Lab results - looking for opinions [PLEASE READ 1ST POST]

crimsonfox26 said:Hi, I have a question regarding a stool analysis for parasites.

What parasites are we talking about here?

On this... I don't have the link. Please provide it. Here is the breakdown of what stool testing actually covers.

restlessangler said:Picking up where I left off above:

Cytology results from the puncture smear show numerous lymphocytes, follicle center cells, a few histiocytes, and some small clusters of glandular epithelium from skin adnexa (possibly sweat glands?). Impression: lymphocytic proliferation.

Can you translate this? 😬

In short: the cytologist didn't give a definitive diagnosis. He simply reported what he saw—clearly, there was an increase in lymphocytes forming the structure of the lymph node. However, he stopped short of describing the specific appearance of those lymphocytes or offering his clinical impression of what might actually be going on.

Dana Wilson33 said:My gynecologist sent me for blood work because I’ve been on birth control pills. I'm in my late twenties.
The values that have increased,
MPV 11.1 H / 6.8–10.4 / normal values
Neutrophil granulocytes 35.9 L /44-72/ normal value.
Lymphocytes at 51.0%—high relative to the 20-46% range.
Lymphocytes 3.42 H /1.19-3.35 / normal values
Everything else falls within the normal range.

Could you please clarify what this is about? Thanks.

It’s difficult to offer any meaningful commentary without knowing your white blood cell and platelet counts, or seeing a complete differential CBC Panel.

Betty Gray36 said:What does it mean when an HLA typing report shows "HLA-B 35 ND"?

As you can see, each HLA type consists of two alleles, resulting in two separate numbers. You inherit one HLA from your father and the other from your mother. In your case, you have one HLA-B identified as 35, while the second HLA-B remains undefined. What was the motivation behind running this specific test?

Elizabeth White48 said:Any thoughts on this part of the lab results?

Why such an extensive endocrine workup? I suspect it isn't "just" Hashimoto.

My diagnosis is Rea, so that’s why. I wonder if that 35 is connected to that?
thanks for the reply 🙂

HLA-B35 isn't linked to an increased frequency of reactive arthritis; that would be HLA-B27.

I decided to look into this because my knee was swelling up all summer—they had to drain 60ml from it the first time, then a bit less later on—and on top of that, I’ve been dealing with pains in my ankles and back.

Maria Fisher46 said:What’s the white blood cell count?

High eosinophils on their own don't mess with growth, but having elevated levels can be a side effect of various underlying issues that might impact how someone grows.

Something like atopy could show up as an increase in eosinophils, and you definitely have to consider things like parasitic infections or other medical conditions too.

The total white blood cell count came back at 15.41 (with the normal range being 6-16), so everything else in the CBC Panel looks totally fine.
We finally got the referral for a sweat chloride test, so now we're just sitting here crossing our fingers and hoping for the best.

Maria Fisher46 said:To put it simply—the cytologist didn't really give a definitive opinion on what we're looking at here. They just noted what they saw... which is clearly an increase in lymphocytes, since those are what make up the lymph node in the first place. However, they didn't go into any detail about the actual appearance of those lymphocytes or offer a professional impression of what might be going on behind the scenes...

So, what does this lymphocyte prolif...

Betty Gray36 said:I went in for testing because my knee swelled up this summer (first they drained 60ml, then a bit less later), along with pain in my ankles and back..

Even if you aren't positive for HLA-B27, you can't rule out reactive arthritis. It’s entirely possible for someone without the HLA-B27 marker to develop it.

Emily Ortiz27 said:Total white blood cell count is 15.41 (ref range 6-16); everything else in the CBC Panel is within normal limits.
We got the referral for a sweat chloride test and we're just crossing our fingers.

The math shows the child has 3,544 eosinophils/µL, which points to moderate (mid-range) eosinophilia.

With chronic allergies—which your history seems to suggest—eosinophil counts usually stay below 2,000/µL.

The test being run (sweat chloride) is used to screen for Cystic Fibrosis, which isn't directly linked to eosinophilia. So, regardless of what the chloride levels show, we still need to figure out the cause of the eosinophilia itself.

restlessangler said:What does that lymphocyte proliferation thing mean...

Lymphocyte proliferation means an increase in the cells that make up the lymph nodes. That finding is expected; the real question is why they are proliferating and what the characteristics of those specific cells are. The cytology report didn't provide much detail on that front.

Maria Fisher46 said:Lymphocyte proliferation—basically, those cells that build up the lymph nodes. Honestly, seeing lymphocyte proliferation isn't surprising in itself... what we really need to pin down is *why* they're multiplying and what specific characteristics those proliferating cells actually have. Unfortunately, the cytology report didn't go into any detail regarding that aspect.

So, I’m going to proceed under the assumption that everything is fine, especially since the immunologist hasn't ordered any follow-up testing...

Thanks so much for the reply, Felix!

He didn't suggest any further testing because, based on my history and clinical presentation, it looked like a standard part of your underlying condition. Plus, the Abdominal Ultrasound showed the lymph nodes aren't even significantly enlarged. 🙂

Hello everyone.
I’m reposting this because I’m honestly not sure if I should be looking in a different thread or elsewhere—does anyone here have the expertise to help me make sense of these results? I gave birth to my third child about a month ago, and since the delivery, I’ve been dealing with this nagging pain and general discomfort under my right rib cage. I went in to get some blood work done specifically because of it, and for the most part, everything looks perfectly standard, with a few exceptions:
MPV 11.1 (6.8-10.4)
Urate 391 (134-337)
CRP 6.1
And then there's the urine analysis:

Color - colorless
pH 5.5
Bilirubin 0
Urobilinogen 10
Glucose 0
Ketones 0
Protein 0
Erythrocytes 10
Leukocytes 500
Nitrites 0
Urinalysis via fluorescent flow cytometry:
Leukocytes 31
Epithelial cells 6
Fungi 3
Bacteria: many.

Interestingly enough, the urine culture came back sterile...
Over the last month, I've already had to take three different courses of antibiotics to deal with phlebitis and an inflamed Bartholin's gland. Now, I'm staring at these urate levels and wondering what on earth they actually signify. Is there anything I should be doing about it? And is it even possible for these levels to be thrown off by the physical toll of childbirth? My doctor did give me a referral for an Abdominal Ultrasound, but I won't be able to get that scheduled until December... thanks.

Dear,

There is no need to repeat your post, especially since you already asked this within the hyperuricemia thread.

Statistically speaking, your urate levels are elevated, but they aren't high enough to be genuinely concerning. Crystals that lead to gout or kidney stones typically don't start forming until you hit about 420 µmol/L. Because of that, I wouldn't link that pain under rib cage on your right side to a slightly high urate level. It seems more likely to be something related to the gallbladder, which can act up after childbirth—which is probably why you were referred for an Abdominal Ultrasound.

It would be wise to make some dietary adjustments; you can find more specifics on this page.

You didn't list all the tests you've had done, but I assume your liver and kidney function panels, electrolytes, lipid profile, and fasting glucose all came back normal?

If you are looking for more detailed insight regarding abdominal pain, it might be better to post your question in the Pain under rib cage thread. There's a chance a gastroenterologist might stop by there.

Thanks so much for the response. Based on those results, a CMP was performed, and everything looks perfectly normal here:
Creatinine 61 (49-90)
eGFR >60
Uric Acid 391 (134-337)
Total Bilirubin 9 (3-20)
AST 20 (8-30)
ALT 25 (10-36)
GGT 17 (9-35)
ALP 108 (54-119)
AMS 52 (23-91)
CRP 6.1
I’m honestly not sure if this covers all the specific tests you were assuming I had already undergone.
Thanks

My gastroenterologist sent me off to get an anti-tTG and total IgA checked out, and the result came back at 2.00
The reference range says negative if it's
less than 20, and positive if it's
over 20. There’s also this little note about euroimun I-2P

Is this looking okay?

If someone could be a decent human being and help me make sense of these kidney results (sent by my dear mom)

First page

TSH - result = 1.20 > reference range 0.3-3.6 mIU/L

Second page

anti-Tg (tgaAT) - result = reference range 5-100 ui/ml
anti-TPO (MsAT) - result = 1 > reference range 1-16 IU/ML

Thanks

Everything looks totally fine with her

Chris Howard3 said:I'm not sure if all of this stems from the tests you assumed were already completed.
Thanks.

More or less. My previous response still stands.

Maria Gray45 said:My gastroenterologist ordered an anti-tTG and total IgA test. The result came back at 2.00.
The referral results came back negative—values sitting below 20.
Positive >20.
There's also a note regarding Euroimmun I-2P.

Is that alright?

What was the IgA level?

Maria Fisher46 said:Pretty much. My previous answer still stands.

What's the IgA level?

This is literally all I wrote down from my notes.

Maria Fisher46 said:Could someone please take a look at my hormone panel?

Estradiol 70 pmol/L 20 - 240
LH 5.0 IU/L 1 - 8
FSH 6.0 IU/L 2 - 10
Prolactin 16.1 μg/L 4 - 18
Total Testosterone 9.8 nmol/L 10 - 28
Free Testosterone 301.4 pmol/L 174 - 729

Percentage of free
testosterone 3.1 % 1.0 - 2.7

SHBG 19 nmol/L 15 - 100

What might an elevated percentage of free testosterone indicate?
I should mention that my libido feels perfectly fine.

Why was the testing done?

Suspected gynecomastia.

Maria Gray45 said:I'm just transcribing exactly what I wrote down.

If the total IgA is normal, then a result like this is also fine. Essentially, when diagnosing Celiac disease, the test relies on measuring specific IgA-class antibodies, which makes the concentration of total IgA vital. If total IgA levels are low, this test could yield a false negative.

Justin Garcia7 said:Suspecting gynecomastia.

In your case, there’s a bit of a mismatch: total testosterone is slightly low, while free testosterone sits within the normal range. Typically, you'd expect these two values to align. It's worth noting that in many US labs, measuring total testosterone is more reliable than measuring free testosterone and SHBG.