Kenneth Price74
Active Member
61 messages
joined Oct 2007
Background Information
* history * Diagnostic criteria for schizoaffective disorder are as follows: 4
o An uninterrupted period of illness occurs during which a major depressive episode, a manic episode, or a mixed episode occurs with symptoms that meet criterion A for schizophrenia. The major depressive episode must include criterion A1, ie, depressed mood.
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o During the same period of illness, delusions or hallucinations occur for at least 2 weeks, in the absence of prominent mood symptoms.
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o Symptoms that meet the criteria for mood episodes are present for a substantial portion of the total active and residual periods of illness.
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o The disturbance is not due to the direct physiologic effects of a substance (eg, illicit drugs, medications) or a general medical condition.
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o The bipolar type is diagnosed if the disturbance includes a manic or a mixed episode (or a manic or a mixed episode and major depressive episodes).
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o The depressive type is diagnosed if the disturbance includes only major depressive episodes.
Physical Assessment
Physical: Obtain a complete medical history and perform a complete mental status examination, physical examination, and neurologic examination to assist with the evaluation and rule out other disease processes.
Although the mental status examination varies for each patient, examples of items to assess are listed below. Because of the variability of the presentation of the disorder, any or all symptoms of schizophrenia, bipolar disorder, or major depressive disorder may manifest depending on the presenting subtype.
* Appearance - Ranges from well-groomed to disheveled
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* Eye contact - Appropriate, increased, or decreased
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* Facial expression - Neutral, angry, euphoric, sad
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* Motor - Possible psychomotor agitation or retardation
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* Cooperativeness - May cooperate or may be uncooperative
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* Mood - Euthymic, depressed, or manic
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* Affect - Ranges from appropriate to flat
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* Speech - Ranges from poverty to flight of ideas or pressured
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* Suicidal ideation - May or may not be present. Remember that individuals with this disorder have a lifetime risk for suicide, which is significant. Inquiring about suicidal ideation at each visit is always important. In addition, the interviewer should inquire about past acts of self-harm or violence. Ask the following types of questions when determining suicidal ideation or intent. "Do you have any thoughts of wanting to harm or kill yourself?" "Do you have any thoughts that you would be better off dead?" If the reply is positive for these thoughts, inquire about specific plans, suicide notes, family history (anniversary reaction), and impulse control. Also, ask how the patient views suicide to determine if a suicidal gesture or act is ego-syntonic or ego-dystonic. Next, determine if the patient will contract for safety.
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* Homicidal ideation - May or may not be present. Inquiring about homicidal ideation or intent during each patient interview is also important. Ask the following types of questions to help determine homicidal ideation or intent. "Do you have any thoughts of wanting to hurt anyone?" "Do you have any feelings or thoughts that you wish someone were dead?" If the reply to one of these questions is positive, ask the patient if he or she has any specific plans to injure someone and how he or she plans to control these feelings if they occur again.
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* Orientation - To elicit responses concerning orientation (ie, person, place, time, situation), ask the patient questions, as follows. "What is your full name?" "Do you know where you are?" "What is the month, date, year, day of the week, and time?" "Do you know why you are here?"
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* Consciousness - The interviewer determines the levels of consciousness, rating them as: (1) coma, marked by a lack of responsiveness; (2) stuporous, where the subject responds only to pain; (3) lethargic, noted by persistent drowsiness; and (4) alert, indicating full awareness.
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* Concentration and attention - Instruct the patient to perform serial 7s by subtracting 7 from 100, repeating the process from each subsequent result. Additionally, request that the patient spell the word "world" both forwards and backwards.
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* Reading and writing - Have the patient compose a basic sentence containing a noun and a verb. Subsequently, ask them to read a specific sentence, such as "Close your eyes." This component of the MMSE measures the patient's capacity for sequencing.
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* Memory - To assess memory, utilize the following prompts. For remote memory: "What was the name of your first grade teacher?" For recent memory: "What did you eat for dinner last night?" For immediate memory: "Repeat these three words: pen, chair, flag." Instruct the patient to retain these words, then require them to repeat the list after five minutes have passed.
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* Delusions - These can manifest in various forms, including paranoid, grandiose, bizarre, or instances of thought insertion or withdrawal.
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* Hallucinations - Various types exist; auditory hallucinations are most prevalent, while gustatory hallucinations are the least common.
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* Insight - The range varies among patients.
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* Judgment - The range varies among patients.
Causes
While the precise cause of schizoaffective disorder remains unknown, it may involve factors similar to Schizophrenia, specifically the interplay of nature versus nurture. Currently, no specific genetic markers have been established. Environmental factors—such as malnutrition, viral infections, or complications during childbirth—may contribute. Furthermore, imbalances in neurotransmitters like serotonin, norepinephrine, and dopamine are suspected to play a role. Further research is required to fully clarify the etiology of schizoaffective disorder.