia?
The kid has Grade II brain bleeding (left side) and hypertonus dystonia syndrome. He’s almost 3 months old now.
Thanks for the input.
Nicholas Myers Nicholas Myers Active Member
163 messages
joined Jan 2012
#505 ·
TheCloee's, your post has been moved to the thread PET/CT - interpreting results.
Kevin Garcia12 said:And what exactly is the question?

Please keep any further discussion regarding PET/CT findings within the designated thread. Thanks for understanding.
Kevin Garcia12 Kevin Garcia12 Active Member
52 messages
joined Jun 2010
#506 ·
Amy Torres6 said:The sample is the baby's umbilical cord blood. What exactly is acidemia, and what does it imply in this specific case occurring during a C-section? What was the trigger for the acidemia? Was it hypoxia?
The baby has Grade II brain bleeding (left side) and hypertonus dystonia syndrome. He’s almost 3 months old now.
Thanks for the reply

Basically, if we're looking at hypoxia being the culprit, then acidemia—or acidosis—essentially means the blood pH has shifted toward the
"acidic" side (lower than physiological norms). Granted, preemies and even full-term babies have their own little quirks, and a generally healthy newborn can handle quite a bit when it comes to oxygen levels and electrolytes, plus their "normal" blood work looks a bit different than ours adults, but I'm pretty damn sure we're talking about a pathological value here...
Since this isn't my primary field of expertise, if you want a 100% airtight interpretation, you really ought to talk to a neonatologist, but based on everything described, it's logical to assume hypoxia was involved... because the meconium, that low pH paired with a heavily negative Base Excess, and those CTG changes are all classic hallmarks of fetal distress, which acts as a prognostic sign for complications and potential damage. In any case, opting for a C-section was definitely the right call, though whether they should have jumped into surgery sooner or avoided attempting a vaginal delivery altogether (assuming it wasn't an unplanned emergency) is something I won't weigh in on, since I'm not an OBGYN...
Hypoxia was clearly present even before the surgery started, and that’s what caused the meconium-stained amniotic fluid and those CTG shifts that triggered the decision to go in for the section in the first place...
Amy Torres6 Amy Torres6 Newcomer
4 messages
joined Feb 2011
#507 ·
Kevin Garcia12 thanks so much for getting back to me. Honestly, looking back, there was an 11-hour gap between that pre-pathological CTG reading and the actual autopsy—so yeah, we probably could have just skipped the games and gone straight to the autopsy instead of trying for a vaginal delivery. But look, both the doctor and I had already made up our minds to try the vaginal route. We didn't know about the meconium until the autopsy happened, because my cervix stayed completely shut the entire time during induction. If an amnioscopy had been possible and we’d seen meconium-stained fluid, neither the doctor nor I would have even considered attempting a vaginal birth.
The baby had an Apgar score of 10/10.
Seriously, thanks again for such a quick and thorough response.
Casey Cooper49 Casey Cooper49 Member
15 messages
joined Oct 2009
#508 ·
Hey everyone, looking for some help and your take on this.
I'm 45, 86 kg, and hit the gym occasionally. I was lifting weights and taking L-Carnitine the night before my blood draw. This morning, I got these results back, and a few things are high:

aspartate-aminotransferase - 37
alanine-aminotransferase - 68

Cholesterol - 6.9
LDL cholesterol - 4.6...
Everything else seems normal, though I'm dealing with a cold and allergic rhinitis right now, so I've been using Avamys spray....

thanks
wiredsailor46 wiredsailor46 Newcomer
1 message
joined Mar 2013
#509 ·
Can someone help me make sense of these blood work results? My doctor is away on vacation, and frankly, I don't have the patience to sit around waiting for his return :
WBC 4.9
LYM% 25.4
MON% 5.5
GRA % 69.1
LYM# 1.20
MON# 0.20
GRA# 3.50
RBC 4.43
HGB 136
HCT 0.386
MCV 87
MCH 30.7
MCHC 352
RDW 13.3
PLT 233
MPV 6.6
PCT 0.153
PDW 14.8

For context, I had this done because I've been dealing with some hives...
Kevin Garcia12 Kevin Garcia12 Active Member
52 messages
joined Jun 2010
#510 ·
Casey Cooper49 said:...was taking L-Carnitine, had blood drawn this morning and these are the values that came back elevated:

aspartate-aminotransferase - 37
alanine-aminotransferase - 68

Look, these are only slightly elevated, so it’s honestly tough to pinpoint why because liver enzymes can be pretty "reactive" when you're messing with various supplements—like Carnitine, for instance. I don't know the exact degree of their impact, they could definitely be causing it, but realistically, anyone dealing with this on a daily basis would have a better handle on it... it's possible it's due to that, but it doesn't have to be...

Casey Cooper49 said:Cholesterol - 6.9
LDL cholesterol - 4.6....
all my other values are within the normal range, even though I'm feeling a bit under the weather with a cold and some allergic rhinitis that has me using Avamys spray....

Your cholesterol and LDL are high, quite high actually, and while the AHA/ACC has lowered the "alarm threshold" a few times over the years, this is definitely outside the guidelines no matter how you look at it...

wiredsailor46 said:Can someone help me interpret these blood results? My doctor is on vacation and I really don't have the patience to wait until they get back:
WBC 4.9
LYM% 25.4
MON% 5.5
GRA % 69.1
LYM# 1.20
MON# 0.20
GRA# 3.50
RBC 4.43
HGB 136
HCT 0.386
MCV 87
MCH 30.7
MCHC 352
RDW 13.3
PLT 233
MPV 6.6
PCT 0.153
PDW 14.8

I had the tests done because of some hives that keep breaking out....

There is nothing to interpret here; these results don't say a single thing that would shed light on the cause of your hives, and frankly, since there's no differentiation of granulocytes into Eo/Ba/Ne to help identify an existing allergic tendency, it's twice as useless for that purpose...
Casey Cooper49 Casey Cooper49 Member
15 messages
joined Oct 2009
#511 ·
Kevin Garcia12 said:It’s slightly elevated, but it's hard to pin down why. Liver enzymes can be pretty reactive to various supplements—like carnitine, for example. I don't know exactly how much impact they have, but they could play a role, or maybe not. Honestly, someone who deals with this daily would have a better idea. It might be the supplements, or it might be nothing at all...

Cholesterol and LDL are quite high. The AHA/ACC has lowered the "alarm threshold" a few times now, but these numbers are definitely outside the guidelines regardless of which option you look at...


Kevin Garcia12 thanks so much... As a complete outsider here, I'm asking how many hours should I fast before a blood draw to get an accurate reading? In the meantime, I just remembered I had some French toast late in the afternoon the day before. Then, after hitting the gym around 11 PM, I had a protein shake (I had my blood drawn early the next morning)... Either way, I’ll have to redo the blood work.🙂
Kevin Garcia12 Kevin Garcia12 Active Member
52 messages
joined Jun 2010
#512 ·
It’s a tough call, really, because it all depends on just how intense someone's triglyceride and cholesterol utilization actually is... normally, a 24-hour window gives you a pretty solid snapshot of what's going on, but when you're dealing with certain enzyme function issues—whether that's something you were born with or something you picked up along the way—even the most hardcore, disciplined diet plans can fail to "chase" those numbers back down into the normal range. In any case, everyone knows that your diet is basically the boss of your triglyceride levels, but for everything else in that lipid panel, you're looking at a tug-of-war between what you eat and how your liver produces stuff... basically, if you're genetically predisposed to high cholesterol, you could stop eating every single gram of fat on the planet and your levels would still stay high because your liver is just going to synthesize it anyway...

As for the AST and ALT, honestly, practically anything can push those upward, and they are such incredibly non-specific markers when it comes to signaling that something is actually happening with the liver from a metabolic and cellular standpoint...
Donna Nelson71 Donna Nelson71 Newcomer
1 message
joined Mar 2013
#513 ·
Could you please clarify what the CRP and ALT levels indicate in these lab results?

(DEPARTMENT OF HEALTH STUDIES, MLD-I.M.)
Gary Diaz75 Gary Diaz75 Newcomer
5 messages
joined Apr 2013
#514 ·
So, I just got my first blood concentration test back for Lamotrigine, and the result shows 12.5 umol/L. Since the therapeutic range is supposed to be anywhere from 4 to 55... I'm honestly stuck. Is this actually okay, or is it way too low?

For context, I'm 21 years old and currently on Arvind 150 mg daily.
vividsailor7 vividsailor7 Active MemberOP
217 messages
joined Sep 2011
#515 ·
Gary Diaz75 said:So, I just got my first blood test for lamotrigine levels back, and the result shows 12.5 umol/L. Since the therapeutic range is supposedly between 4 and 55, I can't figure out if this is actually fine or if it's way too low?

For context, I'm 21 and currently taking Arvind 150 mg daily.

The lab result itself is fine, but let’s be real: the actual number on the paper matters far less than how the patient is actually feeling clinically.

Donna Nelson71 said:Can someone explain what CRP and ALT mean on these results?

(DEPARTMENT OF HEALTH STUDIES, MLD-I.M.)

ALT stands for alanine-aminotransferase, which usually flags liver issues.
CRP is C-reactive protein, essentially a marker for inflammation.
Jason Cox5 Jason Cox5 Newcomer
2 messages
joined Sep 2012
#516 ·
Can someone walk me through these H. pylori immunoenzyme test results? I've got IgG coming in positive at 142 U/ml... but the IgA is negative. What does that actually mean?
neonheron32 neonheron32 Member
13 messages
joined Mar 2013
#517 ·
So, here’s the short version:

Female, 26 years old. I was scheduled for laparoscopic surgery to deal with endometriosis on my left ovary. They pushed the procedure back because of a suspicious ECG—not to dwell on it, a follow-up heart ultrasound confirmed everything is fine, just an atypical ECG—and something on my thigh that looked like a hematoma that wouldn't clear up. Regarding that last bit, I'm still running final tests, but an ultrasound showed it’s actually lymphedema in the fatty tissue, which is responding to Elocom.
What I’m really looking at are the blood results. The first set was done prep for the surgery, and every single value was within the normal range except for the white blood cell count.

Lymphocytes were 13% (ref: 20-46), and segmented granulocytes were 77% (ref: 44-72).

After they looked into the "hematoma," they ran a much more detailed blood panel. My Hematology specialist—who is truly top-tier, and I have immense respect for her because she handled a family member's case brilliantly—said the findings aren't bad.

Anyway, I’m only listing the values that deviate from the norm since the full report is massive and it’s a hassle to photograph the whole thing right now.

MPV 10.6 (6.8 - 10.4)
Lymphocytes 0.92 (1.19 - 3.35)
though the lymphocyte percentage is back to normal now (25%)

PT - INR 1.16 (2.0 - 3.5)

Urea 2.5 (2.8 - 8.3)

GGT 7 (9 - 35)
ALP 37 (54 - 119)

From the serum protein electrophoresis:
Total proteins 85.4 (66-81)

Hematology noted this is a state of mild leukopenia (White blood cells were 3.59). I did have a virus a few days before this second blood draw (severe sore throat, slight fever, and sinus issues).

To be honest, those low lymphocyte numbers are what actually spooked me. I've heard that if these enzymes are low, it doesn't matter, but everywhere you look, the explanation for low lymphocytes is some terrible disease.

Should I be worried, or can this just pass as a normal result?

I don't really have any major symptoms; my immunity is decent. I catch a little bug every winter, but nothing long-lasting or heavy, and nothing involving the lower respiratory tract... I wouldn't say I stand out from the crowd in that regard.

If I need to show the full report, I can scan it at work.

Thanks in advance 🙂
velvetmoose9 velvetmoose9 Active Member
163 messages
joined Apr 2020
#518 ·
Gary Diaz75 said:So, I just got my first blood test back to check my lamotrigine levels, and it’s sitting at 12.5 umol/L. Since the therapeutic range is supposedly somewhere between 4 and 55, I'm honestly stuck wondering if this is actually fine or if it's way too low?

Just for context, I'm 21 and currently on Arvind 150 mg daily.

Like vividsailor7 already pointed out, the most important thing here isn't the number itself, but how you're actually feeling clinically.
I'm guessing this medication was prescribed to help manage some kind of seizure activity—maybe related to bipolar disorder.
We really don't know what prompted the decision to check these levels in the first place:
-was it just a routine checkup?
-is the medication not doing its job (like, the seizures aren't stopping)?
-did an EEG come back showing something weird even though you feel okay, or maybe a clean EEG while things are actually getting worse?
-or something else entirely?
Gary Diaz75 Gary Diaz75 Newcomer
5 messages
joined Apr 2013
#519 ·
velvetmoose9 said:Like @vividsailor7/">@@vividsailor7 already pointed out, the clinical picture is what actually matters here.
I’m guessing this medication was prescribed to manage some kind of seizure activity—maybe related to bipolar disorder.
We have zero clue why they even bothered checking the drug concentration level in the first place:
- just routine monitoring
- the meds stopped working—no effect on the seizures anymore
- an abnormal ECG despite looking better clinically, or conversely, a normal ECG while things are clearly getting worse
- or something else entirely?

Yeah, so after going a full year without a seizure, I had a grand-mal episode. My doctor bumped up my dosage and ordered this lab work. Other than that, I've been doing fine for the last three months since that seizure—no episodes. I've got an EEG scheduled in two weeks, so we'll see how it goes...
Angela Nelson3 Angela Nelson3 Newcomer
1 message
joined Mar 2013
#520 ·
Hey guys, could someone please help me out? I'd love to get some thoughts or even just a quick explanation of these results!
My ACL antibodies came back negative! 🙌✨
My anti SS-A/Ro came back at 0.80, while the normal range is 0-15. So, I guess I'm totally in the clear! Fingers crossed!
My anti SS-B/La came back at 2.70, while the normal range is 0-15. Fingers crossed everything is totally fine!
Anti Jo-1 at 1.00! Still hanging in there!
Anti Scl-70 came back at 2.00! Fingers crossed, everyone! 🤞✨
My anti RNP/Sm came back at 5.60! 😅 Keeping my fingers crossed!
ANA-ELISA 21
Everything's within range! All the values are 0-15, except for that last one which goes up to 55.
I'd love to get some input on this! Any ideas on what might be going on? An immunologist sent me in for more testing because they're suspecting some kind of autoimmune issue.

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