Nicholas Johnson8 said:Please give me your thoughts on this lab result.
My mom, 74 years old, had a D-Dimer test because of some knee pain and slight swelling. The results showed a D-Dimer value of 1800. All her other blood work was within the normal range.
Her primary care doctor sent her straight to the ER immediately due to suspicions of thrombosis.
At the ER, they performed an EKG, a chest X-ray, and a venous ultrasound on her right leg (where the knee pain is located).
All those tests came back fine, and she was discharged home with explanations that DVT had been ruled out.
They just told her to follow up with her own doctor.
I'm a little worried about that high D-Dimer—what else could it be for, and is a leg ultrasound enough to truly rule out deep vein thrombosis?
Ugh, D-Dimers. They’re absolute lifesavers when they come back negative, but they are a total nightmare when they come back positive.
A value of 1,800... what are we even measuring here? $\mu$g/L? That seems most likely, but who knows. What is considered the "normal" threshold for whatever unit they used? If it's actually mg/mL, then anything up to 740 $\mu$g/L might be considered normal since the lady is over 50—you take age into account and multiply by ten for the upper limit. I ask because I'm used to seeing values around 0.5, so I really need to double-check those units, even though they're probably $\mu$g/mL.
If all the other findings were okay, does that mean the D-Dimer at the ER was also okay? Honestly, that's entirely possible.
You're stressing out, so why don't you do some digging on the medical sites yourself? Look, D-Dimers are incredibly sensitive, but they are notoriously non-specific, which is infuriating. It means they can be elevated because of practically anything, or even for no reason at all. You're the one seeing your mother in person; we aren't. For starters, go calculate the Wellsov score:
https://www.mdcalc.com/wells-criteria-dvtThen you'll have a better idea of what's going on.
An ultrasound can't settle everything here; neither can a CT or an MRI. An experienced doctor using ultrasound can look for signs of a clot in the major veins of the legs with pretty high probability, but even then, it's never 100%. The ER staff did their job by saying suspicion of DVT was ruled out based on their assessment, but that doesn't mean DVT itself is impossible.