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Psychotropic medication discussion thread

Started by Robin Myers91 · · 👁 695 views · 10K replies

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Participants Robin Myers91Eric Wood7Maria Gomez6crimsonhound80Tyler Ortiz6dustyscout41Andrew Stewart2George Ramos64Morgan Long49Jason Sanchez3briskgull27Charles Edwards8Brenda Allen2hollowtinker8bluecyclist28electricorca13David Kern14Ashley Morganwanderingscout13Sam Hall15coppergardenerCarl Thompson4Mark Stewartanalognomad762 …
Paul Newman5 Paul Newman5 Regular
251 messages
joined Oct 2012
#6121 ·
Paul Newman5 said:Been taking Ladomil 25 mg at night for a month now. It’s doing alright—helped lift the depression as much as it can in this timeframe and dialed back the jitters, which was a huge issue for me in the mornings. Because of that, I've actually been able to cut back on my Xanax intake, though I'm still using it. Still, it hasn't touched the anxiety much. I'm still struggling with getting to work and that constant dread of something going wrong once I'm there. Honestly, I just hate leaving the house in the morning. Even though the Ladomil keeps me calmer, my doctor prescribed the same nightly dose plus 5 mg (half a pill) of Escitalon at my checkup today. I've been lurking here for months and don't recall anyone mentioning it. If anyone has experience with it or knows anything, let me know. I read it's good for various types of anxiety and social phobia since it's an SSRI, but that's just what the pamphlet says. Real-world experiences would be helpful. Thanks.

Forgot to mention, Ladomil is still at night and Escitalon is in the morning—just realized it basically works out like I need to take both at night.
Jessica Fowler4 Jessica Fowler4 Active Member
51 messages
joined Jan 2013
#6122 ·
Kenneth Scott41 said:Does anyone else actually lose sleep over the idea of being on AD for the rest of their life?
Personally, I don't give it a second thought, because if it weren't for the AD, I might have been six feet under by now.
It helps me feel human again, so I really don't see the point in worrying about it.

Some people who know me a bit better—a few friends here and some folks I've connected with online—are aware that my daily routine involves more than just AD just to stay afloat... but even I have had to face the reality that this is likely a lifelong commitment.

But I'm not letting it get the best of me! 🙂

It doesn't bother me. I'm pretty sure I was just born with this disorder, so taking lifelong medication seems like the only logical path forward. That's actually what I'm aiming for and what I want. I just need to find the right chemical balance.
redcrane22 redcrane22 Active Member
90 messages
joined Jun 2012
#6123 ·
Kevin Bailey2 said:I’ve been on some pretty heavy meds for about a year now. Honestly, I’ve dealt with stuff even stronger than what I’m taking at the moment. To help my body handle it, I take vitamins, B complex, and milk thistle to keep my liver in check. Just had my blood work done recently, and everything came back perfect—even though I used to have a few too many drinks while on them.

The real question is how much your friend weighs and what they’re actually eating. If they’re overweight or living on junk food, the pills aren't even going to be a factor.

ideal weight 😁
I know it really varies from person to person depending on how their body reacts, but I wanted to mention that side effect too.
I actually ended up in the ER a little while ago, and since I can't find my paperwork right now, I'm wondering if they ran liver function tests. I went in because I was feeling pretty rough and they needed to figure out what was going on.
It turned out to be inflammation in my inner ear caused by a bad cold.
But that's not really the point; I'm more curious if they typically run those liver tests for you too—like, when they do a full blood panel, is that part of the standard procedure?
If it is, then everything is fine on my end, especially since I'm taking some medications myself. 🤷
Kenneth Scott41 Kenneth Scott41 Regular
457 messages
joined May 2009
#6124 ·
redcrane22, I suppose you might decide to show up here sometime, if you feel like it.😁
Robin Chavez6 Robin Chavez6 Newcomer
2 messages
joined Jan 2013
#6125 ·
Hey everyone! So, I was on Celexa (citalopram) for two years. It really helped with my depression, but man, it just left me feeling totally wiped out—super drowsy and exhausted all the time. I finally asked my psychiatrist to switch up my antidepressant, so he prescribed Lexapro (escitalopram, just like Cipralex or Elicea). I’ve been taking it for about a week now. I know it usually takes around two weeks to kick in, but I’d love to hear what you guys think... how did this one work for you? Right now, I'm dragging during the day but then tossing and turning with insomnia at night! Hopefully, it's just a side effect that clears up soon...
Jessica Fowler4 Jessica Fowler4 Active Member
51 messages
joined Jan 2013
#6126 ·
I’m still on memantine, and I occasionally mix in some amphetamines. The effects... they're definitely still there. Right now, I'm just waiting for my modafinil to show up in the mail. I mean, I’m not expecting any miracles or anything, but I'm curious, I guess. Once that's sorted, I might eventually try an opioid just to see what the deal is, but honestly, my real goal is to track down some JDTic or Zyklophin. Sadly, those are still just experimental, you know? I haven't seen any actual evidence of Zyklophin being tested on humans at all, and JDTic was only tried once before they shut the whole study down. Still, from what I can gather, JDTic might be obtainable... I'm trying to get in touch with people who have actually used it.

I mean, kappa opioid antagonists like JDTic sound like a total revolution in all these clinical trials... but maybe—just maybe—it’s all just massive hype because the results looked good in animal testing. It happens, right?

The alternative, I suppose, would be trying to get that same effect by using low doses to periodically agonize the kappa opioid receptors, which should cause desensitization... which I think would be similar to antagonism. For that kind of thing, Salvia divinorum seems like the perfect candidate... I could probably order some...

I guess I've really fallen down the psychonautics rabbit hole lately. :/
fadedbear92 fadedbear92 Veteran
1.1K messages
joined Dec 2008
#6127 ·
Robin Chavez6 said:Hey everyone! So, I was on Celexa (citalopram) for two years. It really helped with my depression, but man, it just left me feeling totally wiped out—super drowsy and exhausted all the time. I finally asked my psychiatrist to switch up my antidepressant, so he prescribed Lexapro (escitalopram, just like Cipralex or Elicea). I’ve been taking it for about a week now. I know it usually takes around two weeks to kick in, but I’d love to hear what you guys think... how did this one work for you? Right now, I'm dragging during the day but then tossing and turning with insomnia at night! Hopefully, it's just a side effect that clears up soon...

I actually found some info regarding your medication here:http://www.drsandic.net/archives/870
Jessica Chavez4 Jessica Chavez4 Active Member
67 messages
joined Jul 2012
#6128 ·
Is this thread strictly for prescription meds, or can I ask about things like melatonin? Or maybe some herbal options? Getting any sleep at all has become an absolute mission impossible lately.
copperheron18 copperheron18 Member
44 messages
joined Dec 2011
#6129 ·
I’m honestly at a loss for words... I’ve been on Xarelto for over two months now, and while there are stretches where I feel fantastic—where I can actually tell the medication is doing its job—there are also these days where the most trivial, ridiculous little things just throw me completely off balance. On those days, I spiral into this intense fear and panic; I become so depressed that I lose all motivation to do anything, and I end up needing Xanax just to get through it.

Is this kind of mood swinging typical when you're on an antidepressant? 🤷
I have absolutely no idea how an antidepressant is actually supposed to function, and I don't really have anyone to talk to about it. It just doesn't make sense to me why I have these days where I'm so incapacitated that I literally cannot pull myself out of bed, yet during other times, I can clearly feel that Xarelto is "working" well.
It’s as if some minor nonsense knocks me completely out of my element, leaving me to rely on a bit of "assistance" from Xanax to steady myself; it seems like the only way I feel okay is with both drugs working together.
There was actually a window of two or three weeks where I was functioning perfectly fine on just Xarelto alone. There weren't any major life events or shifts happening that would justify feeling anxious or fearful. Clearly, I'm in such a fragile state that even the smallest, most insignificant things set everything off in my head.
Andrew Peterson2 Andrew Peterson2 Active Member
148 messages
joined May 2013
#6130 ·
Quick question for you guys—can caffeine actually be put in the same category as these meds?? I mean, it’s super easy to get your hands on, totally over-the-counter... and honestly, I’ve noticed that if I load up on caffeine, I feel a lot happier or just have way more energy.
I usually go for pure caffeine pills or guarana. The guarana hits a little softer, so I just take a bigger dose of that. (The perk with guarana compared to regular caffeine is that it breaks down slower, so the kick lasts longer...

The thing is, those caffeine tablets just make me feel better... this job I have really gets under my skin sometimes, and let’s just say I don't always feel like showing up, but those pills boost my focus—plus, I actually feel upbeat and energized for once.

I don't drink coffee—just never liked the taste—so I just order caffeine pills through some online supplement shop.
Kevin Nguyen3 Kevin Nguyen3 Regular
425 messages
joined May 2013
#6131 ·
copperheron18 said:I’m honestly at a loss for words... I’ve been on Xarelto for over two months now, and while there are stretches where I feel fantastic—where I can actually tell the medication is doing its job—there are also these days where the most trivial, ridiculous little things just throw me completely off balance. On those days, I spiral into this intense fear and panic; I become so depressed that I lose all motivation to do anything, and I end up needing Xanax just to get through it.

Is this kind of mood swinging typical when you're on an antidepressant? 🤷
I have absolutely no idea how an antidepressant is actually supposed to function, and I don't really have anyone to talk to about it. It just doesn't make sense to me why I have these days where I'm so incapacitated that I literally cannot pull myself out of bed, yet during other times, I can clearly feel that Xarelto is "working" well.
It’s as if some minor nonsense knocks me completely out of my element, leaving me to rely on a bit of "assistance" from Xanax to steady myself; it seems like the only way I feel okay is with both drugs working together.
There was actually a window of two or three weeks where I was functioning perfectly fine on just Xarelto alone. There weren't any major life events or shifts happening that would justify feeling anxious or fearful. Clearly, I'm in such a fragile state that even the smallest, most insignificant things set everything off in my head.

Yes, those fluctuations—those shifts in mood—are entirely normal and to be expected. If you look at the patient information leaflet that came with your medication, it mentions that there is a certain risk regarding the emergence of suicidal thoughts or self-harm.
Effexor falls into a category sometimes labeled as a "heavy-duty" antidepressant, though, of course, it all depends on the individual.
It treats severe depression, but it requires time.
During that waiting period, regressions are quite common; you simply have to remain persistent. You could also have a conversation with your doctor, who might decide to add another medication (like AP or something similar) based on your symptoms, or perhaps adjust your dosage.
Effexor only shows its true benefits with long-term use; that is when you begin to react the way you expect to. Life isn't a constant, and neither is the illness, so you shouldn't expect miracles—but you can certainly achieve a high quality of life.
In fact, how much you expect from the process matters immensely... if you lower your expectations and realize that health arrives gradually rather than in a straight line, you will face fewer disappointments.
It is rare for serotonin syndrome (selective serotonin reuptake inhibitor issues) to occur, but one should keep it in mind because while it is extremely rare, it isn't impossible.
Even when you aren't experiencing major depressive episodes, you continue taking the Effexor until your doctor tells you otherwise. 😉
mistyseal11 mistyseal11 Regular
250 messages
joined Aug 2007
#6132 ·
Has anyone here actually dealt with Wellbutrin before?
During that first week, I swear it brought me back to life—like, it totally jumpstarted my will to live and everything...
But now, even though I’m feeling pretty level-headed, that drive to actually get stuff done just completely vanished...
It’s been about 4 weeks since I started taking it.
Do you think I should maybe ask my doctor about bumping up the dose? (I'm on 150mg right now)
Kevin Nguyen3 Kevin Nguyen3 Regular
425 messages
joined May 2013
#6133 ·
mistyseal11 said:Has anyone here actually dealt with Wellbutrin before?
During that first week, I swear it brought me back to life—like, it totally jumpstarted my will to live and everything...
But now, even though I’m feeling pretty level-headed, that drive to actually get stuff done just completely vanished...
It’s been about 4 weeks since I started taking it.
Do you think I should maybe ask my doctor about bumping up the dose? (I'm on 150mg right now)

Well, yes—that is precisely the point! This is roughly the window where it actually starts to kick in. For some people, it takes a bit longer, but we're talking the 4 to 6-week mark.
And listen, motivation isn't solely dependent on medication, is it? It's about lifestyle. When you were deep in depression, maybe lack of drive wasn't such an issue, but as your quality of life improves, suddenly that lack of motivation becomes a noticeable problem. Perhaps spend a little time educating yourself on the mechanics of motivation?
No, your dose shouldn't be increased. You stay right at 150 mg until your doctor decides it is time to slowly taper you off (and I mean slowly!!!).
You are responding well to the medication, so there is no need to go looking for trouble or reinventing the wheel. I am honestly just so glad to hear it's helping you.😉
fadedbear92 fadedbear92 Veteran
1.1K messages
joined Dec 2008
#6134 ·
mistyseal11 said:Has anyone here actually dealt with Wellbutrin before?
During that first week, I swear it brought me back to life—like, it totally jumpstarted my will to live and everything...
But now, even though I’m feeling pretty level-headed, that drive to actually get stuff done just completely vanished...
It’s been about 4 weeks since I started taking it.
Do you think I should maybe ask my doctor about bumping up the dose? (I'm on 150mg right now)

It worked for me for a few days, then nothing—zero, zilch, nada, niente.
Definitely talk it over with your doctor.
urbanskipper4 urbanskipper4 Active Member
144 messages
joined Apr 2011
#6135 ·
I know I’ve probably asked this before, but has anyone here actually tried Serdolect, or do you know someone who has?

Did they deal with any side effects? Specifically, I'm wondering if it caused weight gain or if they ended up feeling all stiff and zombie-like.
Thanks for the help, urbanskipper4.
Kevin Nguyen3 Kevin Nguyen3 Regular
425 messages
joined May 2013
#6136 ·
urbanskipper4 said:I know I’ve probably asked this before, but has anyone here actually tried Serdolect, or do you know someone who has?

Did they deal with any side effects? Specifically, I'm wondering if it caused weight gain or if they ended up feeling all stiff and zombie-like.
Thanks for the help, urbanskipper4.

Exactly how much are you taking? What's your dosage?
If you look at the fine print in the instructions, it clearly states that weight gain is one of the side effects.
And then there's tardive dyskinesia. Just... go Google it. A little.
By the way, this medication is typically used for treating schizophrenia.
I haven't personally taken it, but I know someone who switched from Seroquel to Serdolact (they were on over 600 mg of Seroquel, if I recall correctly—though I can't be entirely certain).
It's a heavy-duty drug. Lots of side effects.
urbanskipper4 urbanskipper4 Active Member
144 messages
joined Apr 2011
#6137 ·
Kevin Nguyen3 said:Exactly how much are you taking? What's your dosage?
If you look at the fine print in the instructions, it clearly states that weight gain is one of the side effects.
And then there's tardive dyskinesia. Just... go Google it. A little.
By the way, this medication is typically used for treating schizophrenia.
I haven't personally taken it, but I know someone who switched from Seroquel to Serdolact (they were on over 600 mg of Seroquel, if I recall correctly—though I can't be entirely certain).
It's a heavy-duty drug. Lots of side effects.


I'm not on it yet, just trying to do my homework beforehand. My doctor wanted to put me on it once to replace Seroquel because I gained 30 lbs from that stuff. For the last year, I haven't been on any AP, just antidepressants: Anafranil 1,1,2 and Aurorix 1,0,1. And honestly, I managed to drop 15 lbs, but I still have another 15 to go.
But my OCD has been getting worse. So now, I guess, I might need some damn AP.
🙂 I'm terrified of putting the weight back on.

I'd probably stick to a lower dose of Serdolect anyway since I was only doing 150 mg of Seroquel a day. But what good is a lower dose if I start eating like a starving dinosaur?🙂

I'll try bumping up the Anafranil, but knowing myself and how my symptoms act, I'm scared that won't be enough.

Thanks for the info, cheers from burnt-out urbanskipper4.🙂
urbanskipper4 urbanskipper4 Active Member
144 messages
joined Apr 2011
#6138 ·
Kevin Nguyen3: This whole tardive dyskinesia thing... it honestly looks pretty nasty.😲

Thank God there are newer APs out there that don't cause that. It's just sad—people are already struggling with their mental health, and then they have to deal with these involuntary facial grimaces, smacking their lips, and all that twitching. It's awful. I wouldn't wish that on anyone.
Kevin Nguyen3 Kevin Nguyen3 Regular
425 messages
joined May 2013
#6139 ·
urbanskipper4 said:I'm not on it yet, just trying to do my homework beforehand. My doctor wanted to put me on it once to replace Seroquel because I gained 30 lbs from that stuff. For the last year, I haven't been on any AP, just antidepressants: Anafranil 1,1,2 and Aurorix 1,0,1. And honestly, I managed to drop 15 lbs, but I still have another 15 to go.
But my OCD has been getting worse. So now, I guess, I might need some damn AP.
🙂 I'm terrified of putting the weight back on.

I'd probably stick to a lower dose of Serdolect anyway since I was only doing 150 mg of Seroquel a day. But what good is a lower dose if I start eating like a starving dinosaur?🙂

I'll try bumping up the Anafranil, but knowing myself and how my symptoms act, I'm scared that won't be enough.

Thanks for the info, cheers from burnt-out urbanskipper4.🙂

What exactly does a 150 mg daily dose look like?
No, well.
Try talking to them about Q-pin or Loquen instead. They work similarly to Seroquel (or at least they feel very similar), but they are much easier to tolerate, and you don't spend the entire morning feeling like a zombie.
They don't cause weight gain.
On what basis would you increase the Anafranil?
Just on your own whim?
Anafranil carries quite a few side effects; it isn't the most thoroughly researched option and is usually just prescribed as a general antidepressant at the start.
Hmm, when you take Aurorix, an antipsychotic is often prescribed alongside it. Any kind.
If you ask me... those two medications should never be taken together!!!
I suspect certain hormones get flushed out more intensely, which could trigger a complete counter-effect.
It is frankly unclear to me which doctor prescribed you such a regimen.
Do a little digging into those drugs and ask your physician about the interaction between those two antidepressants. And please, don't avoid AP; there are plenty available on the market today, and I’ve already suggested two that I know from experience actually work.
Don't be surprised if they hand you an anticonvulsant (like Lamal or something similar).
Kevin Nguyen3 Kevin Nguyen3 Regular
425 messages
joined May 2013
#6140 ·
urbanskipper4 said:Kevin Nguyen3: This whole tardive dyskinesia thing... it honestly looks pretty nasty.😲

Thank God there are newer APs out there that don't cause that. It's just sad—people are already struggling with their mental health, and then they have to deal with these involuntary facial grimaces, smacking their lips, and all that twitching. It's awful. I wouldn't wish that on anyone.

Look, I'm not saying you definitely have dyskinesia right now, but the risk factor is massive.
I actually just looked this up... you aren't supposed to mix Aurorix with that group of drugs known as the clomipramine-types.
And that is precisely what you are doing.
Which means, you really shouldn't be boosting those serotonin levels (or whatever the value is).
It’s what happens when people aren't properly educated about their meds—though, honestly, it isn't your fault. Your psychiatrist should have known better or at least double-checked the interactions.

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