Chris Kim63
Member
23 messages
joined Mar 2016
Not sure if this is the right place for this, but if anyone can make sense of these results, I’d really appreciate the help.
My grandmother had breast cancer surgery back in 1968. They removed the entire breast then, and she went through chemo.
In 2008, she had surgery for a thyroid tumor.
The thyroid was removed, and she took iodine treatments.
About a month ago, she underwent surgery on her other breast—they had to remove the whole thing due to a tumor.
She was born in 1948. She’s incredibly anxious right now because of these findings, and she still has to wait two weeks to see the oncologist. Could someone help me interpret this? We just need some information to hold onto before the actual appointment and deciding on treatment.
Here are the results:
CLINICAL DIAGNOSIS: Ca mammae dex
Post-op status for right breast CDI (7/2017)
(3406/17, pT1c, pNx, Luminal B, HER2 negative
Post-op status for thyroid surgery due to papillary carcinoma (2008)
Post-op status for left breast neoplasm (1986)
Material type: consultation with immunohistochemical analysis
Specimen: 1. three paraffin blocks no. 3700/17 (label I E), right breast with secondary tumor, 2. right axilla with lymph nodes
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PATHOLOGICAL DESCRIPTION:
1. The specimen consists of three paraffin blocks, labeled IE (pathology lab, biopsy), received for biopsy and additional immunohistochemical processing.
Microscopic examination shows a breast measuring 17:15.6 cm, with an area partially covered by skin measuring 19:9.5 cm. Three lesions, 0.5–0.8 cm in diameter, were found on the skin surface, which histologically correspond to hemangiomas. At 3.5 cm from one resection margin, there is an old postoperative scar measuring 4.5 cm. On a cross-section of the breast, beneath the scar, there is a hollow formation 3.5 cm in diameter filled with bloody content. Histologically, this is a blood-filled pseudocyst accompanied by an extensive foreign body-type inflammatory reaction. Surrounding this hollow area is a yellowish, firmer region 6.5 cm in diameter, which histologically corresponds to fat necrosis. Located 0.3 cm from the second resection margin, opposite the old scar, is a nodule 0.8 cm in diameter. Histologically, this is a tumor composed of pseudo-glandular formations, strands, and solid clusters of atypical epithelial cells with hyperchromatic nuclei and occasionally prominent nucleoli, with the presence of desmoplastic stroma. No mitosis was observed in 10 high-power fields of the tumor. There is no lymphangioinvasion. Immunohistochemically, the tumor cells are positive for Estrogen (95% of tumor cells) and Progesterone (30% of tumor cells). HER2 is 0 (negative). Ki-67 is 5%.
Molecular carcinoma type, St. Gallen, 2013, Luminal A
2. Fatty tissue specimen, measuring 9.5:7:6. A total of 18 lymph nodes, ranging from 0.4–1.2 cm, were found and appeared normal.
Methods: HE, Estrogen, Progesterone, Ki67, HER2