Psychotropic medication discussion thread

Does anyone out in San Francisco happen to have any Ritalin or Concert? If you do, please just shoot me a private message.

So, about 5 days ago I accidentally took an extra 10mg of my antidepressant. Usually, I’m on 20mg twice a day plus Xanax SR x2, but I guess I mixed things up and grabbed some Cyprus instead of my Xanax...

The first night I just slept through it, but for the last three days, my stomach's been acting up and I've been getting these panic attacks—mostly just feeling super nauseous and breaking out in sweats. I'm thinking maybe it's just because I hit 30mg that day instead of 20mg, so it's probably just my body reacting and it'll eventually die down.

Anyone else dealt with something like this? Maybe shoot me a PM if you have. 🙂

Thanks

I haven’t ever taken too much Cipralex, but I am definitely feeling those exact symptoms right now during this initial adjustment phase
I assume the patient info leaflet covers what to do in case of an overdose (likely just contact a doctor)

After all that restlessness and anxiety, things finally settled down last night and I managed to get a solid 8 hours of sleep. I really hope it stays that way!
I have some Xanax to help me relax, and my doctor even prescribed Ambien when I complained about the insomnia, but I’m not a huge fan of the side effects. I've never actually used a hypnotic before, just anxiolytics.
What works best for you guys when it comes to getting some sleep?

Lexapro works wonders for me.
I didn't deal with any side effects at all, not when I started and not even when I stopped on my own 🙄.
It actually took about 10 to 15 days before I felt the real impact.
I’d only touch Xanax in extreme, rare situations.
If you're struggling to sleep, just stick to Melatonin for a few days until your rhythm gets back on track.

It might really depend on where you're starting from. For me, the issue isn't even primarily depression; it’s more about the anxiety and those relentless, obsessive thoughts. The literature also mentions that these symptoms can actually spike when you first start... and honestly, without a little extra anti-anxiety help, it feels absolutely terrifying.
You just have to power through this adjustment phase.
I'm going to try to steer clear of Sanval because I'm terrified of hallucinations or other side effects—one of my biggest phobias is the idea of losing touch with reality and becoming psychotic.😁

Sleep is basically pure peace and relaxation. I usually put on some chill, mellow music right before bed 😉 autogeni training works wonders too. As for pills, when I'm tossing and turning, honestly, nothing seems to help 🤣

dustyangler2 said:Sleep is basically pure peace and relaxation. I usually put on some chill, mellow music right before bed 😉 autogeni training works wonders too. As for pills, when I'm tossing and turning, honestly, nothing seems to help 🤣

San Val always knocks me out cold. I sleep through the whole night perfectly fine, but I'm starting to think I've become totally dependent on it... I can't even get to sleep without it anymore.

Is there anyone out there currently relying on Serdolekt who might be willing to share their honest take on the drug? I’m looking for some actual insight—not just the glossy brochure version—regarding how it actually feels to use it.

Larry Lewis said:Is there anyone out there currently relying on Serdolekt who might be willing to share their honest take on the drug? I’m looking for some actual insight—not just the glossy brochure version—regarding how it actually feels to use it.

USA
Abbott Labs First applied for U. S. food and drug Administration approval for sertindole back in 1996,[1] but they ended up pulling the plug on that application in 1998—mostly due to worries regarding an increased risk of sudden death caused by QTc prolongation.[2] To give you an idea of the scale, in one trial involving 2,000 patients, 27 people passed away unexpectedly, which included 13 sudden deaths.

Europe in Europe
Over in Europe in Europe, the drug was actually approved and sold in 19 different countries starting in 1996,[3] but its authorization was suspended by the Food and Drug Administration in 1998[7], leading to it being pulled from the market entirely. Fast forward to 2002: after looking at fresh data, the FDA's advisory committee suggested that Sertindole could be reintroduced for restricted Use in clinical trials , with strong safeguards including extensive contraindications and warnings for patients AT risk of cardiac dysrhythmias, along with dropping the max dose from 24 mg to 20 mg (unless there's a really good reason not to) and requiring strict ECG monitoring both before and during treatment.[8][9] Eventually, the marketing ban was lifted in 2005.[10]

http://en.wikipedia.org/wiki/Sertindole 😲

http://www.facebook.com/topic.php?ui...88&topic=14057 😲

The maker of the antipsychotic med sertindole (Serdolect) chose to voluntarily stop making it available. This move came down to serious concerns regarding reports of heart arrhythmias and sudden cardiac death linked to its use.
(Reference: (GBRCW) Communication, 02 Dec 1998)

Safety and serious adverse events
Out of the 97 serious adverse events recorded, 10 were fatal. This included 2 suicides, 3 sudden deaths (specifically 2 heart attacks and 1 pulmonary embolism), 4 "other" deaths (one pulmonary embolism, one unspecified intoxication, one heart attack, and one mesenteric artery infarction), plus 1 death where the cause couldn't be determined.

Hey there! How's it going?

So, I’ve been on Prozac for about seven months now. It started because of the whole panic attack thing—you know, that constant, gnawing anxiety and those intrusive thoughts that just won't quit. It's been quite a journey so far.🙂.
My therapist told me I’m going to have to be on Prozac for at least six months before we even start looking into psychotherapy. I guess that's just how it goes, right?
In the meantime, I got a massive amount of crap from her, and now I’m stuck without a psychiatrist.🙂.
So, I’ve been on these pills way longer than I was originally supposed to be. But honestly? I feel great. And if I’m being real, the idea of stopping the meds and having to face those same old panic attacks all over again... yeah, that sounds like a nightmare I'm not ready to revisit.🙂.

Quick question—does staying on antidepressants longer than originally prescribed actually do any harm?
Sometimes I totally blank on taking my pill until late in the afternoon, and honestly? I don't even notice a difference... I guess it doesn't really move the needle for me one way or the other.

I honestly can’t tell the difference whether I’m sipping a Schwarzkopf here or over there—it all tastes exactly the same to me.

I feel like I’m doing too well, and honestly? It’s kind of terrifying. I know this probably sounds completely ridiculous, but am I overdoing it with the Prozac? Like, is it actually possible to have too much serotonin? I guess I’m just spiraling a little bit because things feel... fine. Too fine.

Honestly, if you ask me, I could probably drink them forever. I swear, they make me feel like my old self again.

Thanks in advance for any help or answers you guys can throw my way!

wanderingcyclist20 said:Hey there! How's it going?

So, I’ve been on Prozac for about seven months now. It started because of the whole panic attack thing—you know, that constant, gnawing anxiety and those intrusive thoughts that just won't quit. It's been quite a journey so far.🙂.
My therapist told me I’m going to have to be on Prozac for at least six months before we even start looking into psychotherapy. I guess that's just how it goes, right?
In the meantime, I got a massive amount of crap from her, and now I’m stuck without a psychiatrist.🙂.
So, I’ve been on these pills way longer than I was originally supposed to be. But honestly? I feel great. And if I’m being real, the idea of stopping the meds and having to face those same old panic attacks all over again... yeah, that sounds like a nightmare I'm not ready to revisit.🙂.

Quick question—does staying on antidepressants longer than originally prescribed actually do any harm?
Sometimes I totally blank on taking my pill until late in the afternoon, and honestly? I don't even notice a difference... I guess it doesn't really move the needle for me one way or the other.

I honestly can’t tell the difference whether I’m sipping a Schwarzkopf here or over there—it all tastes exactly the same to me.

I feel like I’m doing too well, and honestly? It’s kind of terrifying. I know this probably sounds completely ridiculous, but am I overdoing it with the Prozac? Like, is it actually possible to have too much serotonin? I guess I’m just spiraling a little bit because things feel... fine. Too fine.

Honestly, if you ask me, I could probably drink them forever. I swear, they make me feel like my old self again.

Thanks in advance for any help or answers you guys can throw my way!

If they're working for you, you should definitely keep taking them. If you just quit cold turkey, there's a very real chance the anxiety, panic attacks, and intrusive thoughts will come roaring back.

That said, it probably wouldn't hurt to find a new psychiatrist—ideally someone who also does psychotherapy—so you can start that process and talk to them about your long-term plan for staying on the meds.

mystic2006 said:Starting today, I’m on a regimen of 1mg xanax SR three times a day, 80mg Zeldox at 1, 0, 1, and 37.5mg Effexor at 1, 0, 1. I'll check back in soon to let you all know how the side effects go!😵 😵 😵 😵

I can't help but wonder if that isn't a bit much medication for one person? Taking 1mg of xanax SR three times daily seems quite intense, if you ask me.
I take a similar setup myself, though I really only use the xanax as needed, since xanax is already pretty potent on its own—not to mention that 80mg dose of Zeldox. I have to ask, are you even able to walk straight?

The reason I'm asking is that I'm currently on 40mg of Zeldox, and honestly, it knocks me out so completely that I can barely stay on my feet.

I haven't seen any mention of "rejoflajt" in our recent discussions—unless, of course, I’ve missed some obscure technical jargon or perhaps a typo from one of those late-night forum ramblings—but if you're referring to a specific medication or a niche regulatory term, please do clarify. I tend to lose the thread when things aren't explicitly laid out, and frankly, my patience for deciphering cryptic shorthand is at an all-time low these days. If this is related to the ongoing discussions regarding FDA advisories or those endless clinical trial debates, let me know. Otherwise, I'm just staring at a word that looks more like a keyboard smash than actual information. kaže:
USA
Back in '96, Abbott Labs first applied for U. S. food and drug Administration approval for sertindole—though, looking back at how things were handled then, I can’t say I’m surprised by the timeline—but... The whole thing was pulled back in '98—an absolute disaster of a situation—once everyone realized the terrifyingly high risk of sudden death caused by QTc prolongation. I mean, just look at the numbers, if you can stomach them. We’re talking about a trial involving 2,000 patients where 27 people died unexpectedly... and 13 of those were sudden deaths. It’s enough to make anyone lose faith in the entire process—it really is. Just a grim reminder of why these things happen when oversight fails.

Europa in Europe
Back in the mid-nineties—specifically around 1996—Sertindole had already cleared the hurdles for approval and hit the market across nineteen different nations in Europa in Europe. But, well... things didn't exactly stay smooth sailing for long.Back in '98, the FDA pulled the plug on its marketing authorization—basically, they yanked the drug off the shelves entirely. It was a mess. But then, fast forward to 2002, and things started shifting again because of some fresh data coming down the pipeline. The FDA's advisory committee suggested that Sertindole could be reintroduced for restricted Use in clinical trials , with strong safeguards including extensive contraindications and warnings for patients AT risk of cardiac dysrhythmias. They weren't taking any chances, though—they recommended dropping the max dose from 24 mg down to 20 mg in almost every single case, and they insisted on rigorous ECG monitoring both before and during treatment. It’s all about those precautions, I suppose—one wrong move with heart rhythms and you're looking at a disaster.The marketing ban was finally lifted back in 2005—an era of significant shifts, if you can believe it.

I was digging through some old medical archives—it’s a bit of a rabbit hole, honestly—and stumbled upon the history of Sertindole again. It’s one of those cases that just leaves a bitter taste in your mouth if you think about it too long. You know, the kind of bureaucratic dance that makes you wonder if anyone is actually looking out for the little guy? So, here’s the deal: back in the day, this drug was supposed to be a big player for treating schizophrenia. But then the wheels fell off because of the heart risks—specifically those nasty cardiac dysrhythmias. I remember reading about a patient of my cousin's who had a similar scare with a different medication years ago; the anxiety of waiting for test results is enough to age a person a decade. Anyway, back to the point. The regulatory side of things is where it gets truly exhausting. After the initial fallout, there was all this back-and-forth with the authorities. Eventually, the FDA's advisory committee suggested that Sertindole could be reintroduced for restricted Use in clinical trials, with strong safeguards including extensive contraindications and warnings for patients AT risk of cardiac dysrhythmias. It’s a cautious, almost hesitant approach—typical of how these massive institutions operate once they've been burned. They don't exactly rush back into the fray. They move with this slow, deliberate skepticism that feels both necessary and incredibly frustrating when you consider how much time passes between these "re-evaluations." It’s just more proof that in the world of pharmacology, nothing is ever as simple as a single pill. 😲

http://www.facebook.com/topic.php?ui...88&topic=14057 😲

It seems the manufacturer behind that particular antipsychotic—Sertindole, or Serdolect, if you prefer the brand name—has decided to pull the plug. They’ve gone ahead and voluntarily suspended its availability entirely. It’s just one more thing in this increasingly unpredictable landscape of pharmaceutical stability—though I suppose I shouldn't be surprised, given how often these things seem to vanish from the shelves just when you think you have a handle on them. The whole thing boils down to those nagging, deeply unsettling reports regarding cardiac arrhythmias—and let’s not even get started on the instances of sudden cardiac death linked to its use. It's enough to make anyone lose sleep, really.
(Reference: (GBRCW) Communication, December 2, 1998)

Safety—or rather, the illusion of it—and those dreaded serious adverse events. It’s a heavy topic, isn't it? One minute you think you're navigating a clear path, and the next, you're staring down the barrel of a medical complication that feels like it came out of nowhere. I was reading some old reports the other day—reminded me of a time back in Chicago when a friend of mine thought he was just dealing with a bit of indigestion, only to find out he was facing something far more systemic—and it really strikes a chord regarding how we perceive risk. We want to believe the data is airtight, that the protocols are foolproof, but there's always that shadow of uncertainty hanging over every clinical trial and every new rollout. It’s exhausting, frankly. You look at the numbers, you look at the reported side effects, and you realize that "safety" is often a moving target, constantly being redefined by new findings and shifting regulations. It makes you wonder how much we actually know versus how much we simply hope is true.
Out of the 97 serious adverse events documented—and believe me, that is a staggering number—ten of them ended in fatalities. It’s quite grim when you sit down and actually parse through the data... ten lives gone. We’re looking at two suicides, three sudden deaths—specifically two heart attacks and one pulmonary embolism—and then there's this cluster of four "other" deaths that includes yet another pulmonary embolism, an unspecified case of intoxication, a myocardial infarction, and even a mesenteric artery infarction. To top it all off, there was one death where the cause remains completely unverified. It’s a messy, heartbreaking tally, really.

Thanks for the heads-up, Ray—really appreciate you sharing that info.

Larry Lewis said:

I haven't seen any mention of "rejoflajt" in our recent discussions—unless, of course, I’ve missed some obscure technical jargon or perhaps a typo from one of those late-night forum ramblings—but if you're referring to a specific medication or a niche regulatory term, please do clarify. I tend to lose the thread when things aren't explicitly laid out, and frankly, my patience for deciphering cryptic shorthand is at an all-time low these days. If this is related to the ongoing discussions regarding FDA advisories or those endless clinical trial debates, let me know. Otherwise, I'm just staring at a word that looks more like a keyboard smash than actual information. kaže:
USA
Back in '96, Abbott Labs first applied for U. S. food and drug Administration approval for sertindole—though, looking back at how things were handled then, I can’t say I’m surprised by the timeline—but... The whole thing was pulled back in '98—an absolute disaster of a situation—once everyone realized the terrifyingly high risk of sudden death caused by QTc prolongation. I mean, just look at the numbers, if you can stomach them. We’re talking about a trial involving 2,000 patients where 27 people died unexpectedly... and 13 of those were sudden deaths. It’s enough to make anyone lose faith in the entire process—it really is. Just a grim reminder of why these things happen when oversight fails.

Europa in Europe
Back in the mid-nineties—specifically around 1996—Sertindole had already cleared the hurdles for approval and hit the market across nineteen different nations in Europa in Europe. But, well... things didn't exactly stay smooth sailing for long.Back in '98, the FDA pulled the plug on its marketing authorization—basically, they yanked the drug off the shelves entirely. It was a mess. But then, fast forward to 2002, and things started shifting again because of some fresh data coming down the pipeline. The FDA's advisory committee suggested that Sertindole could be reintroduced for restricted Use in clinical trials , with strong safeguards including extensive contraindications and warnings for patients AT risk of cardiac dysrhythmias. They weren't taking any chances, though—they recommended dropping the max dose from 24 mg down to 20 mg in almost every single case, and they insisted on rigorous ECG monitoring both before and during treatment. It’s all about those precautions, I suppose—one wrong move with heart rhythms and you're looking at a disaster.The marketing ban was finally lifted back in 2005—an era of significant shifts, if you can believe it.

I was digging through some old medical archives—it’s a bit of a rabbit hole, honestly—and stumbled upon the history of Sertindole again. It’s one of those cases that just leaves a bitter taste in your mouth if you think about it too long. You know, the kind of bureaucratic dance that makes you wonder if anyone is actually looking out for the little guy? So, here’s the deal: back in the day, this drug was supposed to be a big player for treating schizophrenia. But then the wheels fell off because of the heart risks—specifically those nasty cardiac dysrhythmias. I remember reading about a patient of my cousin's who had a similar scare with a different medication years ago; the anxiety of waiting for test results is enough to age a person a decade. Anyway, back to the point. The regulatory side of things is where it gets truly exhausting. After the initial fallout, there was all this back-and-forth with the authorities. Eventually, the FDA's advisory committee suggested that Sertindole could be reintroduced for restricted Use in clinical trials, with strong safeguards including extensive contraindications and warnings for patients AT risk of cardiac dysrhythmias. It’s a cautious, almost hesitant approach—typical of how these massive institutions operate once they've been burned. They don't exactly rush back into the fray. They move with this slow, deliberate skepticism that feels both necessary and incredibly frustrating when you consider how much time passes between these "re-evaluations." It’s just more proof that in the world of pharmacology, nothing is ever as simple as a single pill. 😲

http://www.facebook.com/topic.php?ui...88&topic=14057 😲

It seems the manufacturer behind that particular antipsychotic—Sertindole, or Serdolect, if you prefer the brand name—has decided to pull the plug. They’ve gone ahead and voluntarily suspended its availability entirely. It’s just one more thing in this increasingly unpredictable landscape of pharmaceutical stability—though I suppose I shouldn't be surprised, given how often these things seem to vanish from the shelves just when you think you have a handle on them. The whole thing boils down to those nagging, deeply unsettling reports regarding cardiac arrhythmias—and let’s not even get started on the instances of sudden cardiac death linked to its use. It's enough to make anyone lose sleep, really.
(Reference: (GBRCW) Communication, December 2, 1998)

Safety—or rather, the illusion of it—and those dreaded serious adverse events. It’s a heavy topic, isn't it? One minute you think you're navigating a clear path, and the next, you're staring down the barrel of a medical complication that feels like it came out of nowhere. I was reading some old reports the other day—reminded me of a time back in Chicago when a friend of mine thought he was just dealing with a bit of indigestion, only to find out he was facing something far more systemic—and it really strikes a chord regarding how we perceive risk. We want to believe the data is airtight, that the protocols are foolproof, but there's always that shadow of uncertainty hanging over every clinical trial and every new rollout. It’s exhausting, frankly. You look at the numbers, you look at the reported side effects, and you realize that "safety" is often a moving target, constantly being redefined by new findings and shifting regulations. It makes you wonder how much we actually know versus how much we simply hope is true.
Out of the 97 serious adverse events documented—and believe me, that is a staggering number—ten of them ended in fatalities. It’s quite grim when you sit down and actually parse through the data... ten lives gone. We’re looking at two suicides, three sudden deaths—specifically two heart attacks and one pulmonary embolism—and then there's this cluster of four "other" deaths that includes yet another pulmonary embolism, an unspecified case of intoxication, a myocardial infarction, and even a mesenteric artery infarction. To top it all off, there was one death where the cause remains completely unverified. It’s a messy, heartbreaking tally, really.

Thanks for the heads-up, Ray—really appreciate you sharing that info.

Just look after that kind heart of yours instead!http://dl9.glitter-graphics.net/pub/...hoqm1jf0z1.gif

mystic2006 said:I have one more question regarding Xanax... Once a panic attack actually hits, is it better to take standard Xanax or stick with the Xanax SR for that slow release?

Just this briefly...what's your actual diagnosis, anyway?

If you’re dealing with an actual panic attack, I’ve always felt it’s better to stick with the standard xanax because it hits you almost instantly and settles things down right away. On the other hand, this SD version tends to kick in much more gradually; it takes about two hours to really peak, though it does stay in your system significantly longer—probably closer to ten hours or so.

My doctor originally prescribed the 2mg SD dose, but whenever I check at the local CVS, they tell me it’s out of stock. Apparently, they stopped manufacturing the 2mg strength entirely and only carry the 1mg SD now. To be honest, I still take the 2mg when I can find it, since even a single tablet usually feels like more than enough for me.

Greetings to all you good people. I’m curious to get your thoughts on a regimen consisting of half a 20 mg Seroxat pill combined with two 0.5 mg Xanax tablets. My diagnosis is hypersensitivity and anxiety, specifically regarding self-concern. It manifests through these overwhelming bouts of sadness that just leave me weeping. The trigger seems to be the summer heat; once the temperatures spike, my muscles tense up, and within about two weeks, I inevitably spiral into a deep depression.

ruggedmaker7 said:Greetings to all you good people. I’m curious to get your thoughts on a regimen consisting of half a 20 mg Seroxat pill combined with two 0.5 mg Xanax tablets. My diagnosis is hypersensitivity and anxiety, specifically regarding self-concern. It manifests through these overwhelming bouts of sadness that just leave me weeping. The trigger seems to be the summer heat; once the temperatures spike, my muscles tense up, and within about two weeks, I inevitably spiral into a deep depression.

Honestly, it sounds like a solid plan, but if I were you, I'd probably save the Helex for when you actually need it. Taking it long-term can definitely lead to dependency issues.

Matthew Castillo5 said:Honestly, it sounds like a solid plan, but if I were you, I'd probably save the Helex for when you actually need it. Taking it long-term can definitely lead to dependency issues.

Thanks a ton. I haven't actually started the AD yet, so my plan is to take them together at the start while keeping the Helex to a minimum. Hopefully, once the AD kicks in, I won't need the Helex anymore.

A few weeks back, I was watching this documentary series on DOQ when they featured some big-name celebrities opening up about their struggles with depression, anxiety, and bipolar disorder—specifically their experiences with AD. They brought in university professors and psychiatrists to weigh in, too. The doctors made a really interesting point: staying in a dark, depressive state without treatment actually causes your neurotransmitters to die off, creating this hollowed-out void in your brain—sort of like a network full of holes. On the flip side, for those who were consistently on AD, the neurotransmitters stayed active and didn't degrade.
I wanted to share this for anyone out there worried that taking AD long-term is somehow harmful.
The bottom line? It’s proven to be more than just safe; it's actually beneficial.
Later