Raymond Ortiz69
Member
20 messages
joined Jan 2015
Hey everyone,
So, I finally got officially diagnosed with anxiety and depression last week, and I actually started my medication yesterday.
By the way, I honestly thought the diagnosis would be clinical depression plus panic disorder—mostly because I feel like I check every single box in the manual—but it turns out they prescribed me an antidepressant specifically for clinical depression, which I guess just covers everything? Like a 2-in-1 deal?
Anyway, my new little companion is called Valdoxan (25 mg). It’s agomelatine, which is basically to paraphrase the medical jargon: / it stimulates melatonin receptors while blocking the ones that usually activate serotonin, which eventually leads to a boost in dopamine and norepinephrine in the mood-regulating part of the brain.
At least, that's what it says. You should probably look it up yourselves though! 😁
To be honest, I'm still a little fuzzy on whether it actually affects serotonin levels directly by making more available, or if it works differently.
I haven't found much personal experience online regarding Valdoxan, so I figured I'd report back here and let you all know how it goes. From what I've gathered, reviews range from "this is life-changing" to "complete waste of money." So... I guess we'll see. The main thing is that it doesn't fall into the usual categories like an SSRI or SNRI.
It's also pretty pricey. Even with Medicare covering some of it, I ended up paying about $33 for a month's supply.
The big concern seems to be its potential impact on the liver, so I'm really crossing my fingers that everything stays healthy there. Aside from that, it's supposedly not supposed to have many significant side effects.
Oh, and apparently, it isn't addictive—the literature says you can just stop taking it without having to do a slow taper.
As far as I can tell, it's mainly used in Europe (and I think Australia too), and while it started rolling out in the US a few years ago, I couldn't find any definitive info on its status here... at least not easily.
My doctor also noted Insomnia on my chart, though my real struggle isn't necessarily sleeping too little, it's just that my brain refuses to shut off at night, then suddenly kicks into high gear early in the morning. I get enough hours, technically... but the quality is off. That's why I was given Valdoxan, since I take one 25 mg tablet right before bed. The melatonin component should help reset my circadian rhythm.
I took it yesterday, and wow, within ten minutes I was yawning, and then I slept like a baby. I had absolutely no idea what was happening around me—no crazy dreams, no nightmares, no tossing and turning. Just a perfectly normal wake-up when my alarm went off... So, hey, at least that's a win to start with.
Oh, right, I'm also taking 1mg of Lorsilan (once in the morning and once at night). This morning was a total fog; I had to head out and take the bus, and I felt like a complete zombie stumbling through the day. Does anyone know if there's an adjustment period for benzodiazepines where the body gets used to them and that initial "brain fog" starts to lift?
Sending love to you all,
😉