Amanda Vaughn3 said:The strongest thing out there for sleep is actually Circadin (extended-release melatonin).
Unlike other meds that just stretch out the duration without touching quality or depth, melatonin helps normalize the NREM phase—that's when the body actually recovers.
Pairing Fevarin with Circadin is the best way to drastically boost NREM sleep.
I've looked at polysomnography results from people taking all sorts of stuff—like Sanval—and those drugs just force shallow sleep.
People sleep for long stretches but never feel rested because stages 3 and 4 of NREM are basically non-existent. Melatonin, alone or paired with Fevarin, brings those deep phases (delta sleep, the actual restorative kind) back to baseline. You could potentially use another antidepressant alongside melatonin, but you really shouldn't be slamming benzodiazepines or zolpidem; they just increase quantity, not quality. The Japanese seem to understand better than anyone that five hours of deep, quality sleep beats ten hours of shallow tossing and turning.😉
So, I maintain that Dormicum remains the absolute strongest actual MEDICATION for sleep.
Circadin is such a strange hybrid—part drug, part supplement—it's relatively new to the scene and hasn't been studied nearly enough. (If I recall correctly, it only hit the market last year...)
It’s quite curious, isn't it? Why don't hospitals start using Circadin instead of all those standard medications they rely on... you know, things like Sanval, Zan, Cerson, and so on.
Perhaps we should be asking ourselves why?!
The one real upside is that you practically can't overdose on it... even taking 300 mg won't trigger any major adverse reactions.
But then again, just like any other chemical substance, melatonin carries its own side effects and shouldn't be taken without a doctor's supervision.
Furthermore, melatonin shouldn't be mixed with antidepressants, antipsychotics, benzodiazepines, or a whole host of other drugs.
Since the people here on Psychosofa are mostly individuals undergoing pharmacotherapy... discussing melatonin feels somewhat pointless.
Hmm, this claim regarding the REM sleep phase seems rather tenuous, given that some studies haven't actually shown those results.
And claiming that Fevarin yields the best results? That's just nonsense.