Lab results - looking for opinions [PLEASE READ 1ST POST]

electricmarlin62 said:Thanks for getting back to me... I was just looking over my old blood work—my Lymphocyte levels have always been elevated (right around when the Hashimoto's started). If you don't mind, could you clarify
Which value represents the absolute Lymphocyte count so I know what to track? Is it the one marked with the percentage, or something else?
Thank you so much.

The absolute count is the number that is NOT expressed as a percentage.
Best regards. 🙂

Sandra Vaughn50 said:When I say absolute, I mean the number isn't expressed as a percentage.
Hey there. 🙂

Thanks so much
Just one more thing though... back when this photo was taken http://s723.photobucket.com/user/luc...t=3&o=1..I actually had a nasty abscessed tooth—like a pulp infection—so I was wondering if maybe that could be linked to all this?

electricmarlin62 said:Thanks so much
Just one more thing—back when this scan was taken http://s723.photobucket.com/user/luc...t=3&o=1..I actually had a nasty, purulent tooth infection—an abscessed nerve—so I was wondering if there might be some connection there.

Not really. If a bacterial (purulent) infection were showing up in the blood, the lab results would look quite different—but I won't get bogged down in unnecessary technical details.

Sandra Vaughn50 said:Not really. If you could actually "see" what was happening in the blood, a bacterial infection would show up looking totally different (not gonna get into all the boring technical stuff though).

Alright.. thanks a ton for the answers everyone... Cheers

So, two weeks ago I went ahead and had these two moles removed because they were looking suspicious and changing shape on me. Now I’m just sitting here wondering if someone can explain what on earth "showing maturation" actually means while I wait for my follow-up appointment next week. I'll just type out the main bits from the report here...

Specimen 1: skin excision measuring 0.6x0.3x0.2 cm containing a dark brown lesion 0.2 cm in diameter
Specimen 2: skin excision measuring 1.3x0.7x0.5 cm containing a grayish-brown lesion 0.7 cm in diameter

Pathology Report:
1) Histologically, the lesion consists of an acanthotic epidermis with elongated epidermal ridges and darkly pigmented basal keratinocytes, along with nests of nevus cells within the basal layers of the epidermis and the underlying dermis where they show maturation. The described lesion does not reach the resection margins marked by tissue stain.
The same stuff applies to the second mole too, including the pathology diagnosis listed below.

Pathology Diagnosis: compound lentiginous nevus

They told me everything looks fine, but I'm still stuck on this whole "showing maturation" phrase. Anyone? Thanks in advance! 🙂

amberpanther25 said:Two weeks ago, I had two moles removed—they were looking suspicious and changing shape. I'm just trying to understand what they mean by "showing maturation" before my follow-up appointment next week. I'll list the main details from the report here.

Specimen 1: Skin excision measuring 0.6x0.3x0.2 cm containing a dark brown lesion 0.2 cm in diameter
Specimen 2: Skin excision measuring 1.3x0.7x0.5 cm containing a grayish-brown lesion 0.7 cm in diameter

Pathology Report:
1) Histologically, the lesion consists of an acanthotic epidermis with elongated epidermal rete ridges and darkly pigmented basal keratinocytes, along with nests of nevus cells in the basal layers of the epidermis and within the underlying dermis where they show maturation. The described lesion does not reach the resection margins marked by tissue staining.
The same applies to the second mole and the pathology diagnosis listed below.

Pathology Diagnosis: lentiginous composite nevus

They told me the results look fine, but I'm curious about this phrase regarding "maturation." Thanks in advance! 🙂

It means the cells are mature—which, in this context, is a good thing.
It’s the immature cells we actually worry about.

Hey there... I'm 27, and I've been dealing with hypothyroidism for almost a year now. We've been trying to conceive for nearly a year, but nothing is happening. We've gone through every possible gynecological exam you can think of, and everything looks perfect on that front. My husband's side of things is totally fine too.
I've had several blood panels done over the last year. My doctor keeps telling me that everything is within the normal range. I even saw an infectious disease specialist, who basically just told me to keep monitoring my blood work. But honestly? I can see some deviations here, so I was hoping you all might be able to take a look at them for me...
First blood panel, - - - Second blood panel
Leukocytes 8.3(3.4-9.7) - 8.9
Erythrocytes 4.82(3.86-5.08) - 4.32
Hemoglobin 137(119-157) - 129
Hematocrit 0.420(0.356-0.470) - 0.380
MCV 88.1(83.0-97.2) - 88.1
MCH 28.5(27.4-33.9) - 29.8
MCHC 323(320-345) - 339
RDW 12.9(9.0-15.0) - 13
Platelet 232 (!) Leukocyte 6.0 DKS - 241

B Neutrophil Granul. 40(44-72)--LOW - 34.6--Low
Lymphocyte 42.7(20-46) - 48--High
Monocytes 5.8(2-12) - 6.5
Eosinophil Granul. 7(0-7) - 7
Basophil Granul. 0.9(0-1) - 0.7
Neutrophil Gran. 3.88 (2.06-6.49) - 3.08
Lymphocyte 3.58 (1.19-3.35)--HIGH - 4.30--High
Monocytes 0.40(0.12-0.84) - 0.57
Eosinophil Gran. 0.45 (0.00-0.43)-HIGH - 0.43
Basophil Gran. 0.06 (0.00-0.06) - 0.06

I've actually had three other blood panels done, and they look almost identical to these ones.
The deviations are always the same. It's really starting to worry me because I just feel like something isn't quite right. Please, if anyone has any insight, advice, or even just a suggestion, I would appreciate it so much. Thanks.

Patrick Moore said:Hi there.. I'm 27 years old, and I've been dealing with hypothyroidism for nearly a year now.. I've been trying to conceive for almost twelve months, but nothing has happened yet.. We've gone through all the standard gynecological exams and everything appears normal.., My husband's side is also perfectly fine..
I've had several blood panels done over the past year.. My doctor maintains that everything is within the normal range.. I even saw an infectious disease specialist—he suggested I just keep monitoring my blood work via regular labs.. However, I can see certain deviations—so if you could take a look..
First blood panel, - - - Second blood panel
Leukocytes 8.3(3.4-9.7) - 8.9
Erythrocytes 4.82(3.86-5.08) - 4.32
Hemoglobin 137(119-157) - 129
Hematocrit 0.420(0.356-0.470) - 0.380
MCV 88.1(83.0-97.2) - 88.1
MCH 28.5(27.4-33.9) - 29.8
MCHC 323(320-345) - 339
RDW 12.9(9.0-15.0) - 13
Platelet 232 (!) Leukocyte 6.0 DKS - 241

BNeutrophil granul. 40(44-72)--LOW - 34.6--Low
Lymphocytes 42.7(20-46) - 48--High
Monocytes 5.8(2-12) - 6.5
Eosinophil granul. 7(0-7) - 7
Basophil granul. 0.9(0-1) - 0.7
Neutrophil gran. 3.88 (2.06-6.49) - 3.08
Lymphocytes 3.58 (1.19-3.35)--HIGH - 4.30--High
Monocytes 0.40(0.12-0.84) - 0.57
Eosinophil gran.0.45 (0.00-0.43)-HIGH - 0.43
Basophil gran. 0.06 (0.00-0.06) - 0.06

Three other blood panels were done too.. and they are very similar to these..
All the deviations are the same.. I am just worried about this >.. I feel like something isn't right... Please, any help or advice.. anything at all.. Thanks

There are some isolated deviations here, but I don't believe any of them are causing the fertility issues.
It has only been a year—keep pushing, stay persistent—I truly believe everything will turn out fine and that you will become a wonderful mother one day.
Good luck! 🙂

Sandra Vaughn50 said:There are some isolated outliers here, but I really don't think any of that is what's causing the trouble with getting pregnant.
It’s only been a year, so please, stay persistent. I truly believe everything is going to work out and you’ll be an amazing mother one day.
Good luck! 🙂

Thanks for getting back to me 😛

Got three different test results here!

1. Cervical swab checking for Enterococcus and E. coli


2. Cervical swab testing for Mycoplasma hominis


3. Urine culture for Enterococcus


Since I have a sensitivity chart for every single bacteria found, I was wondering if Citeral (Ciprofloxacin) is actually the best move here because :

a) based on result #1, the Enterococcus isn't sensitive to it at all

b) and according to the note in result #3, Ciprofloxacin is only meant for uncomplicated infections

I'm a female under 30, and I have a steady partner.
I'm already on my third antibiotic (first Nolicin, now Cephalexin) and honestly, I've been fighting these infections since winter! So, would it be smarter to pick an antibiotic that covers all three findings instead?

Also, how is it even possible that the exact same bacteria (Enterococcus) reacts to Ciprofloxacin in one test (urine culture) but doesn't react to it in the other (cervix)?

Thanks so much in advance for the help! 🙏

swiftheron7 said:I have three lab results

1. Cervical swab for Enterococcus and E. coli


2. Cervical swab for Mycoplasma hominis


3. Urine culture for Enterococcus


Since I have a sensitivity chart for each bacterium showing which antibiotics they respond to, I'm wondering if Citeral (Ciprofloxacin) is the best choice here—especially since :

a) according to result 1, the Enterococcus isn't sensitive to it

b) regarding result 3, the note mentions Ciprofloxacin is only used for uncomplicated infections.

I am under 30, female, and have a steady partner.
I'm currently on my third antibiotic (first Nolicin, now Cephalexin) and I've been battling infections since winter —so, would it be wiser to choose an antibiotic that covers all three findings?

Also, how is it possible that the exact same bacterium (Enterococcus) reacts to Ciprofloxacin in one test (urine culture) but doesn't react to the same antibiotic in another (cervix)?

Thanks in advance for the help. 🙏

Ciprofloxacin is a solid antibiotic choice. In that first test, the Enterococcus wasn't actually tested against Cipro, so it's safe to assume it's sensitive.

We're likely dealing with a standard, highly sensitive strain of Enterococcus—not some resistant strain like VRE (Vancomycin-resistant Enterococcus), which is basically a living nightmare for hospital doctors.

Both Enterococcus samples are probably the same strain; however, even within the same species, you can have different strains... essentially, one person could carry two different types of Enterococcus, two types of Pseudomonas, or two types of Staph... and so on.
It’s the same bacteria, just varying in their level of sensitivity or resistance to antibiotics.

Been dealing with abdominal cramps for about a month and a half now. The intense pains finally died down—thank god—but I’ve still got this constant ache right under my left rib cage that just radiates all over my stomach. Went to see my OBGYN and they found a polyp, some fibroids, and a cyst on my left ovary... though I might get a second opinion from a specialist at Mayo Clinic because I'm not sure about the diagnosis. The cyst is about the size of an almond. Had a CA 125 test done and it came back at 7.4 (< 35.0 kIU/L), so I guess that's good? I've got a follow-up in three months.
How's everyone doing? Any update on those pains? I heard someone had their CABG done.
ESR is sitting at 36—(normal range is 5-28)... I guess.
Lymphocytes 3.8 (1.19 - 3.35) — I guess my Lymphocyte count is a bit high... maybe nothing to worry about, but still—not exactly where it should be.
Alpha-amylase 203 (normal range 23-91)—yeah, that’s definitely high. I guess... maybe just something to watch.
Cholesterol is sitting at 8.2 (normal is 0-5)—not exactly what I was hoping to see... maybe just my luck?
Triglycerides at 2.2... and the target is under 1.7—so yeah, I guess I'm officially off track.
HDL cholesterol is sitting at 1.16—just under that 1.2 mark... I guess.
LDL cholesterol is sitting at 6.04... and that’s way over the limit of 3—not exactly great news, I guess.

Everything else seems to be within the normal range, I guess.

Once Dr. Felix saw the results, she sent me straight to an internist... and then things just went nuts. I mean—more blood work, three different ultrasounds in two days? Total madness.

Amylase is dropping... sedimentation is up, the pain isn't letting up, and I'm just exhausted—completely wiped out.
Just had my third ultrasound—my internist isn't exactly thrilled about what he saw. Apparently, the pancreas looks fine, but there's this oval, echogenic mass sitting right above it (cranially to the tail)—about 2.44x2.78 cm and slightly heterogeneous, though it's the same echogenicity as the pancreas itself. I guess we'll see.
Probably worth getting a CT scan of the pancreas and an MRI—plus a gastroscopy and colonoscopy, and checking CA 19-9 levels. Just my two cents, I guess.
These tests were done up in San Francisco.
So, I ended up getting admitted to the Mayo Clinic for two days.

MRI and CT came back clean—plus gastro, endoscopy, and CA 19-9 are all fine too... no suspicious masses or anything anywhere in the abdomen, I guess.

Out of all the tests they ran—I guess—only these specific values came back high.

GF estimate based on the MDRD formula is 99.5 (>60 ml/min)—I guess that's fine.
GFR estimate based on CKD-EPI formula is 101.7 (> 60 ml/min) — looks okay, I guess.
Basophils at 0.11 (0.00 - 0.06)... I guess that's a bit high—maybe nothing, but still slightly out of range.
Neutrophil granulocytes 7.63 (2.06 - 6.49 10e9/L)—just my luck, I guess.

So, after getting discharged from the hospital, these were the diagnoses they wrote down:

Gastritis, I guess.
Heart failure... I guess.
Diverticulosis... man, what a mess.
Post-appendectomy status... I guess.
Post-cystectomy renal issues... I guess? (2010)
Kidney stones in the left kidney, I guess.
Renal cortical cysts... I guess.
Thyroiditis and Hyperlipoproteinemia
Thyroiditis and Hyperlipoproteinemia—I guess.

I'm 55 years old and I honestly feel... 👎

Of course, I'm still getting hit with those intense pains every now and then—they don't last too long, though... so I guess I'm just hoping that maybe, just maybe, I'll actually last a while.

Thanks in advance for any suggestions, extra digging, or follow-ups.

Sandra Vaughn50 said:Ciprofloxacin is a solid choice for an antibiotic! Always works well for me. In the first lab results, they didn't even test the Enterococcus against Cipro, so I'm just assuming it's sensitive to it!

It’s just a standard, sensitive Enterococcus. Definitely not one of those nasty resistant strains like VRE—now that is a total nightmare for hospital doctors!

Both Enterococcus strains are probably just different versions of the same thing. But honestly, you can have different strains within the exact same species! So, one person could end up with two types of Enterococcus, two types of Pseudomonas, two types of Staph... you name it!
It’s the exact same bacteria! Just different levels of how they react to antibiotics.

Thanks so much for the reply!

It’s honestly so confusing! It feels like neither my GP nor my OBGYN actually knows what they're doing. Both of them were just like, "Oh, alright then, just take this and give it a shot." Such a weird vibe!

There’s just way too much "maybe" floating around here! I was hoping someone might have a more certain answer, but it seems pretty obvious we're dealing with that kind of bacteria where you basically just cycle through different antibiotics until one finally hits the mark and clears the inflammation.

😢

Edit:
I didn't realize that part was bolded! I just assumed if there wasn't an S, it wouldn't react to Ciprofloxacin. Thanks again—honestly, this isn't even such bad news then!

Quote : Felix the Cat

ambernomad36 said:Gastritis—an inflammation of the stomach lining. It’s much like how rust slowly eats away at an old iron gate if left untreated.
Heart failure—an exhausting reality to face.
Diverticulosis—an issue where small pouches develop in the intestinal wall—is much like a structural weakness in an old highway; over time, the pressure can cause the surface to bulge.
Post-appendectomy status.
Post-cystectomy renal insufficiency (2010) — an observation from my own history.
Nephrolithiasis — left side.
Renal cortical cysts—essentially small, fluid-filled sacs on the outer layer of the kidney—often behave like quiet, uninvited guests in a house; they show up without much fanfare and usually just sit there.
Thyroiditis and Hyperlipoproteinemia — a delicate balance to maintain.
Thyroiditis and Hyperlipoproteinemia—an interesting intersection of metabolic challenges.

I am 55 years old—and I truly feel... 👎

Of course, I still experience bouts of intense pain from time to time—though they don't last long... which is why I’m hoping that, at least in my case, I can hold out for a while.

I am truly grateful for any suggestions, further research, or follow-up checks you might offer—every bit helps.

Perhaps that stone in my left kidney is the underlying cause of these symptoms—it’s hard to say for sure.
Amylase levels might rise—which is a tricky one, since it’s such an unspecific enzyme produced by various organs, including the kidneys.
You should check in with a urologist—there is a chance that a Purchase could be broken up using the ESWL method.

Could someone take a look at these hormone levels? I'm in my early 20s. Historically, I've dealt with some issues regarding my right testicle; it's slightly smaller than average and doesn't seem to be fully functional—maybe only about 20-30% capacity. The left one is perfectly fine.

I finally got the full results back.

TSH 4.15 0.465-4.68 mIU/L
Progesterone 0.90 0.0-0.64 nmol/L
Prolactin 218 73-407 mIU/L
Testosterone 16.17 4.56-28.2 nmol/L (some labs go up to 40)
FSH 3.29 0.9-12 mIU/mL
LH 2.92 1.1-8.7 mIU/mL
Estradiol 83 40-162 pmol/L
Morning Cortisol 455.4 101.2-535.7 nmol/L
Afternoon Cortisol 276.1 79-477.8 nmol/L

Naturally, I am feeling the effects through a lower libido than you'd expect for my age, poor concentration, constant fatigue, and a need for more sleep than usual (especially afternoon naps). My overall vitality and energy levels have been low lately, and my muscle mass is also lacking, likely due to the testosterone levels. I've already ruled out thyroid issues, as I had those checked previously.

What are your thoughts on therapy...

Based on everything you've listed, I’d say we're looking at a thyroid issue. Your TSH is sitting right at the upper limit of the normal range. Did you actually get your T3 and T4 levels checked?

Rachel Palmer56 said:Alright, sorry, I just wrote down everything that showed up as high or low..
Basically, this is a follow-up. I have asthma, some stomach issues (ulcers, GERD...), and I'm currently being seen by a rheumatologist with an undefined diagnosis.
For the last year, my white cell count and ESR have been constantly elevated. A few months ago, my white cells were at 21.
ESR (sed rate) was 38 after one hour.

That's why these results actually made me feel a bit better.
White cells are back down to 8.91, like I mentioned before.

ESR is 18.

RBC 3.93

Hemoglobin 138

Hematocrit 0.333

MCV 85.2

MCH 35.2

MCHC 413

RDW 12.7

Platelet 382

MPV 5.9

So, that's the full picture from two weeks ago. Since then, my lymph nodes have swollen up, but I'm hoping things are looking pretty okay. Thanks in advance for any input.🙂

Oh, and I'm still waiting on these other labs; they should be ready in about two weeks: >

Total Protein (*) 72 g/L (Ref: 66 to 81)

C-reactive protein (CRP) (*) 12.1 H mg/L

Rheumatoid factor (RF) (*) < 20.0 - IU/ml (Ref: up to 30)
Sample Complement Result Unit Reference Interval
vS C3 complement component (*) 1.42 g/L (Ref: 0.83 to 1.93)
vS C4 complement component (*) 0.29 g/L (Ref: 0.15 to 0.57)

Sample Serum Protein Electrophoresis Result Unit Reference Interval
vS Albumin (*) 56.0 % (Ref: 55.8 to 66.1)
vS Alpha-1-globulins (*) 4.7 % (Ref: 2.9 to 4.9)
vS Alpha-2-globulins (*) 11.0 % (Ref: 7.1 to 11.8)
vS Beta-globulins (*) 11.3 % (Ref: 8.4 to 13.1)
vS Gamma-globulins (*) 17.0 % (Ref: 11.1 to 18.8)
R Albumin/globulin ratio 1.27 (Ref: 0.8 to 2)
vS Albumin (*) 40.3 g/L (Ref: 40.2 to 47.6)
vS Alpha-1-globulins (*) 3.4 g/L (Ref: 2.1 to 3.5)
vS Alpha-2-globulins (*) 7.9 g/L (Ref: 5.1 to 8.5)
vS Beta-globulins (*) 8.1 g/L (Ref: 6 to 9.4)
vS Gamma-globulins (*) 12.2 g/L (Ref: 8 to 13.5)
Sample Circulating Immune Complexes Result Unit Reference Interval

vS Circulating immune complexes-IgG 165 H mg/L (Ref: up to 130)
vS Circulating immune complexes-IgM 118 H mg/L (Ref: up to 100)

I just got these extra results back. Personally, they don't look too bad to me, but I'd love to get your thoughts again. Just a heads up, all these tests were done at the same time.
Thanks for the help.🙂

Rachel Palmer56 said:Total Proteins, (*) 72 g/L (Range: 66 to 81)

C-reactive protein (CRP) (*) 12.1 H mg/L

vs Rheumatoid factor (RF) (*) < 20.0 - IU/ml (Range: up to 30)
Sample Complement Result Unit Reference Interval
vs C3 complement component (*) 1.42 g/L (Range: 0.83 to 1.93)
vs C4 complement component (*) 0.29 g/L (Range: 0.15 to 0.57)

Sample Serum Protein Electrophoresis Result Unit Reference Interval
vs Albumin (*) 56.0 % (Range: 55.8 to 66.1)
vs Alpha-1-globulins (*) 4.7 % (Range: 2.9 to 4.9)
vs Alpha-2-globulins (*) 11.0 % (Range: 7.1 to 11.8)
vs Beta-globulins (*) 11.3 % (Range: 8.4 to 13.1)
vs Gamma-globulins (*) 17.0 % (Range: 11.1 to 18.8)
R Albumin/globulin ratio 1.27 - (Range: 0.8 to 2)
vs Albumin (*) 40.3 g/L (Range: 40.2 to 47.6)
vs Alpha-1-globulins (*) 3.4 g/L (Range: 2.1 to 3.5)
vs Alpha-2-globulins (*) 7.9 g/L (Range: 5.1 to 8.5)
vs Beta-globulins (*) 8.1 g/L (Range: 6 to 9.4)
vs Gamma-globulins (*) 12.2 g/L (Range: 8 to 13.5)
Sample Circulating Immune Complexes Result Unit Reference Interval

vs Circulating immune complexes-IgG 165 H mg/L (Range: up to 130)
vs Circulating immune complexes-IgM 118 H mg/L (Range: up to 100)

I just received some more results—to me, they don't look too bad personally—but I would like to ask for your opinions once more; all tests were performed at the same time.
Thank you in advance 🙂

It looks fine. 👍
ANA and ENA are still missing.

By the way, are there any other symptoms alongside the swollen lymph nodes (which area are they in?)—such as unexplained fevers, night sweats, weight loss, or skin itching?

Sandra Vaughn50 said:Looks good. 👍
Still need ANA and ENA results.

Anyway, any other symptoms besides those swollen lymph nodes? (Where are they located?) And stuff like unexplained fevers, night sweats, losing weight, or itchy skin?

One of those new nodes is basically right on the surface, and the other one is on the right side of my neck—but that one’s been there for years. It was biopsied once and the result was reactive hyperplasia, if I remember right. My skin is super itchy too, which is crazy because there's no visible reason, skin looks clear. Temperature isn't an issue, nothing major.

Rachel Palmer56 said:One of these newly formed nodes is right on my chin—almost on the edge—and the other one is on the right side of my neck, though that one has been there for years. It was biopsied once before, and if I recall correctly, the result was reactive hyperplasia. I've also had this strange skin itching—which is odd since my skin looks clear—and my temperature is slightly elevated, but nothing major.

Once the immunological workup is finished, it might be wise to consult a hematologist—just to rule out any lymphoproliferative issues.
It’s likely nothing at all—but better safe than sorry.

If you ask me, I would go back for another tissue sample from the enlarged node—and definitely skip the fine-needle aspiration, which is pretty much useless. You really need a "core biopsy," where they use a wider needle to get a proper sample.
Please discuss this option with your primary care physician.