Lab results - looking for opinions [PLEASE READ 1ST POST]

Now, let’s be clear: this is nothing more than a massive assumption. And we all know that an assumption is often the root of every single mess you can imagine—this particular assumption is basically the granddaddy of all screw-ups—but regardless.

If that "heart murmur" (regardless of how intense it is on a scale of 1 to 6, or I to VI for those who prefer Roman numerals) was actually caused by aortic valve stenosis, and if there aren't any signs of pancytopenia (meaning low leukocytes and platelets), then simple hemolysis caused by highly turbulent blood flow through a severely calcified aortic valve is actually a plausible explanation. Honestly, I’ve even personally seen a case like that before. Of course, I have to stress again that this is purely speculative, so none of this is necessarily correct. Pneumonia could also be a factor, though I find that less likely at this moment, especially if Mom isn't currently battling full-blown, severe sepsis.

Thanks for the help. It isn't sepsis.

Can anyone help me out? I've been dealing with anemia for a long time now—like 4 years—so if someone could take a look at my results and give me some answers, I’d really appreciate it!!

Here are the results. Everything looks normal except for the MPV, which is running a bit high compared to the reference range.

Thanks.

cosmiccobra2 said:Can anyone help? I've been dealing with anemia for about four years now. I would be really grateful if someone could help me make sense of these results and give some insight!!

Here are the results. Everything is within the normal range except for the MPV, which is running high compared to the reference interval.

Thanks.

Hello,

As far as I can recall—since the image isn't displaying anymore—you don't have anemia based on these current findings. An isolated deviation in MPV shouldn't mean much as long as your platelet count and function look solid.

Hey everyone, especially shoutouts to Nicholas Myers and brightgull95!

You guys know me—I’m not gonna dump every single lab result and diagnosis here because you'd be reading forever.

The big headache right now is Vitamin D. Ever since I started seeing my endocrinologist back in 2017, my levels have been sitting way below the baseline. Between working an office job and having a huge house that needs constant cleaning, I basically never see the sun. Not sure if that was the main culprit, but my Vitamin D was trash every single time I got bloodwork done. I tried taking it in capsules, then switched to a spray. Basically, I was super consistent with it. A few months ago at my checkup, here’s what showed up:

VitD3 19.9 (20 - 150)

Ca 2.58 (2.14 - 2.53).

My endocrinologist actually called me to say that because my Calcium is creeping up, I need to stop the Vitamin D supplements immediately. We’re supposed to meet for a follow-up to figure out a game plan.

I haven't had the follow-up yet because they're all out on vacation. What really has me spiraling, though, is how sick I am all the time. Constant viruses, sore throats, coughing, runny nose, stomach bugs... as a total amateur, I’m thinking my immune system is just completely trashed.

Ever since COVID-19 hit, I've been working from home and being extra careful so I haven't caught it yet. I didn't get vaccinated because my immunologist recommended I hold off. I'm not some anti-vaxxer or anything, I just panic easily, and once my doctor told me "don't get the shot for now," that was it for me.

I read a ton about this, and everything says people with low Vitamin D struggle with immunity and face more complications with COVID-19. So, how do I supplement without my Calcium spiking? And what else can I take to fix my immune system?

Any advice is welcome. Thanks in advance.

Hi everyone, I’m looking for some help interpreting my lab results. I’m a bit worried about my platelet counts—they’ve been running high for about two years now, though they haven't actually crossed the upper limit yet. This started following my vaccine and after I recovered from COVID-19.
My doctor says the numbers look great, though.
On June 16th, I had a Letz procedure on my cervix, and my bleeding patterns have stayed normal since then.
As for underlying issues, I deal with GERD and managed asthma.
I recently had blood work done because of some pain in my lower right abdomen. It actually went away for a bit, but now it’s starting to flare up again.
An abdominal ultrasound came back totally clear, aside from a lot of gas and some fullness in my intestines.
The doctor thinks the pain might be linked to the Letz procedure or just general bloating.
I also feel exhausted quite often, so my doctor put me on Vitamin D.

Best,

Hi there! I just got my blood work back, so here are the results:

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My creatinine is slightly above the limit, and I think this is the third time it’s been elevated like this. My ALT seems to be up for the fourth time too, I guess. Monocytes are high for the first time. Is there a specific reason for this, or is it maybe just a minor deviation? I deal with GERD and hypertension, and I usually struggle with constipation whenever I have iron deficiency.

Kimberly Morris said:Greetings everyone, especially doctors Nicholas Myers and brightgull95!

You know me; I won't list every single lab result and diagnosis because you’d have far too much to read.

My current issue is Vitamin D. Since I started seeing my endocrinologist back in 2017, my Vitamin D levels have consistently sat well below the lower limit. I work an office job, and I have a large house that requires constant cleaning, so I’m rarely out in the sun. I'm not sure if that was the primary cause, but my Vitamin D levels were low every single time I had bloodwork done. I've tried supplements in capsules and sprays. Basically, I've been taking it regularly. At my last check-up with the endocrinologist a few months ago, here were the results:

VitD3 19.9 (20 - 150)

Ca 2.58 (2.14 - 2.53).

The endocrinologist called me and said that due to the rise in Ca, I need to stop taking Vitamin D. We’ll meet at the follow-up to discuss how to proceed.

The follow-up hasn't happened yet because they're away on vacation. What worries me is that I am constantly sick. Constant viral infections, sore throats, coughing, runny noses, stomach bugs. As a layman, my conclusion is that my immune system is shot.

Since COVID-19 started, I've been working from home and taking maximum precautions, so I haven't caught that yet. I didn't get vaccinated based on my immunologist's recommendation to hold off. I'm not an anti-vaxxer, just someone who panics a bit—when my specialist once told me, "don't get vaccinated for now," that stuck in my head.

I read a lot about this, and it says anyone with a Vitamin D deficiency faces immune issues, complications from COVID-19, etc. How can I supplement without causing my Ca to rise? What should I take for immunity?

Any advice is welcome. Thanks in advance.

Dear lady,

Taking Vitamin D supplements can further increase calcium levels because it stimulates calcium absorption in the intestines. Unfortunately, the ratio of calcium to Vitamin D is unfavorable in your case, but a total calcium level of 2.58 mmol/l is only slightly elevated. It would be ideal for your Vitamin D levels to be higher; yours was measured at 19.9 ug/l, while the recommendation is above 20 ug/l or ideally above 30 ug/L. Note that the units are in ug/l, not nmol/l, which is how concentration is most commonly expressed; this likely caused some extra confusion, as when expressed in nmol/l, the recommended level is above 50 nmol/l.

I don't believe your Vitamin D levels are so critical that you cannot wait for the final processing of your results.

This specific constellation of findings (low Vitamin D, high calcium) is known to occur in hyperparathyroidism, primarily primary hyperparathyroidism, though secondary hyperparathyroidism can sometimes be seen alongside a Vitamin D deficiency—though in those cases, calcium levels are usually normal or low. If a diagnosis of primary hyperparathyroidism is confirmed, it may be possible to take Vitamin D with extreme caution, and generally, significant hypercalcemia does not occur.

There are no scientifically proven supplements that improve immune system function; therefore, the best approach remains adequate sleep, physical activity, and a varied diet.

Sam Taylor22 said:https://i.postimg.cc/2SSrs02D/Screenshot-20220818-142844-Yahoo-Mail.jpg

Hello, I'm looking for an interpretation of these results. I'm concerned about my platelet counts; they've been elevated for two years now, though never above the upper limit. This started following my vaccine and recovering from COVID-19.
My doctor says the levels look great.
On June 16th, I had a Letz procedure on my cervix; bleeding patterns have remained normal since then.
Regarding medical history, I deal with GERD and controlled asthma.
I recently had blood work done due to pain in my lower right abdomen. The pain actually subsided for a bit, but it keeps coming back periodically.
An abdominal ultrasound showed everything was fine, aside from significant gas and full intestines.
The doctor attributes the pain to the Letz procedure and the bloating.
I also experience frequent fatigue, so my doctor prescribed Vitamin D supplements.

Best regards,

Hello,

Looking at the results you provided, I agree with your physician—they look normal. The only thing is that your Vitamin D levels could be higher, so I think prescribing a supplement is a sound decision.

Peter White80 said:Good day. I had some blood work done; here are the results:

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My creatinine has hit this elevated level—just slightly above the limit—for the third time now. My ALT seems to be high for the fourth time as well. Monocytes were flagged once. Is there an underlying reason for this, or is it just a minor fluctuation? For context, I deal with GERD, hypertension, and struggle with constipation whenever I have iron deficiency.

How old are you? Are you currently taking any medications? Also, how is your blood pressure being managed?

Maria Fisher46 said:How old are you? Are you on any medications? How is your hypertension being managed?

Hi there,
I'm 18. I take Atenolol 25-50 mg for my blood pressure and Esomeprazole for gastritis. My last home monitoring:
Home Monitoring (August 2, 2022) (41/40 readings)
Max systolic: 160 mmHg, Max diastolic: 115 mmHg
Average blood pressure readings (mmHg):
Overall 140/68 (95th percentile 80)
Daytime 144/70 (95th percentile 85)
Nighttime 127/62 (95th percentile 76)
Nighttime BP drop (%):
Systolic 11.3% (normal)
Diastolic 12% (normal)
My hair has also thinned out quite a bit since I started the beta-blockers. Mostly on the crown. It grows slower now too. (L65.0 Telogen effluvium) Plus, I have tinnitus and sometimes feel a little dizzy since my blood pressure was discovered.
Also, all my blood work results have this note: "Serum slightly lipemic."

Here are some other results if you're interested: View on imgur

Peter White80 said:Dear Sir,
I am 18 years old. I take Atenolol 25-50 mg for blood pressure and Esomeprazole for gastritis. My last BP monitoring:
BP Log (August 2, 2022) (41/40 readings)
Max systolic: 160 mmHg, max diastolic: 115 mmHg
Average blood pressure values (mmHg):
Overall 140/68 (95th percentile 80)
Daytime 144/70 (95th percentile 85)
Nighttime 127/62 (95th percentile 76)
Nighttime BP drop (%):
Systolic 11.3% (normal)
Diastolic 12% (normal)
My hair has also thinned significantly since starting the beta-blockers. Mostly on the crown. It grows back slower, too. (L65.0 Telogen effluvium). Additionally, I have tinnitus and occasional dizziness ever since my blood pressure was diagnosed.
Also, all my blood work includes this note: "Serum slightly lipemic."

Some other results if you are interested: View on imgur

Beta-blocker therapy isn't typically the first line of defense for hypertension in pediatric patients, so I assume your condition began before age 18. I later saw in another thread that various antihypertensives were tried previously, and only Atenolol proved effective. What was the reasoning behind the immunological tests you attached? And regarding the nephrology workup—I assume that was done to rule out renal causes for the hypertension?

It might be more productive to move this discussion to a single thread, perhaps one specifically dedicated to arterial hypertension. Otherwise, the conversation gets diluted and harder to follow.

Hey there.
So, we went ahead and redid the blood work just like you suggested, though I guess we're running a little bit behind schedule on the timing.
Looking at the results, the erythrocyte and hematocrit levels are still showing this tiny, slight dip below the normal range, but the hemoglobin, iron, and ferritin all look perfectly fine. There’s a minor little deviation in the white blood cell count, and predictably, the IgA is still running low.

The hematologist actually mentioned that since everything is basically holding steady without any major changes, we might be able to start spacing out the check-ups a bit more. What do you guys think about that? Is that a reasonable move?

Emily Ortiz27 said:Hey there.
So, we went ahead and redid the blood work just like you suggested, though we were a little behind schedule on getting it done.
The erythrocyte and hematocrit levels are still showing a very slight dip below the normal range, but the hemoglobin, iron, and ferritin levels look fine. There’s also a tiny bit of deviation in the white blood cell count, and as usual, the IgA is low.

The hematologist actually thought we might be able to scale back the frequency of the check-ups now, since everything seems pretty much stable. What do you guys think about that?

There’s one more important thing to add—the cytology smear just came back, and it included a note saying we should contact the hematologist.
I’m going to reach out to them today, obviously, but I’d love to get your take on this too.
What exactly should we be looking for here? In what direction do you think this finding might go, or could this just be some one-time fluke that doesn't mean anything?

Here I am again....

We got called back to the outpatient clinic pretty quickly to go over some follow-up results, though we haven't actually received all of them yet.
From what we do have in hand, I can see that the erythrocytes are still a tiny bit low, but honestly, it’s not even a major deviation from the reference range (4.20 (4.34-5.47)), nor is the hemoglobin (120 (121-145)) or the hematocrit (0.355 (0.366-0.452)); the hematology specialist didn't even bother asking any questions or making a big deal out of it. The percentage of neutrophilic granulocytes is also minimal, staying either just below the reference range or right at the bottom edge for quite a while now (today it was 34%, while the absolute count is within the normal range at 2.29).
The urine test came back clean, aside from an erythrocyte finding of 10/umol/L (1+) and a microscopic sediment exam showing 3 erythrocytes /mm^3.
The main focus during the check-up was on those atypical and reactive lymphocytes found in the blood smear, so they're going to repeat the smears and an ultrasound in a couple of weeks to compare everything against the other results we're still waiting on and the ones we got last time.

So, that’s the summary of where things stand, and I should probably mention that the kid is actually doing great—he's cheerful, well-rested, and has a totally healthy appetite.

Emily Ortiz27 said:All in all, that's the gist of it. It’s also worth noting that the kid is actually doing quite well—bright, well-rested, and eating normally.

Ma'am,

I think that, regardless of how well the child is doing and the lack of symptoms, it isn't time to scale back the checkups just yet. We should maintain the current schedule. These results aren't surprising given the disease or, since we don't have molecular confirmation yet, the spectrum of possibilities under consideration. Still, caution is necessary, and regular monitoring remains essential.

Maria Fisher46 said:Hi there,

Looking at the results you shared, I actually agree with your doctor—everything looks pretty solid. The only thing is that Vitamin D level could definitely be higher, so I think prescribing some supplements is a smart move.

Thanks,

Best of luck.

Hello,

Could you please help me interpret this result? I'm wondering if there are any signs of insulin resistance based on this insulin level after 120 minutes...
In other results from last week, my ferritin was 11.3 ng/l (ref. 13.0-150) and iron was 90 ng/l (ref. 33-193)

Thank you so much in advance.

I’m feeling a bit thrown by my biopsy results. I recently underwent a gastroscopy, and the findings were as follows:


And here is the report from the pathologist...


What’s really tripping me up is this—the pathologist's report states the material is consistent with gastric mucosa, yet it also mentions that part of the sample contains normal stratified squamous epithelium. From what I’ve gathered during my own research, the stomach lining should be composed of simple columnar epithelium, right?

Does this mean we're actually looking at an esophageal sample, and if so, could this intestinal metaplasia indicate Barrett's esophagus?

Dear Sir or Madam,

Could you please provide some clarification regarding these lab results?

Thank you.

In the bone marrow sample, cells the size of lymphocytes (14%) and monocytes are present.
The granulocyte count is at 8%, while the granulopoeia stands at 78%. Based on the mononuclear cell analysis (which includes lymphocytes and monocytes)...
The findings indicate that T+NK cells make up 38%, while B-cells account for 10%. Additionally, monocyte phenotype cells represent 19% of the total.
Immature myeloid cells at 17%, which includes 9.5% of cells exhibiting a myeloblast phenotype.
Out of the total number of stations in the sample, the proportion of T+NK stations stands at 8%, while B-type stations account for 2%, and the station type...
Monocytes at 4%, immature myeloid cells at 3.8%, including 2% of cells with that specific phenotype.
Myeloblast, along with findings showing granulopoiesis at 78%. The results show no pathological signs.
Mononuclear cells of the bone marrow.