LDN: A potential treatment for certain conditions?

Lawrence Castillo2, while I personally don't suffer from any such ailment, I spent an exhaustive amount of time scouring the internet for a potential remedy to assist a relative of mine. About six months ago, during a conversation in Florida with a retired American physician, he brought up LDN; I was initially quite skeptical, as the notion seemed entirely implausible to me. However, after dedicating roughly ten hours to deep research online, the documented evidence suggests truly remarkable results.

you wrote this in the "ulcerative colitis" thread, page 7,

While researching information online for my blog about two weeks ago, I stumbled upon the miraculous LDN (low dose naltrexone), which aids patients suffering from multiple sclerosis, Crohn, ulcerative colitis, lupus, various autoimmune diseases, and even certain types of cancer.

and you stated this right here.

Just as I noted in the colitis thread, I will reiterate: if this genuinely helps improve a patient's condition, then it is wonderful, though I cannot help but be reminded of the discussions regarding colloidal silver, where people also claimed a singular substance could serve as a cure.

And this is perhaps your most striking assertion:

I received word that some MS patients in America are already utilizing LDN for treatment. This is significant!

ha, what a character you are.🤣🤣🤣🤣😂😂😂

Look, Lawrence Castillo2, unlike colloidal silver, this stuff actually requires a prescription and is used specifically for treating addiction.
Doctors are the ones writing these scripts, so you really can't compare it to those random concoctions some people try to hawk on everyone.

Yeah, he told me the exact same thing—that glioblastoma responds just as well to this treatment...

...but hey, I’m just a hired gun for "Big Pharma," right? 😉

Who exactly is paying him, and what's the real motive behind it, is completely "irrelevant." ☕

That’s exactly why you have to take stuff like this with a grain of salt. You shouldn't be jumping into anything without talking to a doctor or a specialist first.

Which is precisely why I’m going to check with my immunologist first. I want to know if she’s ever heard of this and what her actual take is on the whole thing.

Thanks. Look, maybe I said some stupid stuff, but I would never be dumb enough to compare colloidal silver to this medication.

It’s entirely up to you if you want to try something new. Don't just take my word for it—go do your own homework. Check out the various links I’ve attached to my posts to see how effective this stuff actually is.

Angela Wright, listen: Dr. Bihari started using LDN and claimed it helps with glioblastoma. He was a highly respected doctor (passed away about five months ago), but hey, believe him or don't. It's your call. And no, nobody is paying me off. Why would they? The drug is dirt cheap. Also, I never called you a shill for Big Pharma; I just suggested you might be biased since you reject everything outright. But that's on you.

Leelo, I highly doubt any doctor here in the States knows anything about this. Missy, who lives in Norway, posted in the MS section that they set up a small organization there with a whole website dedicated to LDN. She showed all that info to her doctor and successfully convinced him to write her a prescription.

My advice? If you're interested, do your own research. You don't need to trust me; just decide for yourself after looking at the facts.

Sweet dreams to all!

urbanorca said:Thanks. Look, maybe I said some stupid stuff, but I would never be dumb enough to compare colloidal silver to this medication.

It’s entirely up to you if you want to try something new. Don't just take my word for it—go do your own homework. Check out the various links I’ve attached to my posts to see how effective this stuff actually is.

Angela Wright, listen: Dr. Bihari started using LDN and claimed it helps with glioblastoma. He was a highly respected doctor (passed away about five months ago), but hey, believe him or don't. It's your call. And no, nobody is paying me off. Why would they? The drug is dirt cheap. Also, I never called you a shill for Big Pharma; I just suggested you might be biased since you reject everything outright. But that's on you.

Leelo, I highly doubt any doctor here in the States knows anything about this. Missy, who lives in Norway, posted in the MS section that they set up a small organization there with a whole website dedicated to LDN. She showed all that info to her doctor and successfully convinced him to write her a prescription.

My advice? If you're interested, do your own research. You don't need to trust me; just decide for yourself after looking at the facts.

Sweet dreams to all!

🙂

Cut the assumptions. You haven't cited a single damn word I’ve written that suggests I’m rejecting anything outright.

There is massive money to be made in the low-end market.
Take AB pills, for example—they’re dirt cheap, yet big pharma makes their absolute highest margins on them.

Your aggressive, fundamentalist approach regarding LDNa is honestly infuriating and frankly off-putting. You go straight for the jugular, attacking anyone who dares to raise even a tiny question about your preferred theory. It’s hard not to notice how you pop up in all sorts of different threads—discussing various conditions that aren't even biologically related—only to peddle the exact same script every single time. It feels less like a discussion and more like a cultish crusade. Honestly, you’re acting like an Amway door-to-door salesman. In my experience—both online and in the real world—this kind of behavior usually points toward someone looking for personal gain. My issue isn't even about whether LDNa actually works; it's about your obnoxious way of handling it.

Look, if you want to believe it, go ahead—it’s your funeral. But honestly, the way you carry yourself makes this whole thing feel like nothing more than selling smoke and false hope to people who are already suffering. It's hard to take any of this seriously when there isn't a single shred of solid, undeniable evidence to back it up. We need more studies—and we need them to be massive in scale. What kind of person would actually stand behind such an aggressive stance?

There’s a massive difference between losing your cool when you’ve done everything by the book—you've met every requirement, you're entitled to your medication, and yet some bureaucratic red tape or systemic glitch is actively standing in your way—and then there's this whole other thing: acting like that over nothing more than some preliminary results. One is a justified reaction to a broken system; the other is just being dramatic about data that isn't even final yet.

Advice:
Get your head in the game and actually read what people are saying to you. If you don't practice some basic reading comprehension, this entire discussion is a waste of everyone's time. Even the mods have already pointed out that you need to get it together.

Angela Wright, thanks. It feels like we’re constantly talking past each other. All I want is to help people, yet I'm always getting hit with accusations about my "hidden motives" or whatever. Honestly, it doesn't surprise me; I've dealt with this kind of stuff before.

Here's an example—and yeah, I know it looks like I'm bragging (my bad!). Years ago, I started the "Books for America" initiative, donating free English books and magazines to various libraries across the US. We spent about $10,000 on it, and what did we get? A ton of backlash. People asking, "What's your angle?" or "What do you actually want from us?" The only place that truly welcomed the gesture was the Varaždin University of Computer Science (and seriously, thank you guys). For nearly five years now, we've been sending them materials with zero strings attached—feel free to check with them if you don't believe me. Huge thanks to them for even setting up a dedicated section for my donations here:

Again, the sheer amount of negativity coming out of America just baffles me. But hey, what can you do?

Anyway, I really dig that Leleeo slogan, the one Einstein used to say:

"A mind is like a parachute—it only works when it's open."

urbanorca said:Angela Wright, thanks. It feels like we’re constantly talking past each other. All I want is to help people, yet I'm always getting hit with accusations about my "hidden motives" or whatever. Honestly, it doesn't surprise me; I've dealt with this kind of stuff before.

Here's an example—and yeah, I know it looks like I'm bragging (my bad!). Years ago, I started the "Books for America" initiative, donating free English books and magazines to various libraries across the US. We spent about $10,000 on it, and what did we get? A ton of backlash. People asking, "What's your angle?" or "What do you actually want from us?" The only place that truly welcomed the gesture was the Varaždin University of Computer Science (and seriously, thank you guys). For nearly five years now, we've been sending them materials with zero strings attached—feel free to check with them if you don't believe me. Huge thanks to them for even setting up a dedicated section for my donations here:

Again, the sheer amount of negativity coming out of America just baffles me. But hey, what can you do?

Anyway, I really dig that Leleeo slogan, the one Einstein used to say:

"A mind is like a parachute—it only works when it's open."

I agree with it too.
Read it a few times and try to actually view yourself through that lens.

As for everything else, I don't have much to say, except maybe that you clearly missed my point.

Honestly, this thread should just be shut down immediately; instead of actually brightening my day, I find myself feeling completely drained by the sheer amount of negativity being spewed by certain individuals. For goodness' sake!
☕

wiredlynx33 said:Honestly, this thread should just be shut down immediately; instead of actually brightening my day, I find myself feeling completely drained by the sheer amount of negativity being spewed by certain individuals. For goodness' sake!
☕

Why get worked up? Everyone’s entitled to their own opinion. 😉

wiredlynx33 said:Honestly, this thread should just be shut down immediately; instead of actually brightening my day, I find myself feeling completely drained by the sheer amount of negativity being spewed by certain individuals. For goodness' sake!
☕

You're right. 🙏
I was actually waiting for someone to chime in and share their actual experience—you know, like "I took LDN for this long and felt like this" or "this part worked, but that part sucked." It would be helpful to get some real feedback.
Honestly, I don't care who's on anyone else's payroll. I'm on this forum for actual, firsthand experiences... nothing more, nothing less.
All this bickering is just going nowhere.
👎

Look, I'm with you. All this bickering is just stupid noise and doesn't matter. What actually matters? Someone coming forward with real-world experience using LDN. That’s the only thing worth hearing about!

My bad, I just stumbled onto some new info that might actually be useful for some of you:

The big-shot TV doctor Chris Steel over at ITV made this intense plea regarding LDN. He’s arguing it’s incredibly effective for tons of different conditions. Basically, if the NHS actually started using it more, we'd see way fewer sick people and save billions of dollars currently being wasted on expensive meds.

Video: http://www.youtube.com/watch?v=CVpjsDK0LPA

Even ABC aired a segment on LDN—really positive stuff too. It featured a deep dive with renowned doctors like Dr. Zagon and Dr. Jill Smith.

http://abclocal.go.com/wpvi/story?se...rts&id=6156884

You can even find info on LDN via the official Scottish Parliament pages:

http://www.scottish.parliament.uk/s3...09-PE1296D.pdf

If you're looking for sources, Skip's Pharmacy in Florida is one of the most well-known spots for LDN. Their website has some solid info:

http://www.skipspharmacy.com/home.php

They carry LDN in both 3 mg and 4.5 mg capsule doses.

Dickson Pharmacy in Glasgow does the same thing, and they've got it for about $27 a month.

http://www.ldnresearchtrust.org/uplo...s-pharmacy.pdf

Also, a few other sites are reporting that LDN is being used in treating glioblastoma.

Hope I didn't step on anyone's toes with this post.

And for the record, I am NOT selling LDN and I don't have any business ties to this medication whatsoever.

Just relax, urbanorca... don't let these trivialities wear you down. And even if you were actually trying to sell it, I would be the VERY FIRST person to buy it from you!! My thanks for the information...☕

Thanks, you too!

edit Scott Allen10
No, no... a post like this just won't fly... sorry... "they're selling it, it's the cheapest, here's the address"... please, just avoid writing like that.

I'm not sure if you're familiar with how things work here in the States regarding the law—it’s actually illegal to import medications you bought online directly into the US. You can only get your prescriptions through a licensed pharmacy, and those meds have to be specifically FDA-approved for the condition you're treating.

Scott Allen10, look, I just want to help people. I’ve spent ages digging into this, and I truly believe LDN could be a game-changer for so many folks.

It honestly breaks my heart to see people—especially the younger ones—dealing with autoimmune diseases. They end up in the hospital twice a year, and you have a 25-year-old girl telling you, "I'm done with everything, I'd rather just kill myself." Meanwhile, there's actually something out there, like LDN, that would most likely help her get her life back on track.

And yet, you’re standing there blocking people from getting the help they need. To me, that’s just messed up.

Angela Wright, I don't know much about that specific law, and yeah, I guess it's the same deal in other places like the UK. But think about it: someone is seriously ill, standard meds aren't doing a damn thing, but an alternative actually works. Now, because of some rule, they're supposed to just follow the law and refuse what actually helps? While their quality of life hits rock bottom or they literally die?

So they'd rather just die because they have to follow the rules? That's pure stupidity if you ask me. I read on one forum that half the people taking LDN in the UK are getting it through mail order, essentially bypassing the system. But let's be real—is any court actually going to have the guts to prosecute a sick person for trying to survive?

I don't get why everyone has stopped reading up and researching how useful LDN can be. Why is everyone so incredibly negative all of a sudden?

urbanorca said:Scott Allen10, look, I just want to help people. I’ve spent ages digging into this, and I truly believe LDN could be a game-changer for so many folks.

It honestly breaks my heart to see people—especially the younger ones—dealing with autoimmune diseases. They end up in the hospital twice a year, and you have a 25-year-old girl telling you, "I'm done with everything, I'd rather just kill myself." Meanwhile, there's actually something out there, like LDN, that would most likely help her get her life back on track.

And yet, you’re standing there blocking people from getting the help they need. To me, that’s just messed up.

Angela Wright, I don't know much about that specific law, and yeah, I guess it's the same deal in other places like the UK. But think about it: someone is seriously ill, standard meds aren't doing a damn thing, but an alternative actually works. Now, because of some rule, they're supposed to just follow the law and refuse what actually helps? While their quality of life hits rock bottom or they literally die?

So they'd rather just die because they have to follow the rules? That's pure stupidity if you ask me. I read on one forum that half the people taking LDN in the UK are getting it through mail order, essentially bypassing the system. But let's be real—is any court actually going to have the guts to prosecute a sick person for trying to survive?

I don't get why everyone has stopped reading up and researching how useful LDN can be. Why is everyone so incredibly negative all of a sudden?

You are stepping onto some very, very thin ice here.
I have to ask (and please forgive me if I'm being too blunt), but without formal medical, pharmaceutical, chemical, or biological training,
even with the best intentions in the world, are you really prepared to take responsibility for someone else's life?
I’m genuinely surprised by this. You’re old enough to know better, and since you aren't personally battling a major illness, you don't have that desperate drive for a cure driving your logic.
There is a massive difference between sharing information and encouraging critically ill patients to buy and use medications without any medical supervision.
A huge NO from me.
I am all for new therapies, and I always say every patient deserves choices. Medicine is constantly advancing, and doctors should definitely stay on top of new treatments... but I cannot support the uncontrolled use of drugs by the severely ill.
I totally get the desperation to feel better—believe me, if I could do things I can't do anymore to feel better, I'd do them in a heartbeat. But... we have to be careful not to cause harm.
Just because something worked for Barica and Mate doesn't mean it will work for us, especially since they are just anonymous users on a screen.

Ulcerative colitis is no joke. I haven't dealt with it myself, but my father has been fighting it for 30 years. We've had such hard times; he was even sent home from the hospital three different times because they said he was handling the hospital environment so poorly that he'd be more peaceful passing away at home. It was devastating.
Please don't joke about this. It is a serious disease. My dad is still here (he's been on meds for 30 years, isn't perfectly healthy, and has plenty of other issues, but he's independent!), but many of his friends from the hospital are gone.
Use your head.
Don't get defensive immediately. Neither the moderators nor Angela Wright are trying to be mean; they are just looking out for you and giving you a heads-up.

jadesailor14 said:You are stepping onto some very, very thin ice here.
I have to ask (and please forgive me if I'm being too blunt), but without formal medical, pharmaceutical, chemical, or biological training,
even with the best intentions in the world, are you really prepared to take responsibility for someone else's life?
I’m genuinely surprised by this. You’re old enough to know better, and since you aren't personally battling a major illness, you don't have that desperate drive for a cure driving your logic.
There is a massive difference between sharing information and encouraging critically ill patients to buy and use medications without any medical supervision.
A huge NO from me.
I am all for new therapies, and I always say every patient deserves choices. Medicine is constantly advancing, and doctors should definitely stay on top of new treatments... but I cannot support the uncontrolled use of drugs by the severely ill.
I totally get the desperation to feel better—believe me, if I could do things I can't do anymore to feel better, I'd do them in a heartbeat. But... we have to be careful not to cause harm.
Just because something worked for Barica and Mate doesn't mean it will work for us, especially since they are just anonymous users on a screen.

Ulcerative colitis is no joke. I haven't dealt with it myself, but my father has been fighting it for 30 years. We've had such hard times; he was even sent home from the hospital three different times because they said he was handling the hospital environment so poorly that he'd be more peaceful passing away at home. It was devastating.
Please don't joke about this. It is a serious disease. My dad is still here (he's been on meds for 30 years, isn't perfectly healthy, and has plenty of other issues, but he's independent!), but many of his friends from the hospital are gone.
Use your head.
Don't get defensive immediately. Neither the moderators nor Angela Wright are trying to be mean; they are just looking out for you and giving you a heads-up.

jadesailor14, thanks. Look, I don't have a medical degree, but I've spent countless hours digging into LDN. I've looked at what renowned doctors like Dr. Bihari, Smith, Zagon, and Goohilly have to say, read through several studies, and went through about 200 patient testimonials and stuff.

LDN (usually up to 4.5 mg) is a tiny dose of Naltrexone—a drug typically used in doses of 50 to 200 mg to treat alcohol and drug addiction. Not one single study or doctor claims it has dangerous consequences; there are almost zero side effects (maybe some insomnia). About 70% of people say it helped them, some even claim they're cured (meaning no more "flare ups"), and while about 10% feel it didn't work for them, nobody is claiming it made their condition worse.

There are even TV shows about this; some people call it a miracle drug. A leading TV Doctor in the UK, Chris Steel, made a heartfelt plea ("The NHS would save billions if they used LDN"), and there was even a petition signed by 14,000 people sent to Parliament over there.

But in the UK, about 95% of doctors refuse to prescribe it because it looks like Big Pharma is putting on the pressure to keep this cheap, effective drug from being used.

As for Big Pharma, it's just scandal after scandal—Avandia and Crestor (statins). Some estimates suggest that between 50,000 and 200,000 people in the US have died from those drugs. Now Avandia is banned in the UK. In the US, GlaxoSmithKline had to pay 60 million dollars to the first 700 people who sued them for the harmful effects, and there are still about 100,000 more people waiting in line for lawsuits.

I had massive problems with statins myself, and I stopped taking them three years ago, despite my doctor's advice (if I had listened to the doctor, maybe I wouldn't be bothering you guys here right now). I trust people's lived experiences and my own history with a medication way more than I trust doctors.

But hey, everyone should do their own research before jumping to conclusions. If I had an autoimmune disease or something similar, I already know exactly what I'd do.