Dealing with Dupuytren's contracture

I’m looking for some advice here.

My wife, who is 44, has already undergone three different surgeries on her right hand—specifically involving the tendons near her pinky—over the last three years.
The diagnosis is as follows:
Status post partial resection of the palmar fascia of the right hand (Dupuytren's contracture)
Status post resection of the fibrosis of the fourth and fifth digits of the right hand

If things continue to deteriorate like this, I’m wondering if there is any actual guidance available beyond just finding a new career path. Her current employer doesn't offer light-duty options, which essentially means she's facing a choice between resigning or being let go.
She currently has a referral to see a rheumatologist regarding non-specific polyarthritis.
She also consulted a private orthopedic specialist who basically told her she’s just having a run of bad luck and needs more surgery before the condition can even be managed.

Greetings from Indianapolis.

Hey there! Since I work in physical therapy, I can tell you from experience that the recurrence rate after surgery is pretty high—honestly, it’s closer to 70%. I know that’s not exactly comforting to hear, but it’s just the reality of the situation. I'm not sure what she does for a living, but repetitive microtraumas—those little nagging movements at work—play a huge role in how this develops. Plus, once someone goes on medical leave or finishes physical therapy after surgery, they usually have to jump right back into work, which is obviously bad for recovery... Surgery really should be the last resort, but I've heard there might be medication options out there, so definitely ask about those (I'm not a doctor, so don't take my word for it). But why am I even telling you all this? You guys have probably become experts after three surgeries anyway 🙂

She was sent to a rheumatologist to see if it's some kind of arthritis (like polyarthritis, where multiple joints get inflamed), which would explain the tissue thickening or fibrosis. They'll run specific tests and likely send her for more follow-ups, probably immunological ones.

My advice: even though private specialists can be pricey... if surgery becomes necessary again, I’d highly recommend finding high-quality kinesitherapy (someone who will actually focus on her and do it right, rather than a "factory" clinic where they just hand you a list of exercises after two days and let you fend for yourself—unfortunately, I work in a hospital setting like that, so I've seen how much damage people can do when they try to be their own therapist)

I won't suggest changing jobs because, let's face it, that's basically science fiction these days.

Hope this helps a little!

I appreciate the advice provided here.

Best regards.