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Lab results - looking for opinions [PLEASE READ 1ST POST]

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Participants vividsailor7redcrane22Sandra Rivera37swiftbear86melloworca6Dana Martin87ironskipper80mellowgardener15goldenmarlin6analogbison13Nicholas Myersstormygardener34Roger RodriguezDonna Mitchell3Kenneth Vaughn2Laura Ward98briskseal32Susan Vaughn46Zachary Lewis4driftingmason52rustyheron55Laura Chavez47vividstag24lonecanyon8 …
Nicholas Myers Nicholas Myers Active Member
163 messages
joined Jan 2012
#2221 ·
briskcrane8 said:What should be done about low erythrocyte, hemoglobin, and hematocrit levels, and what is causing this? I am already in quite a panic and worried, especially since the changes are happening daily and aren't just minimal or negligible.

Hello,

A lot of data and parameters are missing before we can say anything meaningful, but based on what you’ve shared, this anemia looks more like what we call anemia of chronic disease. Supporting this are the low iron concentration, low transferrin saturation (though it's still slightly above 15%), and low TIBC, while ferritin stays within the normal range. Of course, it could also be a mixed anemia—meaning several different factors are contributing to the drop.

If we are looking at anemia of chronic disease, bleeding wouldn't be the culprit here; instead, it would be something else entirely: chronic inflammation, malignancy, or an autoimmune issue.

You didn't mention, for instance, your sedimentation rate or CRP, which would serve as potential indicators for this type of anemia.

We are also missing one fundamental piece of the puzzle: the MCV.

Furthermore, you keep citing lymphocyte percentages, but there is no mention of the absolute leukocyte count. Without that, those percentage shifts can't even be interpreted.

In any case, this anemia is a signal that something is happening. To figure out exactly what, a broader diagnostic workup is clearly necessary. A primary care physician is mistaken if they think this can be handled with a single referral to the ER; the ER isn't the place for this kind of investigation.

The lady needs to see a hematologist first, and then we can see what the next steps should be.
swiftgull37 said:I'm a girl, and my androstendion hormone is high androstendion - 13.8 (CLIA method. Ref interval 0.7-12.9.

Note and comment: D5

Please, until I see my doctor, the annual results are... what is going on?

Elevated androstendion levels can be linked to PCOS (Polycystic Ovary Syndrome). One possible explanation for this might be insulin resistance—essentially, elevated insulin levels stimulating androgen production in the ovaries.

Androstendion itself can also be adrenal in origin, stemming from the adrenal glands due to various different disorders.

It is impossible to determine exactly what is happening based solely on these numbers.
Nicholas Myers Nicholas Myers Active Member
163 messages
joined Jan 2012
#2222 ·
Gerald Nelson3 said:Hi,
my wife had blood drawn from her finger at a private doctor's office, and this is what it says:
Biochemical analysis:

P-AMYL= 14.0
HG= 6.75

Now, I assume the first one is amylase, but I have no clue what the second one, HG, is. Basically, the doctor told her her immune system was weak and gave her a B vitamin injection.
It feels totally unrelated to me—please let me know what you think!

One really needs to see the full set of labs. Claiming someone has a weakened immune system and treating it with B vitamins, as you described, doesn't follow any logical path. It sounds like a few routine tests were run showing nothing out of the ordinary, so the patient's issues were simply brushed off as "stress and low immunity." Giving B vitamins was likely just an attempt to provide *something*, though the clinical purpose is questionable.
bluebison2 said:Hello, I received my tissue typing results and would appreciate some insight.🙂
HLA-A 0203
HLA-B 08ND
HLA-DRB1* 0311

For the past year, I've been dealing with joint pain, most intense in my hands. For the last two months, there's been noticeable swelling in one finger. I've also had bouts of severe pain in my shoulder and hip. Rheumatoid factor is elevated (53) and Anti-CCP is 721.
No official diagnosis yet, but rheumatoid arthritis is suspected.
I'm 28.

Thanks in advance!

The HLA typing doesn't show a genetic predisposition for rheumatoid arthritis, though that doesn't rule the disease out entirely. When looking at rheumatic conditions, however, there is a predisposition for systemic lupus erythematosus—two of your HLA markers could be linked to that, specifically HLA-DRB1*03 and HLA-B8.

The results also indicate predispositions for other conditions, but nothing else rheumatic.

Chloe Garcia10 said:At the Breyer Clinic, they ran a Troponin I test. The reference interval is div>

That means the result is normal.
Casey Doyle3 Casey Doyle3 Newcomer
6 messages
joined Mar 2016
#2223 ·
Hello,
I have a question for Felix the Cat.
During my last blood draw four months ago, my erythrocyte count was high at 5.85 (the limit is 5.72). Everything else was within the normal range, except for my MCV, which was slightly low at 81.7 (lower limit is 83). My doctor muttered something about how it would be wise to repeat the CBC in three weeks to monitor the hematocrit or hemoglobin levels (on that specific test, hematocrit was 0.478 and hemoglobin was 172). After those three weeks, the results came back:
erythrocytes 5.93—so it rose further—hematocrit 0.488, hemoglobin 173, and that MCV moved up to 82.3, though still just below the limit. I also have a reticulocyte count reading:
42, where the limits are 22-97.
After seeing this, she simply told me I'm just "polycythemic" (full-blooded) and sent me home. I didn't pay much attention to it at first, but being curious, I did some digging online and realized this could potentially be a form of erythrocytosis or polycythemia vera. This is especially concerning since I deal with frequent headaches, though I've had those since I was 15 and they've always been attributed to a misaligned cervical spine. Ultimately, what prompted me to write this post is an itching sensation after showering that has persisted for a few months. Lately, the itching has even started occurring regardless of showering; it isn't intense and passes quickly, but it is generalized. (I should mention that for the last six years, I've dealt with seborrheic dermatitis on my scalp and occasionally some patches on my face.)

From what I can gather, all of this points toward polycythemia. Since my doctor didn't schedule any follow-ups after the last repeat test, should I perhaps take the initiative and request another CBC?
I am 26 years old, 190 cm, and 103 kg. Generally, I feel fine. I have days where I feel tired, but that's likely because I perform heavy physical labor for 8 to 10 hours a day. I haven't noticed any issues with breathing or weakness during work. Also, my iron is practically at the upper limit at 26, and iron binding is all within normal ranges.
Is it possible to have polycythemia or erythrocytosis if both hematocrit and hemoglobin remain within the normal limits on both tests?
I look forward to your thoughts, and I apologize for the long post and the sudden influx of information.
Thank you.
Nicholas Myers Nicholas Myers Active Member
163 messages
joined Jan 2012
#2224 ·
Hello,

I recall your inquiry from a few pages back. At that time, your family doctor suspected possible anemia due to those slightly lower MCV levels and started running tests in that direction.

Normally, I wouldn't dwell on hemoglobin and hematocrit numbers, but since you mentioned aquagenic pruritus and headaches—which, granted, could stem from other issues—these results demand a different perspective.

If you aren't hypoxic (which can be verified via oxygen saturation levels or blood gas analysis), then a hemoglobin level exceeding 165 g/L in a male (or even above 170 g/L depending on the source), combined with a hematocrit of 0.49 or higher alongside symptoms like aquagenic pruritus, is enough to raise suspicion of polycythemia vera.

I suggest seeing a hematologist to rule this out.
Casey Doyle3 Casey Doyle3 Newcomer
6 messages
joined Mar 2016
#2225 ·
Maria Fisher46 said:Dear sir,

I remember seeing your inquiry a few pages back. At that time, your family doctor suspected potential anemia due to those slightly lower MCV values and started running tests in that direction.

Normally, I wouldn't dwell on hemoglobin and hematocrit levels, but since you mentioned aquagenic pruritus and headaches—which, granted, could stem from other issues—these results need to be viewed through a different lens.

If you aren't hypoxic (which can be verified by checking oxygen saturation or blood gas levels), a hemoglobin level above 165 g/L in a man (or even above 170 g/L according to some sources), combined with a hematocrit equal to or greater than 0.49 and the presence of symptoms like aquagenic pruritus, is enough to raise suspicion of Polycythemia Vera.

I suggest seeing a hematologist to rule this out.

Thanks for the quick reply. I have a few more questions if you don't mind clarifying things for me. About five years ago, I saw a neurologist because of these headaches, and the conclusion was that they were caused by a curvature in my cervical spine. Back then, all my blood work was normal, yet the headaches were still there. Is it possible that this is what they call relative polycythemia, or "stress" polycythemia? My leukocyte count is 5 and platelets are 205... shouldn't those also be elevated in cases of Polycythemia Vera?
Could these results be explained by a lack of blood plasma? If that were the case, would I still experience itching and headaches? From what I've read, this seems like a rare condition that mostly affects older people. I'm quite confused by the differences between primary, secondary, and relative polycythemia.
If you could explain that a bit more, I will definitely consult with my doctor.
Nicholas Myers Nicholas Myers Active Member
163 messages
joined Jan 2012
#2226 ·
Casey Doyle3 said:Thanks for the quick reply. I have a few more questions if you don't mind clarifying things for me. Five years ago, I went to a neurologist because of headaches, and the conclusion was an issue with my cervical spine being misaligned. Back then, all my blood work was normal, yet the headaches persisted. Is it possible we're looking at "relative" polycythemia—or "stress-induced" as I read it? My leukocyte count is 5 and platelets are 205... shouldn't the red blood cell count be elevated too if that were the case?
Could these results indicate a plasma deficiency, or would that not cause itching and headaches? From what I can gather, this is a rare condition usually affecting older people. All these classifications—primary, secondary, relative—have me pretty confused.
If you could walk me through this a bit more, I’ll definitely be consulting my doctor regardless.

Suspicion is certainly possible, though the probability of the disease itself remains, as you noted, low.

Neither a leukocyte count of 5,000 per microliter (5x10^9/L) nor a platelet count of 205,000 per microliter rules out the condition.

To give you some perspective, a study involving roughly 1,500 patients with confirmed diagnoses showed the following: leukocyte counts ranged from 3,000 (3x10^9/L) up to 172,000 per microliter, while platelet counts spanned from 70 to 2,370,000 per microliter. While the majority of patients sat around 10,000 leukocytes and 466,000 platelets, there were plenty of outliers on both ends of the spectrum.

Furthermore, to rule out secondary causes, additional testing is required. You simply can't determine that based on a standard complete blood count alone.
Casey Doyle3 Casey Doyle3 Newcomer
6 messages
joined Mar 2016
#2227 ·
Maria Fisher46 said:There is definitely some suspicion here, though the probability of actual disease is low, just as you mentioned.

Neither a leukocyte count of 5,000 per microliter (or 5x10*9/L) nor a platelet count of 205x10*9/L (or 205,000 per microliter) rules out the condition entirely.

To give some context, a study involving roughly 1,500 patients with confirmed diagnoses found the following: leukocyte counts ranged from 3,000 (3x10*9/L) all the way up to 172,000/microliter, while platelet counts spanned from 70 to 2,370,000/microliter. While it’s true that the majority of patients sat around 10,000 leukocytes and 466,000 platelets, there were plenty of outliers on both ends of the spectrum.

Furthermore, you can't rule out secondary causes based on a blood count alone; you'll need more extensive testing to get the full picture.

Thank you so much. So, this isn't just relative—or false—polycythemia; something is definitely off. My doctor simply concluded that I have "plenty of blood" and sent me home.
Nicholas Myers Nicholas Myers Active Member
163 messages
joined Jan 2012
#2228 ·
Casey Doyle3 said:...something definitely isn't right. My doctor just casually concluded I have polycythemia and sent me on my way.

You can't be certain that something is wrong. For all we know, everything might be fine and her assessment could be spot on—but we won't know for sure until we eliminate every doubt.

Good luck. 👍
Bradley Anderson52 Bradley Anderson52 Newcomer
2 messages
joined Aug 2016
#2229 ·
Hello everyone. I recently went in for some routine blood work and just received these results back. Everything looks alright to you? Thanks. Lp

http://www85.zippyshare.com/v/pwKlIUhJ/file.html
Thomas Wells5 Thomas Wells5 Member
38 messages
joined Aug 2017
#2230 ·
Hello there.
I was wondering if Nicholas Myers could help me make sense of these lab results? Because of work, I won't be able to see my own doctor for another two days.
To give some context on why I went in for bloodwork—I’ve been feeling incredibly listless lately. Let’s just call it a lack of willpower; it isn't quite exhaustion, more like a total loss of drive. Most importantly, whenever I get hungry, I feel terrible. I get hit with this sudden weakness and start shaking, but after just a few bites of anything, I feel better almost immediately.
Here are the results:
K. erythrocyte 5.50
K Hgb 165
MCV 91
MCH 30.1
MCHC 330
K. platelets 205
K. leukocyte 10.1 3.4-9.7 they seem a little high for me
non-segmented granulocytes 0
segmented granulocytes 64
lymphocyte 12.3
monocyte 3
basophil 0

TSH Thyroid stimulating hormone 1.467
iron 17.6
UIBC 32.6
TIBC 50.2
urea 4.7
creatinine 83 bilirubin total 14
AST 18
ALT 21
GGT 23
cholesterol 4.5
HDL cholesterol 1.12
LDL cholesterol 2.99
triglycerides 0.85
S-glucose 8.1 and it's running a bit high
U specific gravity 1.024
U pH 6.0
U protein 0
U ketones 0
U bilirubin 0
U urobilinogen normal
U nitrites negative
U erythrocyte/hemoglobin 0
U leukocyte esterase 0
Microscopic examination of urine sediment
U leukocytes 0-2
U mucus a little

Just a side note, I'm no expert, so I don't know if there's a connection between this high glucose reading and the standard finger-prick test the doctor does. When I was at the clinic the day before, my fasting sugar was 5.2.
I'm assuming the difference might be because I had literally two or three bites of some plain bread about two hours before the blood draw.
Nicholas Myers Nicholas Myers Active Member
163 messages
joined Jan 2012
#2231 ·
Bradley Anderson52 said:Hi everyone. Just had some blood work done and got these results back. Is everything looking okay? Thanks. Lp

http://www85.zippyshare.com/v/pwKlIUhJ/file.html

The report looks clean.

Thomas Wells5 said:Best regards
I was hoping Nicholas Myers could help me make sense of these lab results. Because of my job, I won't be able to see my own doctor for another two days.
For context on why I went in—I've been feeling pretty listless lately. Not just tired, but lacking any drive. Most importantly, whenever I get hungry, I feel terrible. I get weak, I start shaking, but after a few bites of anything, I feel better almost immediately.

A slightly elevated total leukocyte count paired with a normal differential doesn't look concerning to me. It would be wise to repeat the test in a week or so to track the trend.

Regarding the symptoms you mentioned (anxiety, tremors, hunger)—they mirror what we call autonomic or neurogenic symptoms of hypoglycemia (low blood sugar). However, the real question is whether hypoglycemia is actually occurring at the exact moment those symptoms strike.

Unfortunately, this glucose reading isn't valid for fasting levels since you had a bite of bread within two hours of the draw. The data isn't reliable for that purpose.

It would be best to coordinate with your doctor to check your plasma glucose concentration right when the symptoms manifest. If the level is above 3.9 mmol/l, then these symptoms aren't tied to hypoglycemia, and you'll need to investigate other causes.

As far as I can tell, the rest of the results are normal.
Susan Lewis2 Susan Lewis2 Member
23 messages
joined Oct 2009
#2232 ·
Gerald Nelson3 said:Hello,
my wife had some blood drawn from her finger at a private doctor's office, and this is what the results show:
Biochemical analysis:

P-AMYL= 14.0
HG= 6.75

I assume the first one refers to amylase, but I have no idea what the second one, HG, represents. Generally speaking, the doctor told her that her immune system seems a bit weak and gave her a Vitamin B injection.
I suspect there might not be much of a connection here, but I would appreciate your thoughts!

Could you tell me where she had the finger prick done? I've been looking for such an option for quite a while now, since I have significant difficulty with standard blood draws.
Mark Anderson90 Mark Anderson90 Member
13 messages
joined Jan 2016
#2233 ·
Nicholas Myers, could you break this down for me too? I'm trying to make sense of everything regarding the myasthenia.

So, looking at these results, some of this stuff is totally outside the normal range:

Erc -5.77 (p)
MCV -82 (s)
MCHC - 354 (p)
Basophils - 0.10 (p)

Urinalysis results came back and looks like erythrocytes are around 10—just sitting right on the borderline (p).
urine sediment:
Erc 3-5
I can't quite make out what you mean by "leu 1-3"—looks like a typo or maybe some shorthand? If you're trying to share lab results or asking about something specific, just drop the details! I'm all ears.

S-glucose - 445 (p)

K -Rtc - 27 (p)

UIBC is sitting at 54.3 (p).

plinovi:
HCO3 23.6 (p)
BE - 1.1 (s)
BE ecf - 0.9 (s)
po2 - 113 (p)
O2 sat is sitting at 98—right on the edge of the normal range.

Just looking at the rest of the lab results, there's a few things worth noting:
My Hgb stays pretty steady around 170—usually hovering between 168 and 173.
Erythropoietin 10 (4-33)
So, what kind of mutation are we talking about here—negative? Does that mean we can 100% rule out primary polycythemia?

Just got some ultrasound results back... they're saying my spleen is looking a bit chunky, measuring in at 12.5. Also, apparently there's some pleural effusion going on. Not exactly the news you want to hear, right?
So, last year they were seeing about 3cm of free fluid in my abdomen, but on this most recent ultrasound, it’s totally gone. No sign of it at all!

Sometimes I get these headaches, and my neck feels like it’s on fire.
Sometimes my hands just get these random tingles, you know? Like a weird buzzing feeling every now and then. Anyone else dealing with that?
Most of the time, I just feel kind of... out of it? Not like I'm actually dizzy or anything, but more like my balance is totally off and my reflexes aren't what they used to be. Just feeling super uncoordinated lately.
Man, I’ve got this weird pressure building up in my ears whenever I yawn... like they just start popping and clicking inside. It’s super strange because they feel totally dry, and there's almost zero wax in there.
Man, I've been running some low-grade fevers too, hitting around 99.5.
Oh, and I should probably mention—I’ve been dealing with some pretty wild blood pressure issues and tachycardia too. My pressure would spike all the way up to like 150/100 or even hitting 200/130, and my heart rate was racing up to 130 bpm. Just a total rollercoaster!
So, for the last six months or so, my blood pressure has been pretty much sitting right around 120/80. It’s super steady like that. Every once in a blue moon, it might jump up to 140/80, but honestly, most of the time it just cruises between 110/75 and 130/80. Pretty chill, right?
Man, I've had this happen a couple of times lately where I just feel like I can't catch my breath. It’s been happening while I’m sleeping too, which is honestly pretty wild.
Basically, I've been out of the game for about a year now. Honestly, I'm just waiting for things to finally turn around, but nothing significant has really kicked in yet. Still hanging in there, though!

One more thing—could some kind of viral infection be behind all these symptoms and this blood work?
So, for about a year now, I've been dealing with this reddish discharge that looks almost like little polyps, plus my tonsils are a bit swollen and keep spitting out that white gunk. Here’s the lab report from the clinic:
OTS - just a shorter reflex.
RNS - deviation to the right
OFS - tonsils are outside the arches and looking pretty asymmetrical.
ASTO hit a solid 59!

Man, I was grinding away at that EBV stuff for like half a year straight.
So, just got some news back... EBV VCA IgG came back positive at 750. Still processing everything!
Man, my IgG is sitting at 132... that's wild.

Still got that annoying runny nose hanging on, but hey, it should finally be cleared up by the end of the day!

Just so you guys know, I don't drink, I don't smoke, and my diet is totally on point—zero junk food over here.
Height, weight—186 cm, 83 kg, and I'm 22.
I've been healthy my entire life, seriously—never had a single issue. Honestly, I was always in peak condition too: constantly out cycling, swimming, running... just staying super active.

And just when I thought I was done, my nasal swab results finally showed up:

So, I just got the results back from the nasal swab, and here’s the breakdown: they found some cylindrical ciliated and secretory cells that look pretty inflamed and a bit worn down. On top of that, there are neutrophil granulocytes, some cellular debris, and bacteria hanging out in there too.
No eosinophil granulocytes found.
Thomas Wells5 Thomas Wells5 Member
38 messages
joined Aug 2017
#2234 ·
Maria Fisher46 said:A slightly elevated total leukocyte count with a normal differential blood count doesn't look particularly concerning to me. It would be wise to repeat the test in a week or two just to track how that number trends.

Furthermore, regarding the symptoms you mentioned (anxiety, tremors, hunger), they sound quite similar to the autonomic or neurogenic symptoms associated with hypoglycemia (low blood sugar). However, the real question is whether hypoglycemia was actually occurring at the exact moment those symptoms hit.

Unfortunately, this specific blood glucose reading isn't reliable because you had a bite of bread within two hours of the draw; therefore, the result doesn't truly reflect a fasting state.

It would be ideal if you could coordinate with your doctor to measure your plasma glucose levels right when the symptoms occur. If the level is above 3.9 mmol/l at that time, then those symptoms aren't tied to hypoglycemia, and you'll need to look elsewhere for the cause.

As for the rest of the results, everything looks normal to me.

We checked my sugar at the doctor's office again—though I wasn't strictly fasting—and it came back at 6.2. They ran an EKG and everything looked fine there, too. The doc concluded that I’m just stressing myself out way too much (which is fueling my chronic gastritis and GERD), so he prescribed Misar 0.25 and told me to check back in with him in about 10 days.
Jesse Williams14 Jesse Williams14 Newcomer
7 messages
joined Feb 2016
#2235 ·
Hey, Felix the Cat, if you could help me make sense of this blood work... maybe give a quick breakdown of what we're looking at here.

It’s for a patient (54F) dealing with liver cirrhosis—alcoholism has been ruled out.
She needs a transplant, but our main goal right now is pinning down the actual cause of the cirrhosis. The doctor suspected elevated copper or iron levels. Turns out, copper is totally fine, but the ferritin is through the roof.
Here are the rest of the numbers:

image

Is this high level a potential cause, or just a side effect of everything else going on?
One more thing—tumors have been ruled out, except for some concerns regarding colon cancer, but we're still waiting on the colonoscopy results.

Also, I'm curious about these other values... why are they listed twice?
Nicholas Myers Nicholas Myers Active Member
163 messages
joined Jan 2012
#2236 ·
Mark Anderson90 said:Felix the Cat, can you interpret this for me regarding polycythemia?

First off, we have to ask if we're even looking at polycythemia here. For an American man, hemoglobin levels around 170 g/L are still technically within the range that covers 95% of the population (the upper limit for men is usually around 174 g/L).

That said, once hemoglobin climbs past 165 g/L (or above 170 g/L depending on which medical textbook you follow) and you start seeing symptoms linked to Polycythemia Vera—things like an enlarged spleen, aquagenic pruritus, high platelets, thrombosis, leukocytosis, headaches, or tingling—it makes sense to suspect the disease and start testing. That’s exactly what happened in your case.

However, since your erythropoietin levels are sitting in the normal range and the JAK2V617F test came back negative, Polycythemia Vera is looking unlikely. It’s practically ruled out.

It is worth noting there is another mutation (specifically in exon 12 of the JAK2 gene) that can show up positive in patients who are negative for JAK2V617F and have low erythropoietin.

Essentially, one or the other mutation is present in almost all patients diagnosed with Polycythemia Vera.

Given that your hemoglobin isn't elevated enough to definitively call it polycythemia rather than just being at the high end of the normal spectrum, it might be wise to first determine your total red cell mass to clear things up.

Furthermore, as Paul Walker5 pointed out a few pages back, because of those shortness of breath issues, you should probably undergo pulmonary function tests—spirometry, and maybe even a DLCO test. If this happens while you sleep, we could be looking at intermittent hypoxia caused by sleep apnea.

Also, your reticulocyte counts are slightly elevated, which raises the question of hemolysis. It would be smart to check your haptoglobin, bilirubin, and LDH levels to see if there are signs of increased red blood cell breakdown.

An electrophoresis of hemoglobin might also be worth considering to rule out any pathological hemoglobin variants.

As for infectious causes for your symptoms, I'd say the probability is slim. Your serology results point toward a past EBV infection that has already cleared.

That "white stuff" accumulating in your tonsil crypts is likely just debris—food particles and dead cells—and shouldn't be confused with a strep infection.

The nasal swab doesn't particularly support an allergic cause, though you can't entirely rule out allergic rhinitis based on that alone.

To wrap this up: the main question is whether this is actually polycythemia at all. Even if it is, Polycythemia Vera is a long shot. We need to look for answers elsewhere (starting with potential hemolysis and lung function).
Nicholas Myers Nicholas Myers Active Member
163 messages
joined Jan 2012
#2237 ·
Susan Smith said:Mr. Felix the Cat, if you wouldn't mind, could you clarify one blood result? A little context on the patient would help too.

First off, you can't rule out Wilson disease—that copper buildup issue—just by looking at serum copper or ceruloplasmin levels. Both can sit right in the "normal" range even when the disease is present. To get a real picture, you need to check copper in a 24-hour urine collection and schedule an ophthalmology exam.

Second, regarding the elevated ferritin and concerns about hemochromatosis (iron overload): we first need to look at transferrin saturation—which is calculated using serum iron and TIBC—as well as the SE and CRP levels. High ferritin isn't a smoking gun for iron issues alone; it can spike due to infection, inflammation, metabolic syndrome, or even malignancy.

Third, on the serum protein electrophoresis: seeing low albumin paired with high gamma-globulin is a classic pattern in patients with liver cirrhosis. Albumin levels drop because they are produced exclusively by the liver, and in cirrhosis, that synthetic function is compromised. Gamma-globulins can climb for several reasons in cirrhosis patients; you'd also need to check immunoglobulin levels to see if it’s specifically IgG or IgM that's elevated.

In the electrophoresis results, the values are listed as both a percentage and in g/L (absolute amount), which is why they appear twice.
Mark Anderson90 Mark Anderson90 Member
13 messages
joined Jan 2016
#2238 ·
Thanks for getting back to me!
My spirometry results came back totally fine—115/126/92. They haven't checked my bilirubin lately, but the last two times they did, it was elevated at 29.7 and 22. They didn't bother checking my haptoglobin, though. Sorry to be a pain and bug you with a total rookie question here: does hemolysis actually happen during anemia? Also, if it does, how is it that my Erc and Hgb aren't sitting right at the bottom of the range?

And the whole thing about my tonsils... I only brought that up because I heard they can basically act as breeding grounds for all sorts of health issues, just like teeth can.
Sandra Hernandez9 Sandra Hernandez9 Member
46 messages
joined Aug 2010
#2239 ·
Greetings, I would appreciate your insights on this matter.

My husband (32 years old, smoker, non-drinker, lean build) recently underwent a routine physical for work, only to receive a call later that afternoon stating his results were abnormal:

Enzymes
(S) AST (SGOT) - 64 (ref. range 11-38)
(S) ALT (SGPT) - 93 (ref. range 12-46)
(S) yGT - 63 (ref. range 11-55)

- Consequently, the doctor sent him back for follow-up bloodwork after three days (today):
AST - 40
ALT - 85
yGT - 60

The physician suggested these levels might be diet-related—even though our diet remains remarkably consistent—noting he does have a fondness for soda, though he isn't a frequent consumer. He has been referred for Hepatitis B and C markers as well as an abdominal ultrasound.

He recalls having to repeat similar tests during his military physical years ago, though everything was within normal limits back then.

Thank you in advance!
Sandra Hernandez9 Sandra Hernandez9 Member
46 messages
joined Aug 2010
#2240 ·
Sandra Hernandez9 said:Greetings, I was hoping to get some insight from you all.

My husband (32 years old, smoker, non-drinker, lean build) went for a routine employment physical, only to receive a call later that afternoon stating his results were off:

Enzymes
(S) AST (SGOT) - 64 (ref. range 11-38)
(S) ALT (SGPT) - 93 (ref. range 12 - 46)
(S) yGT - 63 (ref. range 11 - 55)

- Consequently, the doctor sent him back for follow-up bloodwork after three days (today):
AST - 40
ALT - 85
yGT - 60

She suggested it might be dietary—though his diet is remarkably consistent, nothing unusual... aside from a fondness for soda, which he doesn't consume frequently—and he was given referrals for Hepatitis B and C markers along with an abdominal ultrasound.

He recalls having to repeat similar tests during his military physical years ago, though everything was perfectly normal then.

Thank you in advance!

Hepatitis Markers
Hepatitis B surface antigen - non-reactive
Anti-HBs antibodies - 0.05 mIU/ml
Anti-HBc antibodies - non-reactive
Anti-HBc IgM antibodies - non-reactive
Anti-HBe antibodies - non-reactive
Hepatitis B e antigen - non-reactive
Anti-HCV antibodies - non-reactive

Enzymes
AST 39
ALT 77
yGT 59
Alkaline phosphatase 94 (ref. range 60-142)

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