Psychotropic medication discussion thread
Started by Robin Myers91 · · 👁 44 views · 10K replies
#343 ·
fadedbear92 said:Sorry, but they are definitely used for relaxation and managing panic attacks. Of course, if you take it and just lie down to unwind, falling asleep is easy—especially at higher doses.
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Alprazolam
Alprazolam Systematic (IUPAC) name
8-chloro-1-methyl-6-phenyl-4H-
[1,2,4]triazolo[4,3-a][1,4]benzodiazepine
Identifiers
CAS number 28981-97-7
ATC code N05BA12
PubChem 2118
DrugBank APRD00280
ChemSpider 2034
Chemical data
Formula C17H13ClN4
Mol. mass 308.765
Pharmacokinetic data
Bioavailability 80-90%
Metabolism Hepatic, via Cytochrome P450 3 A4 Half
Half life Immediate release: 11.2 hours;[1] Extended release: 10.7-15.8 hours[2]
Excretion Renal
Therapeutic considerations
Pregnancy cat. D(USA)
Legal status Schedule IV(USA)
Routes Oral Alprazolam
Alprazolam, also known under the trade names Xanax and Ativan, is a short-acting drug of the benzodiazepine class used to treat moderate to severe anxiety disorders, panic attacks, and as an adjunctive treatment for anxiety associated with moderate depression. It is also available in an extended release form, Xanax XR. Both forms are now available generically. Alprazolam possesses anxiolytic, sedative, hypnotic, amnesic, anticonvulsant and muscle relaxant properties.[3]
Alprazolam is a potentially addictive drug and long term use of alprazolam may cause a physical dependence to develop and benzodiazepine withdrawal syndrome to appear during discontinuation. In the USA, alprazolam is the most commonly misused benzodiazepine and is a Schedule IV controlled drug.[
I'm speaking from my own experience and what I've seen with patients. Forget what Wikipedia says—the reality is that you can actually function the next morning after taking Xanax. Some other sedatives or things like Sanval don't have the same effect. Patients wake up with dizziness or headaches. Not everyone, but some people handle them poorly. It’s also very easy to get hooked on alprazolam. It creates dependency.
The 2 mg XR doses release slowly and have a longer-lasting effect. 👍
Not everything in Wikipedia is accurate. That stuff is too general. Real-world practice is completely different. We even have a woman on this forum who takes four Sanval and still can't sleep. Everything is individual. Medicine isn't math.👍😉
#344 ·
fadedbear92 said:Prozac has been on the market since 1988.
Prozac was introduced later, around 1995.
Here are the main differences between them:
This is actually a great link—it lays out the differences between things like Prozac and Faverin really clearly. It explains why you might need to pair Faverin with an anxiolytic, whereas with Prozac, you wouldn't necessarily need something like Paxil alongside it.
#345 ·
Scott Harris7 said:Let me correct a misconception here. 😁 Regarding Xanax, everything really boils down to the dosage. A 0.25 mg dose doesn't stay in your system for very long—but then again, there's also the 2mg extended-release version. Those are designed to release slowly, so they stick around much longer.
And it’s simply not true to say that Xanax isn't used for sleep. It is absolutely prescribed for that purpose, and it serves its function.👍
I mean, look—if we're talking about the actual foundation of treating panic attacks, you’ve got things like Xanax, Ativan, or whatever other benzodiazepines they're handing out these days... I guess it really depends on what the doctor thinks is best, though I always feel like there's so much guesswork involved in these prescriptions. 😁 It’ll probably help you drift off, too—since, I mean, that's basically what all benzodiazepines do, isn't it? It's one of their core properties, after all.
So, look—if your primary diagnosis is Panic Disorder, I don't think a specialist is going to just throw Xanax at you alongside something like Normabal. It doesn't really make sense, I guess. If you’re actually struggling with serious sleep issues, they’d probably lean toward something like Sanval instead—since that stuff hits those hypnotic receptors a bit harder, if you know what I mean. 😍
#346 ·
That’s exactly why I emphasized that we shouldn't just shove all these medications into strict little boxes... it really comes down to the diagnosis, the specific symptoms, what they're being used for, and the individual patient. It's not exactly breaking news. Besides, I already pointed out that alprazolams tend to linger in your system for quite a while anyway. Obviously, if you take a massive dose, there's going to be a much higher concentration in your bloodstream, and it'll naturally take longer to clear out. I don't see the point of Scott Harris7's comment...☕As for alprazolams, I was already well aware of how they work and was prescribing them in my clinic while some people were still stuck in their grad school studies.😂
#348 ·
I started on 50 mg of Effexor yesterday, and honestly, I’m just counting down the minutes until it actually kicks in because this anxiety is absolutely draining the life out of me.😢
#349 ·
velvetsailor26 said:I started on 50 mg of Effexor yesterday, and honestly, I’m just counting down the minutes until it actually kicks in because this anxiety is absolutely draining the life out of me.😢
You have to be patient—it’s a process. I guess you could take some xanax or another anxiolytic while you wait for the AD to actually kick in.👍
#350 ·
Correction on a misconception:
The whole point of using extended-release meds is about maintaining steady levels throughout the day. In cases like this, people shouldn't be thinking that slow-release formulas are meant to boost the actual bioavailability (!)—that’s not how it works. It’s really just about avoiding the hassle of constant dosing and having to babysit a strict schedule. If you need 2 mg total per day, it doesn't matter if you take it in three separate hits or just one single depot dose... the goal is simply to ensure there's a consistent concentration in your bloodstream—and by extension, your brain—all day long. There’s a lot more to pharmacology than just listening to some pharmaceutical rep's polished sales pitch...🤷
The whole point of using extended-release meds is about maintaining steady levels throughout the day. In cases like this, people shouldn't be thinking that slow-release formulas are meant to boost the actual bioavailability (!)—that’s not how it works. It’s really just about avoiding the hassle of constant dosing and having to babysit a strict schedule. If you need 2 mg total per day, it doesn't matter if you take it in three separate hits or just one single depot dose... the goal is simply to ensure there's a consistent concentration in your bloodstream—and by extension, your brain—all day long. There’s a lot more to pharmacology than just listening to some pharmaceutical rep's polished sales pitch...🤷
#351 ·
cosmictinker21 said:Lexapro (escitalopram) is a selective serotonin reuptake inhibitor. Basically, it stops serotonin from being sucked back into the previous neuron, leaving more available for the next cell to actually use. It’s typically prescribed for long-term management of anxiety and depression, or paired with other meds to help with panic attacks, phobias, acute stress, mild PTSD, and as a supplemental treatment for various acute or chronic mental health conditions. You do have to be patient with it, though; you have to wait for enough serotonin to build up in the system. Most people start on low doses for about 7 to 10 days, and you have to taper off slowly once symptoms subside. Not because it’s addictive, mind you, but because stopping abruptly can cause a sudden drop in serotonin levels—which leads to consequences... essentially, you just fall right back into bed. Despite what some newer studies suggest, with Lexapro you really should give it time rather than jumping to a different medication after just a week... Side effects tend to be milder and less frequent compared to other drugs. We're usually talking things like constipation, a slight headache, bloating, drowsiness, muscle or mental fatigue, and a bit of emotional blunting. That doesn't mean you stop feeling things entirely; it just means you're navigating situations with a bit more realism. In a way, your brain isn't getting exhausted by the constant fears, anxieties, or those massive emotional storms that end up paralyzing your ability to function and live a normal life. If the therapy is dialed in correctly, you'll definitely see whether it's working after a few months, depending on whether you're dealing with a chronic issue or if life just hit you hard with some temporary stress. Don't let fear get the better of you; nothing catastrophic is going to happen, and nobody is going to poison themselves on these types of medications. I mean, even when you take Advil, you might end up with heartburn or an upset stomach, right? These are all thoroughly tested doses, nowhere near toxic levels. It's true that everyone's neural structure is unique—just like how no two noses, hands, or eyes are identical—so one person might need more while another needs less; some won't feel a thing, while others react quite sensitively. This is especially true with psychotropic drugs, so you have to be meticulous about choosing and titrating the dosage until you find that sweet spot.👍
That part I bolded—this obvious emotional detachment you're talking about—was honestly the absolute best thing for me when I was on Lexapro. 👍 I was just so incredibly chill and centered! 😁
Man, if only I had been born with that kind of "emotional distance" built right in!!! 😍
cosmictinker21 said:Honestly, don't get too hung up on those rigid medical categories—you know, the whole sedative vs. hypnotic vs. antidepressant vs. antipsychotic vs. mood stabilizer vs. anxiolytic thing. Most of those classifications are just based on chemical structures, basic biochemical pathways, or whatever specific diagnosis or symptom they’re supposed to target... it's all a bit arbitrary anyway. Take an anxiolytic like Oxazepam, for example; depending on how someone’s body processes and clears it, it might knock one person straight out for a nap, while it might just take the edge off for someone else so they stop crying. Someone else might end up feeling totally lobotomized or just dizzy, and for some people, it won't do anything at all. With benzodiazepines like Valium or Ativan, the deal is that if you take them as a pill, they might induce sleep more slowly, but they're better at relaxing your muscles—plus, you'll feel sluggish and hungover for longer because they linger in your bloodstream. Then there's Alprazolam (Xanax); it doesn't mess with your physical motor skills as much, but it hits the psychomotor side harder. It isn't really meant for sleep, but it's great for preempting anxiety attacks. Since it stays in your system longer, you don't necessarily need to take it strictly every single day. If you've been on standard daily doses, though, you have to taper off very carefully. If you're just taking it occasionally, it's no big deal. It isn't the kind of physical dependency you see with something like Methadone, even though both are heavily regulated psychotropic substances under the law. Personally, if I took something like Valium or Xanax, I think I'd end up stumbling around like a drunk in a ditch...🤷
Well then, what on earth do you take when everything just hits the fan?
#352 ·
Robert Reyes34 said:That part I bolded—this obvious emotional detachment you're talking about—was honestly the absolute best thing for me when I was on Lexapro. 👍 I was just so incredibly chill and centered! 😁
Man, if only I had been born with that kind of "emotional distance" built right in!!! 😍
Well then, what on earth do you take when everything just hits the fan?
I found my experience quite similar when I was on Lexapro for a while, though the side effects were simply too intense for me to bear; my jaw would lock up constantly, among other things.
#353 ·
Nicole Barrett76 said:I found my experience quite similar when I was on Lexapro for a while, though the side effects were simply too intense for me to bear; my jaw would lock up constantly, among other things.
You could have tried a much lower dose back then, maybe not even hitting 10 mg. That jaw tension thing is pretty common with Lexapro, though quite annoying. If it’s really bothering you, you might want to look into something else, like Faverin or Paxil.
As for what I take? Honestly, I don't take anything because I don't actually need it. When I was dealing with dizziness, headaches, passing out, and total exhaustion, the first thing my neurologist jumped to was that I was depressed or anxious—post-divorce depression, right? As if. Five years after my divorce, give me a break...🤣 So, being the "good patient" I am, I went to the psychiatrist. Did all the personality tests, the IQ stuff, blah blah blah, and he tells me we'll start with Lexapro until we figure out what's actually going on. Okay. But deep down, I didn't feel like his typical patient, so I went to see his colleague. Just followed orders, right? This second guy looks at me like I'm some clueless kid, talks to me for hours, and still has no clue how to handle my case. Eventually, he suggested I see a specialist who handles the weird cases, since he couldn't find any specific pathology or psychiatric symptoms. So I saw the third one, and we basically ended up just grabbing coffee because there wasn't much else to talk about. I figured I should probably see an internist too and get a proper neurological workup done. Meanwhile, I was dutifully popping those white pills, feeling worse and worse, sleeping 12 hours a day like a newborn, totally out of it... felt like I was halfway through a six-pack of beer every single day. It was a nightmare, truly... And that went on for months. Whether it was depression, schizophrenia, paranoia, whatever—I just wanted to feel better. Until the lab results finally came back. Turns out my thyroid is sluggish, barely doing its job, though not quite ready for medication yet. Then my other hormones started acting up, and since I'm dealing with circulation issues like most people my age, I had some issues with blood flow to the head, haha. They actually thought it might be Alzheimer's. Or before that, a brain tumor! You can imagine how "cheerful" I was with those ideas... a tumor and Alzheimer's, and they're prescribing me Lexapro and calling it acute post-divorce depression!😂 It wasn't until I went back to the neurologist with reports from three different psychiatrists, a psychologist, and all my internal medicine labs—MRI, CT, SPECT, the whole nine yards (they practically drained me of three buckets of blood just to keep me from collapsing)😠—that I told him thanks for everything. Thanks for making me listen to you instead of listening to myself, my body, or my own intuition (you can't really argue with someone who supposedly knows more than you)... and said I was done with it all. Now, I feel fine. Just dealing with some joint pain, haha.🤷🤷 ☕
#354 ·
Now, don't go taking this as some kind of universal law, because it isn't! Typically, a doctor is going to start with the most straightforward, common diagnosis first—it’s just how the process works until they pinpoint exactly what’s going on. You really have to be patient here. It's not worth jumping from one specialist to another like you're swapping out old socks just because you didn't like the vibe of one consultation... If something feels off, or if your doctor suggests more testing, or if you're genuinely struggling with symptoms and just can't find any peace of mind, then by all means, push for those tests. You need to be certain you're okay. Get the scans, run the labs, do whatever is necessary to rule out any underlying physical issues with absolute certainty. Once you've cleared the organic stuff from the table, that's when you should really lean into whatever advice your therapist is giving you.☕
#355 ·
cosmictinker21 said:Correction on a misconception:
The whole point of using extended-release meds is about maintaining steady levels throughout the day. In cases like this, people shouldn't be thinking that slow-release formulas are meant to boost the actual bioavailability (!)—that’s not how it works. It’s really just about avoiding the hassle of constant dosing and having to babysit a strict schedule. If you need 2 mg total per day, it doesn't matter if you take it in three separate hits or just one single depot dose... the goal is simply to ensure there's a consistent concentration in your bloodstream—and by extension, your brain—all day long. There’s a lot more to pharmacology than just listening to some pharmaceutical rep's polished sales pitch...🤷
A 2 mg SR dose means it's being released gradually. There is a massive difference between what you read in a textbook and how clinical medicine actually works when treating real patients.
Regardless, taking 3x 0.5 mg or 3x 0.25 mg is absolutely not the same thing as taking a 2 mg dose.
Maybe try brushing up on sixth-grade math and calculate which dose is actually larger.
It isn't rocket science. I hope that finally sinks in.🙄😁😛
#356 ·
cosmictinker21 said:You could have tried a much lower dose back then, maybe not even hitting 10 mg. That jaw tension thing is pretty common with Lexapro, though quite annoying. If it’s really bothering you, you might want to look into something else, like Faverin or Paxil.
As for what I take? Honestly, I don't take anything because I don't actually need it. When I was dealing with dizziness, headaches, passing out, and total exhaustion, the first thing my neurologist jumped to was that I was depressed or anxious—post-divorce depression, right? As if. Five years after my divorce, give me a break...🤣 So, being the "good patient" I am, I went to the psychiatrist. Did all the personality tests, the IQ stuff, blah blah blah, and he tells me we'll start with Lexapro until we figure out what's actually going on. Okay. But deep down, I didn't feel like his typical patient, so I went to see his colleague. Just followed orders, right? This second guy looks at me like I'm some clueless kid, talks to me for hours, and still has no clue how to handle my case. Eventually, he suggested I see a specialist who handles the weird cases, since he couldn't find any specific pathology or psychiatric symptoms. So I saw the third one, and we basically ended up just grabbing coffee because there wasn't much else to talk about. I figured I should probably see an internist too and get a proper neurological workup done. Meanwhile, I was dutifully popping those white pills, feeling worse and worse, sleeping 12 hours a day like a newborn, totally out of it... felt like I was halfway through a six-pack of beer every single day. It was a nightmare, truly... And that went on for months. Whether it was depression, schizophrenia, paranoia, whatever—I just wanted to feel better. Until the lab results finally came back. Turns out my thyroid is sluggish, barely doing its job, though not quite ready for medication yet. Then my other hormones started acting up, and since I'm dealing with circulation issues like most people my age, I had some issues with blood flow to the head, haha. They actually thought it might be Alzheimer's. Or before that, a brain tumor! You can imagine how "cheerful" I was with those ideas... a tumor and Alzheimer's, and they're prescribing me Lexapro and calling it acute post-divorce depression!😂 It wasn't until I went back to the neurologist with reports from three different psychiatrists, a psychologist, and all my internal medicine labs—MRI, CT, SPECT, the whole nine yards (they practically drained me of three buckets of blood just to keep me from collapsing)😠—that I told him thanks for everything. Thanks for making me listen to you instead of listening to myself, my body, or my own intuition (you can't really argue with someone who supposedly knows more than you)... and said I was done with it all. Now, I feel fine. Just dealing with some joint pain, haha.🤷🤷 ☕
Are you saying that you felt an immediate sense of relief once you accepted the possibility of simply living your life without that relentless cycle of testing and searching...? I don't think I quite follow your logic, but essentially, you're saying there was nothing physically wrong, nor anything psychologically amiss, but rather...🤷 just *that*?!
I suppose most of us eventually find ourselves drifting toward that same sort of plateau, where we're just stuck in limbo, neither moving forward nor backward.
Yes, you truly do have to learn how to listen to oneself, just as you said.
#357 ·
Oh, Zulejka, Scott Harris7, Hector, Jerry Collins... at this rate, we might as well start expecting Hannibal, Attila, Alexander the Great, Genghis Khan, Napoleon, or maybe even Stalin, Rommel, or Bush. Ha, ha.😂😂😂
#358 ·
Look, if your total daily dose is 2 mg, it doesn't really matter how you split it up when you're using a depot formulation. Do a little math instead of just complaining. Besides, this isn't some abstract theory; it’s just what happens when you actually get your hands dirty doing the work. Jerry Collins, Jerry Collins... you're basically Achilles, except you're going down because of a tiny little flaw in your heel...🤣🤷☕
#359 ·
It looks like you might need to brush up on your basic multiplication tables. There is a massive difference between taking a single 2 mg dose once a day and splitting it up into three doses of 0.5 mg or three doses of 0.25 mg.
In every scenario you mentioned, those individual amounts are significantly lower than a single 2 mg pill.
Do yourself a favor and grab a calculator to run the math if the arithmetic is proving to be a struggle. 😂🤣
In every scenario you mentioned, those individual amounts are significantly lower than a single 2 mg pill.
Do yourself a favor and grab a calculator to run the math if the arithmetic is proving to be a struggle. 😂🤣
#360 ·
It truly appears that the complexities of romantic relationships are what actually keep this spinning globe turning. 🤔
Honestly, looking at this forum, one might think we were hosting an endless assembly of legendary generals, world-conquering emperors, or perhaps even those mythic Greek heroes from the old epics!
Everyone here acts like a singular, unstoppable hero, yet when you step outside into the real world—you know, the actual life we lead away from these screens—that heroic energy seems to vanish entirely into thin air. 😉
Honestly, looking at this forum, one might think we were hosting an endless assembly of legendary generals, world-conquering emperors, or perhaps even those mythic Greek heroes from the old epics!
Everyone here acts like a singular, unstoppable hero, yet when you step outside into the real world—you know, the actual life we lead away from these screens—that heroic energy seems to vanish entirely into thin air. 😉
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